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342 related items for PubMed ID: 26168894
1. Phosphodiesterase-4 inhibitors ameliorates cognitive deficits in deoxycorticosterone acetate induced hypertensive rats via cAMP/CREB signaling system. Jabaris SS, Sumathy H, Girish R, Narayanan S, Sugumar M, Saravana Babu C, Thanikachalam S, Thanikachalam M. Brain Res; 2015 Oct 05; 1622():279-91. PubMed ID: 26168894 [Abstract] [Full Text] [Related]
2. Effects of rolipram and roflumilast, phosphodiesterase-4 inhibitors, on hypertension-induced defects in memory function in rats. Jabaris SG, Sumathy H, Kumar RS, Narayanan S, Thanikachalam S, Babu CS. Eur J Pharmacol; 2015 Jan 05; 746():138-47. PubMed ID: 25446433 [Abstract] [Full Text] [Related]
6. Phosphodiestrase-1 and 4 inhibitors ameliorate liver fibrosis in rats: Modulation of cAMP/CREB/TLR4 inflammatory and fibrogenic pathways. Essam RM, Ahmed LA, Abdelsalam RM, El-Khatib AS. Life Sci; 2019 Apr 01; 222():245-254. PubMed ID: 30858122 [Abstract] [Full Text] [Related]
7. Inhibition of phosphodiesterase-4 reverses memory deficits produced by Aβ25-35 or Aβ1-40 peptide in rats. Cheng YF, Wang C, Lin HB, Li YF, Huang Y, Xu JP, Zhang HT. Psychopharmacology (Berl); 2010 Oct 01; 212(2):181-91. PubMed ID: 20640406 [Abstract] [Full Text] [Related]
8. FFPM, a PDE4 inhibitor, reverses learning and memory deficits in APP/PS1 transgenic mice via cAMP/PKA/CREB signaling and anti-inflammatory effects. Guo H, Cheng Y, Wang C, Wu J, Zou Z, Niu B, Yu H, Wang H, Xu J. Neuropharmacology; 2017 Apr 01; 116():260-269. PubMed ID: 28065587 [Abstract] [Full Text] [Related]
10. Roflumilast and tadalafil improve learning and memory deficits in intracerebroventricular Aβ1-42 rat model of Alzheimer's disease through modulations of hippocampal cAMP/cGMP/BDNF signaling pathway. Hasan N, Zameer S, Najmi AK, Parvez S, Yar MS, Akhtar M. Pharmacol Rep; 2021 Oct 01; 73(5):1287-1302. PubMed ID: 33860460 [Abstract] [Full Text] [Related]
11. cAMP/PKA-CREB-BDNF signaling pathway in hippocampus mediates cyclooxygenase 2-induced learning/memory deficits of rats subjected to chronic unpredictable mild stress. Luo Y, Kuang S, Li H, Ran D, Yang J. Oncotarget; 2017 May 30; 8(22):35558-35572. PubMed ID: 28415673 [Abstract] [Full Text] [Related]
12. The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses. Vanmierlo T, Creemers P, Akkerman S, van Duinen M, Sambeth A, De Vry J, Uz T, Blokland A, Prickaerts J. Behav Brain Res; 2016 Apr 15; 303():26-33. PubMed ID: 26794595 [Abstract] [Full Text] [Related]
13. Effects of a phosphodiesterase IV inhibitor rolipram on microsphere embolism-induced defects in memory function and cerebral cyclic AMP signal transduction system in rats. Nagakura A, Niimura M, Takeo S. Br J Pharmacol; 2002 Apr 15; 135(7):1783-93. PubMed ID: 11934820 [Abstract] [Full Text] [Related]
14. Phosphodiesterase-4 inhibition augments human lung fibroblast vascular endothelial growth factor production induced by prostaglandin E2. Ikari J, Michalski JM, Iwasawa S, Gunji Y, Nogel S, Park JH, Nelson AJ, Farid M, Wang X, Schulte N, Basma H, Toews ML, Feghali-Bostwick C, Tenor H, Liu X, Rennard SI. Am J Respir Cell Mol Biol; 2013 Oct 15; 49(4):571-81. PubMed ID: 23656623 [Abstract] [Full Text] [Related]
15. Phosphodiesterase inhibitors enhance object memory independent of cerebral blood flow and glucose utilization in rats. Rutten K, Van Donkelaar EL, Ferrington L, Blokland A, Bollen E, Steinbusch HW, Kelly PA, Prickaerts JH. Neuropsychopharmacology; 2009 Jul 15; 34(8):1914-25. PubMed ID: 19262466 [Abstract] [Full Text] [Related]
16. Object memory enhancement by combining sub-efficacious doses of specific phosphodiesterase inhibitors. Bollen E, Akkerman S, Puzzo D, Gulisano W, Palmeri A, D'Hooge R, Balschun D, Steinbusch HW, Blokland A, Prickaerts J. Neuropharmacology; 2015 Aug 15; 95():361-6. PubMed ID: 25896769 [Abstract] [Full Text] [Related]