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Journal Abstract Search

810 related items for PubMed ID: 26177395

  • 1. Design, Synthesis and Molecular Docking Studies of Novel Indole-Pyrimidine Hybrids as Tubulin Polymerization Inhibitors.
    Hu MJ, Zhang B, Yang HK, Liu Y, Chen YR, Ma TZ, Lu L, You WW, Zhao PL.
    Chem Biol Drug Des; 2015 Dec; 86(6):1491-500. PubMed ID: 26177395
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and biological evaluation of novel indole-pyrimidine hybrids bearing morpholine and thiomorpholine moieties.
    Diao PC, Li Q, Hu MJ, Ma YF, You WW, Hong KH, Zhao PL.
    Eur J Med Chem; 2017 Jul 07; 134():110-118. PubMed ID: 28410492
    [Abstract] [Full Text] [Related]

  • 3. Synthesis, biological evaluation, and molecular docking studies of novel 1-benzene acyl-2-(1-methylindol-3-yl)-benzimidazole derivatives as potential tubulin polymerization inhibitors.
    Wang YT, Qin YJ, Yang N, Zhang YL, Liu CH, Zhu HL.
    Eur J Med Chem; 2015 Jun 24; 99():125-37. PubMed ID: 26070164
    [Abstract] [Full Text] [Related]

  • 4. Synthesis and biological evaluation of 2,4,5-substituted pyrimidines as a new class of tubulin polymerization inhibitors.
    Xie F, Zhao H, Li D, Chen H, Quan H, Shi X, Lou L, Hu Y.
    J Med Chem; 2011 May 12; 54(9):3200-5. PubMed ID: 21480626
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  • 5. Synthesis and Preclinical Evaluation of Indole Triazole Conjugates as Microtubule Targeting Agents that are Effective against MCF-7 Breast Cancer Cell Lines.
    Yele V, Pindiprolu SKSS, Sana S, Ramamurty DSVNM, Madasi JRK, Vadlamani S.
    Anticancer Agents Med Chem; 2021 May 12; 21(8):1047-1055. PubMed ID: 32981511
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  • 6. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
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  • 7. Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors.
    Qin YJ, Li YJ, Jiang AQ, Yang MR, Zhu QZ, Dong H, Zhu HL.
    Eur J Med Chem; 2015 Apr 13; 94():447-57. PubMed ID: 25828827
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  • 8. Novel [1,2,4]triazolo[1,5-a]pyrimidine derivatives as potent antitubulin agents: Design, multicomponent synthesis and antiproliferative activities.
    Yang F, Yu LZ, Diao PC, Jian XE, Zhou MF, Jiang CS, You WW, Ma WF, Zhao PL.
    Bioorg Chem; 2019 Nov 13; 92():103260. PubMed ID: 31525523
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of curcumin inspired indole analogues as tubulin polymerization inhibitors.
    Sri Ramya PV, Angapelly S, Guntuku L, Singh Digwal C, Nagendra Babu B, Naidu VGM, Kamal A.
    Eur J Med Chem; 2017 Feb 15; 127():100-114. PubMed ID: 28038323
    [Abstract] [Full Text] [Related]

  • 10. Discovery and molecular modeling of novel 1-indolyl acetate--5-nitroimidazole targeting tubulin polymerization as antiproliferative agents.
    Duan YT, Sang YL, Makawana JA, Teraiya SB, Yao YF, Tang DJ, Tao XX, Zhu HL.
    Eur J Med Chem; 2014 Oct 06; 85():341-51. PubMed ID: 25105922
    [Abstract] [Full Text] [Related]

  • 11. Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors.
    Baytas SN, Inceler N, Yilmaz A, Olgac A, Menevse S, Banoglu E, Hamel E, Bortolozzi R, Viola G.
    Bioorg Med Chem; 2014 Jun 15; 22(12):3096-104. PubMed ID: 24816066
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and biological evaluation of indole-2-carbohydrazides and thiazolidinyl-indole-2-carboxamides as potent tubulin polymerization inhibitors.
    Kazan F, Yagci ZB, Bai R, Ozkirimli E, Hamel E, Ozkirimli S.
    Comput Biol Chem; 2019 Jun 15; 80():512-523. PubMed ID: 31185422
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  • 13. Hybrid Pharmacophore Design, Molecular Docking, Synthesis, and Biological Evaluation of Novel Aldimine-Type Schiff Base Derivatives as Tubulin Polymerization Inhibitor.
    Ameri A, Khodarahmi G, Forootanfar H, Hassanzadeh F, Hakimelahi GH.
    Chem Biodivers; 2018 Mar 15; 15(3):e1700518. PubMed ID: 29292595
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  • 14. Design, synthesis, and bioevaluation of pyrazolo[1,5-a]pyrimidine derivatives as tubulin polymerization inhibitors targeting the colchicine binding site with potent anticancer activities.
    Li G, Wang Y, Li L, Ren Y, Deng X, Liu J, Wang W, Luo M, Liu S, Chen J.
    Eur J Med Chem; 2020 Sep 15; 202():112519. PubMed ID: 32650183
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  • 15. 4,5-Diaryl-3H-1,2-dithiole-3-thiones and related compounds as combretastatin A-4/oltipraz hybrids: Synthesis, molecular modelling and evaluation as antiproliferative agents and inhibitors of tubulin.
    Wang Z, Qi H, Shen Q, Lu G, Li M, Bao K, Wu Y, Zhang W.
    Eur J Med Chem; 2016 Oct 21; 122():520-529. PubMed ID: 27428395
    [Abstract] [Full Text] [Related]

  • 16. Discovery of highly potent tubulin polymerization inhibitors: Design, synthesis, and structure-activity relationships of novel 2,7-diaryl-[1,2,4]triazolo[1,5-a]pyrimidines.
    Huo XS, Jian XE, Ou-Yang J, Chen L, Yang F, Lv DX, You WW, Rao JJ, Zhao PL.
    Eur J Med Chem; 2021 Aug 05; 220():113449. PubMed ID: 33895499
    [Abstract] [Full Text] [Related]

  • 17. Design, synthesis and biological evaluation of 2-alkoxycarbonyl-3-anilinoindoles as a new class of potent inhibitors of tubulin polymerization.
    Romagnoli R, Prencipe F, Oliva P, Kimatrai Salvador M, Brancale A, Ferla S, Hamel E, Viola G, Bortolozzi R, Persoons L, Balzarini J, Liekens S, Schols D.
    Bioorg Chem; 2020 Apr 05; 97():103665. PubMed ID: 32086053
    [Abstract] [Full Text] [Related]

  • 18. Anti-proliferative potential of triphenyl substituted pyrimidines against MDA-MB-231, HCT-116 and HT-29 cancer cell lines.
    Ranjan Dwivedi A, Kumar V, Kaur H, Kumar N, Prakash Yadav R, Poduri R, Baranwal S, Kumar V.
    Bioorg Med Chem Lett; 2020 Oct 15; 30(20):127468. PubMed ID: 32768647
    [Abstract] [Full Text] [Related]

  • 19. Design and synthesis of aminostilbene-arylpropenones as tubulin polymerization inhibitors.
    Kamal A, Kumar GB, Polepalli S, Shaik AB, Reddy VS, Reddy MK, Reddy ChR, Mahesh R, Kapure JS, Jain N.
    ChemMedChem; 2014 Nov 15; 9(11):2565-79. PubMed ID: 25146959
    [Abstract] [Full Text] [Related]

  • 20. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP, Wu CY, Hsieh HP, Chang CY, Chen CM, Kuo CC, Chang JY.
    J Med Chem; 2007 Sep 06; 50(18):4548-52. PubMed ID: 17685504
    [Abstract] [Full Text] [Related]

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