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Journal Abstract Search


380 related items for PubMed ID: 26142830

  • 1. Effect of rovatirelin, a novel thyrotropin-releasing hormone analog, on the central noradrenergic system.
    Ijiro T, Nakamura K, Ogata M, Inada H, Kiguchi S, Maruyama K, Nabekura J, Kobayashi M, Ishibashi H.
    Eur J Pharmacol; 2015 Aug 15; 761():413-22. PubMed ID: 26142830
    [Abstract] [Full Text] [Related]

  • 2. Excitation of locus coeruleus noradrenergic neurons by thyrotropin-releasing hormone.
    Ishibashi H, Nakahata Y, Eto K, Nabekura J.
    J Physiol; 2009 Dec 01; 587(Pt 23):5709-22. PubMed ID: 19840999
    [Abstract] [Full Text] [Related]

  • 3. Rovatirelin ameliorates motor dysfunction in the cytosine arabinoside-induced rat model of spinocerebellar degeneration via acetylcholine and dopamine neurotransmission.
    Ijiro T, Yaguchi A, Yokoyama A, Kiguchi S.
    Clin Exp Pharmacol Physiol; 2022 Sep 01; 49(9):950-958. PubMed ID: 35637550
    [Abstract] [Full Text] [Related]

  • 4. Ameliorating effect of rovatirelin on the ataxia in rolling mouse Nagoya.
    Ijiro T, Yaguchi A, Yokoyama A, Abe Y, Kiguchi S.
    Eur J Pharmacol; 2020 Sep 05; 882():173271. PubMed ID: 32534077
    [Abstract] [Full Text] [Related]

  • 5. Non-clinical pharmacokinetic profiles of rovatirelin, an orally available thyrotropin-releasing hormone analogue.
    Kobayashi K, Abe Y, Harada H, Oota E, Endo T, Takeda H.
    Xenobiotica; 2019 Jan 05; 49(1):106-119. PubMed ID: 29300135
    [Abstract] [Full Text] [Related]

  • 6. Lack of behavioral tolerance by repeated treatment with taltirelin hydrate, a thyrotropin-releasing hormone analog, in rats.
    Asai H, Asahi T, Yamamura M, Yamauchi-Kohno R, Saito A.
    Pharmacol Biochem Behav; 2005 Dec 05; 82(4):646-51. PubMed ID: 16368129
    [Abstract] [Full Text] [Related]

  • 7. Discovery of the Orally Effective Thyrotropin-Releasing Hormone Mimetic: 1-{N-[(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-3-(thiazol-4-yl)-l-alanyl}-(2R)-2-methylpyrrolidine Trihydrate (Rovatirelin Hydrate).
    Kobayashi N, Sato N, Fujimura Y, Kihara T, Sugita K, Takahashi K, Koike K, Sugawara T, Tada Y, Nakai H, Yoshikawa T.
    ACS Omega; 2018 Oct 31; 3(10):13647-13666. PubMed ID: 30411045
    [Abstract] [Full Text] [Related]

  • 8. Chronic citalopram administration desensitizes prefrontal cortex but not somatodendritic α2-adrenoceptors in rat brain.
    Fernández-Pastor B, Ortega JE, Grandoso L, Castro E, Ugedo L, Pazos Á, Meana JJ.
    Neuropharmacology; 2017 Mar 01; 114():114-122. PubMed ID: 27908769
    [Abstract] [Full Text] [Related]

  • 9. [Synthesis and pharmacological action of TRH analog peptide (Taltirelin)].
    Yamamura M, Suzuki M, Matsumoto K.
    Nihon Yakurigaku Zasshi; 1997 Oct 01; 110 Suppl 1():33P-38P. PubMed ID: 9503402
    [Abstract] [Full Text] [Related]

  • 10. Diversity of thyrotropin-releasing hormone receptors in the pituitary and discrete brain regions of rats.
    Asai H, Kinoshita K, Yamamura M, Matsuoka Y.
    Jpn J Pharmacol; 1999 Mar 01; 79(3):313-7. PubMed ID: 10230859
    [Abstract] [Full Text] [Related]

  • 11. Pharmacokinetic Drug Interactions of an Orally Available TRH Analog (Rovatirelin) With a CYP3A4/5 and P-Glycoprotein Inhibitor (Itraconazole).
    Kobayashi K, Abe Y, Kawai A, Furihata T, Endo T, Takeda H.
    J Clin Pharmacol; 2020 Oct 01; 60(10):1314-1323. PubMed ID: 32459872
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and evaluation of in vivo anti-hypothermic effect of all stereoisomers of the thyrotropin-releasing hormone mimetic: Rovatirelin Hydrate.
    Kobayashi N, Sato N, Sugita K, Takahashi K, Sugawara T, Tada Y, Yoshikawa T.
    J Pept Sci; 2019 Dec 01; 25(12):e3228. PubMed ID: 31713944
    [Abstract] [Full Text] [Related]

  • 13. Chronic fluoxetine reverses the effects of chronic corticosterone treatment on α2-adrenoceptors in the rat frontal cortex but not locus coeruleus.
    Horrillo I, Ortega JE, Diez-Alarcia R, Urigüen L, Meana JJ.
    Neuropharmacology; 2019 Nov 01; 158():107731. PubMed ID: 31376424
    [Abstract] [Full Text] [Related]

  • 14. Effects of taltirelin hydrate (TA-0910), a novel thyrotropin-releasing hormone analog, on in vivo dopamine release and turnover in rat brain.
    Fukuchi I, Asahi T, Kawashima K, Kawashima Y, Yamamura M, Matsuoka Y, Kinoshita K.
    Arzneimittelforschung; 1998 Apr 01; 48(4):353-9. PubMed ID: 9608876
    [Abstract] [Full Text] [Related]

  • 15.
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  • 16. Noradrenergic lesion of the locus coeruleus increases the firing activity of the medial prefrontal cortex pyramidal neurons and the role of alpha2-adrenoceptors in normal and medial forebrain bundle lesioned rats.
    Wang Y, Zhang QJ, Liu J, Ali U, Gui ZH, Hui YP, Wang T, Chen L, Li Q.
    Brain Res; 2010 Apr 09; 1324():64-74. PubMed ID: 20153300
    [Abstract] [Full Text] [Related]

  • 17. Reversal of hemorrhagic shock in rats using the metabolically stable thyrotropin-releasing hormone analog taltirelin hydrate.
    Asai H, Watanabe Y, Yamauchi-Kohno R, Doi O.
    J Recept Signal Transduct Res; 2011 Dec 09; 31(6):416-22. PubMed ID: 22044177
    [Abstract] [Full Text] [Related]

  • 18.
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  • 19. Brain receptor binding characteristics and pharmacokinetic-pharmacodynamic analysis of thyrotropin-releasing hormone analogues.
    Urayama A, Yamada S, Hirano K, Deguchi Y, Kimura R.
    Life Sci; 2001 Dec 28; 70(6):647-57. PubMed ID: 11833715
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and Evaluation of in Vivo Anti-hypothermic Effect of the N- and C-Terminus Modified Thyrotropin-Releasing Hormone Mimetic: [(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-[3-(thiazol-4-yl)-L-alanyl]-L-prolinamide.
    Kobayashi N, Sato N, Sugita K, Kihara T, Koike K, Sugawara T, Tada Y, Yoshikawa T.
    Chem Pharm Bull (Tokyo); 2021 Dec 28; 69(4):314-324. PubMed ID: 33790077
    [Abstract] [Full Text] [Related]


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