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1523 related items for PubMed ID: 26134559

  • 1. Bax/Bak-dependent, Drp1-independent Targeting of X-linked Inhibitor of Apoptosis Protein (XIAP) into Inner Mitochondrial Compartments Counteracts Smac/DIABLO-dependent Effector Caspase Activation.
    Hamacher-Brady A, Brady NR.
    J Biol Chem; 2015 Sep 04; 290(36):22005-18. PubMed ID: 26134559
    [Abstract] [Full Text] [Related]

  • 2. Intramitochondrial recruitment of endolysosomes mediates Smac degradation and constitutes a novel intrinsic apoptosis antagonizing function of XIAP E3 ligase.
    Hamacher-Brady A, Choe SC, Krijnse-Locker J, Brady NR.
    Cell Death Differ; 2014 Dec 04; 21(12):1862-76. PubMed ID: 25080938
    [Abstract] [Full Text] [Related]

  • 3. Role for X-linked Inhibitor of apoptosis protein upstream of mitochondrial permeabilization.
    Owens TW, Foster FM, Valentijn A, Gilmore AP, Streuli CH.
    J Biol Chem; 2010 Jan 08; 285(2):1081-8. PubMed ID: 19875445
    [Abstract] [Full Text] [Related]

  • 4. Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy.
    Xian H, Liou YC.
    Autophagy; 2019 Dec 08; 15(12):2107-2125. PubMed ID: 30894073
    [Abstract] [Full Text] [Related]

  • 5. Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis.
    Parone PA, James DI, Da Cruz S, Mattenberger Y, Donzé O, Barja F, Martinou JC.
    Mol Cell Biol; 2006 Oct 08; 26(20):7397-408. PubMed ID: 17015472
    [Abstract] [Full Text] [Related]

  • 6. Caspase-mediated Bak activation and cytochrome c release during intrinsic apoptotic cell death in Jurkat cells.
    Shawgo ME, Shelton SN, Robertson JD.
    J Biol Chem; 2008 Dec 19; 283(51):35532-8. PubMed ID: 18927073
    [Abstract] [Full Text] [Related]

  • 7. The IAP-antagonist ARTS initiates caspase activation upstream of cytochrome C and SMAC/Diablo.
    Edison N, Zuri D, Maniv I, Bornstein B, Lev T, Gottfried Y, Kemeny S, Garcia-Fernandez M, Kagan J, Larisch S.
    Cell Death Differ; 2012 Feb 19; 19(2):356-68. PubMed ID: 21869827
    [Abstract] [Full Text] [Related]

  • 8. Drp1 is dispensable for apoptotic cytochrome c release in primed MCF10A and fibroblast cells but affects Bcl-2 antagonist-induced respiratory changes.
    Clerc P, Ge SX, Hwang H, Waddell J, Roelofs BA, Karbowski M, Sesaki H, Polster BM.
    Br J Pharmacol; 2014 Apr 19; 171(8):1988-99. PubMed ID: 24206264
    [Abstract] [Full Text] [Related]

  • 9. Tip30-induced apoptosis requires translocation of Bax and involves mitochondrial release of cytochrome c and Smac/DIABLO in hepatocellular carcinoma cells.
    Shi M, Yan SG, Xie ST, Wang HN.
    Biochim Biophys Acta; 2008 Feb 19; 1783(2):263-74. PubMed ID: 17997990
    [Abstract] [Full Text] [Related]

  • 10. Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro.
    MacFarlane M, Merrison W, Bratton SB, Cohen GM.
    J Biol Chem; 2002 Sep 27; 277(39):36611-6. PubMed ID: 12121969
    [Abstract] [Full Text] [Related]

  • 11. Bax/Bak promote sumoylation of DRP1 and its stable association with mitochondria during apoptotic cell death.
    Wasiak S, Zunino R, McBride HM.
    J Cell Biol; 2007 May 07; 177(3):439-50. PubMed ID: 17470634
    [Abstract] [Full Text] [Related]

  • 12. Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
    Kandasamy K, Srinivasula SM, Alnemri ES, Thompson CB, Korsmeyer SJ, Bryant JL, Srivastava RK.
    Cancer Res; 2003 Apr 01; 63(7):1712-21. PubMed ID: 12670926
    [Abstract] [Full Text] [Related]

  • 13. Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization.
    Arnoult D, Gaume B, Karbowski M, Sharpe JC, Cecconi F, Youle RJ.
    EMBO J; 2003 Sep 01; 22(17):4385-99. PubMed ID: 12941691
    [Abstract] [Full Text] [Related]

  • 14. Reovirus infection or ectopic expression of outer capsid protein micro1 induces apoptosis independently of the cellular proapoptotic proteins Bax and Bak.
    Wisniewski ML, Werner BG, Hom LG, Anguish LJ, Coffey CM, Parker JS.
    J Virol; 2011 Jan 01; 85(1):296-304. PubMed ID: 20980509
    [Abstract] [Full Text] [Related]

  • 15. X-linked inhibitor of apoptosis (XIAP) blocks Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of prostate cancer cells in the presence of mitochondrial activation: sensitization by overexpression of second mitochondria-derived activator of caspase/direct IAP-binding protein with low pl (Smac/DIABLO).
    Ng CP, Bonavida B.
    Mol Cancer Ther; 2002 Oct 01; 1(12):1051-8. PubMed ID: 12481428
    [Abstract] [Full Text] [Related]

  • 16. Activation of mitochondrial protease OMA1 by Bax and Bak promotes cytochrome c release during apoptosis.
    Jiang X, Jiang H, Shen Z, Wang X.
    Proc Natl Acad Sci U S A; 2014 Oct 14; 111(41):14782-7. PubMed ID: 25275009
    [Abstract] [Full Text] [Related]

  • 17. Dimerization of Smac is crucial for its mitochondrial retention by XIAP subsequent to mitochondrial outer membrane permeabilization.
    Flanagan L, Sebastia J, Delgado ME, Lennon JC, Rehm M.
    Biochim Biophys Acta; 2011 May 14; 1813(5):819-26. PubMed ID: 21354220
    [Abstract] [Full Text] [Related]

  • 18. Bax is essential for Drp1-mediated mitochondrial fission but not for mitochondrial outer membrane permeabilization caused by photodynamic therapy.
    Wu S, Zhou F, Zhang Z, Xing D.
    J Cell Physiol; 2011 Feb 14; 226(2):530-41. PubMed ID: 20683914
    [Abstract] [Full Text] [Related]

  • 19. BAK/BAX activation and cytochrome c release assays using isolated mitochondria.
    Renault TT, Floros KV, Chipuk JE.
    Methods; 2013 Jun 01; 61(2):146-55. PubMed ID: 23567751
    [Abstract] [Full Text] [Related]

  • 20. XIAP impairs Smac release from the mitochondria during apoptosis.
    Flanagan L, Sebastià J, Tuffy LP, Spring A, Lichawska A, Devocelle M, Prehn JH, Rehm M.
    Cell Death Dis; 2010 Jun 03; 1(6):e49. PubMed ID: 21364655
    [Abstract] [Full Text] [Related]

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