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Journal Abstract Search

912 related items for PubMed ID: 26153346

  • 1. LYG-202 exerts antitumor effect on PI3K/Akt signaling pathway in human breast cancer cells.
    Zhao Y, Wang X, Sun Y, Zhou Y, Yin Y, Ding Y, Li Z, Guo Q, Lu N.
    Apoptosis; 2015 Sep; 20(9):1253-69. PubMed ID: 26153346
    [Abstract] [Full Text] [Related]

  • 2. LYG-202 inhibits the proliferation of human colorectal carcinoma HCT-116 cells through induction of G1/S cell cycle arrest and apoptosis via p53 and p21(WAF1/Cip1) expression.
    Liu W, Dai Q, Lu N, Wei L, Ha J, Rong J, Mu R, You Q, Li Z, Guo Q.
    Biochem Cell Biol; 2011 Jun; 89(3):287-98. PubMed ID: 21491996
    [Abstract] [Full Text] [Related]

  • 3. LYG-202, a new flavonoid with a piperazine substitution, shows antitumor effects in vivo and in vitro.
    Zeng S, Liu W, Nie FF, Zhao Q, Rong JJ, Wang J, Tao L, Qi Q, Lu N, Li ZY, Guo QL.
    Biochem Biophys Res Commun; 2009 Aug 07; 385(4):551-6. PubMed ID: 19481059
    [Abstract] [Full Text] [Related]

  • 4. Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells.
    Kuo PL, Chen CY, Hsu YL.
    Cancer Res; 2007 Aug 01; 67(15):7406-20. PubMed ID: 17671211
    [Abstract] [Full Text] [Related]

  • 5. A Novel Bromophenol Derivative BOS-102 Induces Cell Cycle Arrest and Apoptosis in Human A549 Lung Cancer Cells via ROS-Mediated PI3K/Akt and the MAPK Signaling Pathway.
    Guo CL, Wang LJ, Zhao Y, Liu H, Li XQ, Jiang B, Luo J, Guo SJ, Wu N, Shi DY.
    Mar Drugs; 2018 Jan 25; 16(2):. PubMed ID: 29370087
    [Abstract] [Full Text] [Related]

  • 6. Bufalin induces G0/G1 phase arrest through inhibiting the levels of cyclin D, cyclin E, CDK2 and CDK4, and triggers apoptosis via mitochondrial signaling pathway in T24 human bladder cancer cells.
    Huang WW, Yang JS, Pai SJ, Wu PP, Chang SJ, Chueh FS, Fan MJ, Chiou SM, Kuo HM, Yeh CC, Chen PY, Tsuzuki M, Chung JG.
    Mutat Res; 2012 Apr 01; 732(1-2):26-33. PubMed ID: 22285700
    [Abstract] [Full Text] [Related]

  • 7. Furazolidone induces apoptosis through activating reactive oxygen species-dependent mitochondrial signaling pathway and suppressing PI3K/Akt signaling pathway in HepG2 cells.
    Deng S, Tang S, Zhang S, Zhang C, Wang C, Zhou Y, Dai C, Xiao X.
    Food Chem Toxicol; 2015 Jan 01; 75():173-86. PubMed ID: 25434308
    [Abstract] [Full Text] [Related]

  • 8. Reactive oxygen species-mitochondria pathway involved in LYG-202-induced apoptosis in human hepatocellular carcinoma HepG(2) cells.
    Chen FH, Zhang LB, Qiang L, Yang Z, Wu T, Zou MJ, Tao L, You QD, Li ZY, Yang Y, Guo QL.
    Cancer Lett; 2010 Oct 01; 296(1):96-105. PubMed ID: 20580989
    [Abstract] [Full Text] [Related]

  • 9. LYG-202 augments tumor necrosis factor-α-induced apoptosis via attenuating casein kinase 2-dependent nuclear factor-κB pathway in HepG2 cells.
    Chen FH, Lu N, Zhang HW, Zhao L, He LC, Sun HP, You QD, Li ZY, Guo QL.
    Mol Pharmacol; 2012 Nov 01; 82(5):958-71. PubMed ID: 22909797
    [Abstract] [Full Text] [Related]

  • 10. Human urine extract CDA-2 induces apoptosis of myelodysplastic syndrome-derived MUTZ-1 cells through the PI3K/Akt signaling pathway in a caspase-3-dependent manner.
    Huang J, Yang M, Liu H, Jin J.
    Acta Pharmacol Sin; 2008 Aug 01; 29(8):951-64. PubMed ID: 18664328
    [Abstract] [Full Text] [Related]

  • 11. Combination treatment of ligustrazine piperazine derivate DLJ14 and adriamycin inhibits progression of resistant breast cancer through inhibition of the EGFR/PI3K/Akt survival pathway and induction of apoptosis.
    Chen J, Wang W, Wang H, Liu X, Guo X.
    Drug Discov Ther; 2014 Feb 01; 8(1):33-41. PubMed ID: 24647156
    [Abstract] [Full Text] [Related]

  • 12. LW-214, a newly synthesized flavonoid, induces intrinsic apoptosis pathway by down-regulating Trx-1 in MCF-7 human breast cells.
    Pan D, Li W, Miao H, Yao J, Li Z, Wei L, Zhao L, Guo Q.
    Biochem Pharmacol; 2014 Feb 15; 87(4):598-610. PubMed ID: 24374359
    [Abstract] [Full Text] [Related]

  • 13. Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway.
    Han B, Jiang P, Li Z, Yu Y, Huang T, Ye X, Li X.
    Phytomedicine; 2018 Sep 15; 48():152-160. PubMed ID: 30195873
    [Abstract] [Full Text] [Related]

  • 14. Molecular targeting of Akt by thymoquinone promotes G(1) arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells.
    Rajput S, Kumar BN, Dey KK, Pal I, Parekh A, Mandal M.
    Life Sci; 2013 Nov 13; 93(21):783-90. PubMed ID: 24044882
    [Abstract] [Full Text] [Related]

  • 15. Isoliquiritigenin induces growth inhibition and apoptosis through downregulating arachidonic acid metabolic network and the deactivation of PI3K/Akt in human breast cancer.
    Li Y, Zhao H, Wang Y, Zheng H, Yu W, Chai H, Zhang J, Falck JR, Guo AM, Yue J, Peng R, Yang J.
    Toxicol Appl Pharmacol; 2013 Oct 01; 272(1):37-48. PubMed ID: 23747687
    [Abstract] [Full Text] [Related]

  • 16. Ginsenoside Rk1 induces cell cycle arrest and apoptosis in MDA-MB-231 triple negative breast cancer cells.
    Hong Y, Fan D.
    Toxicology; 2019 Apr 15; 418():22-31. PubMed ID: 30797898
    [Abstract] [Full Text] [Related]

  • 17. Esculetin exerts antitumor effect on human gastric cancer cells through IGF-1/PI3K/Akt signaling pathway.
    Wang G, Lu M, Yao Y, Wang J, Li J.
    Eur J Pharmacol; 2017 Nov 05; 814():207-215. PubMed ID: 28847482
    [Abstract] [Full Text] [Related]

  • 18. Involvement of Akt/NF-κB pathway in N6-isopentenyladenosine-induced apoptosis in human breast cancer cells.
    Laezza C, Malfitano AM, Di Matola T, Ricchi P, Bifulco M.
    Mol Carcinog; 2010 Oct 05; 49(10):892-901. PubMed ID: 20672320
    [Abstract] [Full Text] [Related]

  • 19. Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
    Pan ST, Qin Y, Zhou ZW, He ZX, Zhang X, Yang T, Yang YX, Wang D, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Oct 05; 9():1601-26. PubMed ID: 25834400
    [Abstract] [Full Text] [Related]

  • 20. A novel derivative of quinazoline, WYK431 induces G2/M phase arrest and apoptosis in human gastric cancer BGC823 cells through the PI3K/Akt pathway.
    Wang TE, Wang YK, Jin J, Xu BL, Chen XG.
    Int J Oncol; 2014 Aug 05; 45(2):771-81. PubMed ID: 24859921
    [Abstract] [Full Text] [Related]

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