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Journal Abstract Search

256 related items for PubMed ID: 26188358

  • 1. Inhibition of Bcl-xL overcomes polyploidy resistance and leads to apoptotic cell death in acute myeloid leukemia cells.
    Zhou W, Xu J, Gelston E, Wu X, Zou Z, Wang B, Zeng Y, Wang H, Liu A, Xu L, Liu Q.
    Oncotarget; 2015 Aug 28; 6(25):21557-71. PubMed ID: 26188358
    [Abstract] [Full Text] [Related]

  • 2. CyclinG1 Amplification Enhances Aurora Kinase Inhibitor-Induced Polyploid Resistance and Inhibition of Bcl-2 Pathway Reverses the Resistance.
    Zhang W, Xu J, Ji D, Li Z, He W, Yang F, Lan H, Wang Y, Wu Z, Liu X, Huang S, Li L, Zhou W.
    Cell Physiol Biochem; 2017 Aug 28; 43(1):94-107. PubMed ID: 28848145
    [Abstract] [Full Text] [Related]

  • 3. Role of cyclin B1/Cdc2 in mediating Bcl-XL phosphorylation and apoptotic cell death following nocodazole-induced mitotic arrest.
    Choi HJ, Zhu BT.
    Mol Carcinog; 2014 Feb 28; 53(2):125-37. PubMed ID: 22949227
    [Abstract] [Full Text] [Related]

  • 4. Repression of Mcl-1 expression by the CDC7/CDK9 inhibitor PHA-767491 overcomes bone marrow stroma-mediated drug resistance in AML.
    O' Reilly E, Dhami SPS, Baev DV, Ortutay C, Halpin-McCormick A, Morrell R, Santocanale C, Samali A, Quinn J, O'Dwyer ME, Szegezdi E.
    Sci Rep; 2018 Oct 25; 8(1):15752. PubMed ID: 30361682
    [Abstract] [Full Text] [Related]

  • 5. The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.
    Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N.
    Hepatology; 2010 Oct 25; 52(4):1310-21. PubMed ID: 20799354
    [Abstract] [Full Text] [Related]

  • 6. Synergistic cooperation between ABT-263 and MEK1/2 inhibitor: effect on apoptosis and proliferation of acute myeloid leukemia cells.
    Airiau K, Prouzet-Mauléon V, Rousseau B, Pigneux A, Jeanneteau M, Giraudon M, Allou K, Dubus P, Belloc F, Mahon FX.
    Oncotarget; 2016 Jan 05; 7(1):845-59. PubMed ID: 26625317
    [Abstract] [Full Text] [Related]

  • 7. Targeting MCL-1/BCL-XL Forestalls the Acquisition of Resistance to ABT-199 in Acute Myeloid Leukemia.
    Lin KH, Winter PS, Xie A, Roth C, Martz CA, Stein EM, Anderson GR, Tingley JP, Wood KC.
    Sci Rep; 2016 Jun 10; 6():27696. PubMed ID: 27283158
    [Abstract] [Full Text] [Related]

  • 8. Upregulated cyclin B1/CDK1 mediates apoptosis following 2-methoxyestradiol-induced mitotic catastrophe: Role of Bcl-XL phosphorylation.
    Choi HJ, Zhu BT.
    Steroids; 2019 Oct 10; 150():108381. PubMed ID: 30797877
    [Abstract] [Full Text] [Related]

  • 9. The transcription factor Wilms tumor 1 confers resistance in myeloid leukemia cells against the proapoptotic therapeutic agent TRAIL (tumor necrosis factor α-related apoptosis-inducing ligand) by regulating the antiapoptotic protein Bcl-xL.
    Bansal H, Seifert T, Bachier C, Rao M, Tomlinson G, Iyer SP, Bansal S.
    J Biol Chem; 2012 Sep 21; 287(39):32875-80. PubMed ID: 22898820
    [Abstract] [Full Text] [Related]

  • 10. Effects of the aurora kinase inhibitors AZD1152-HQPA and ZM447439 on growth arrest and polyploidy in acute myeloid leukemia cell lines and primary blasts.
    Walsby E, Walsh V, Pepper C, Burnett A, Mills K.
    Haematologica; 2008 May 21; 93(5):662-9. PubMed ID: 18367484
    [Abstract] [Full Text] [Related]

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  • 12. c-Myc plays part in drug resistance mediated by bone marrow stromal cells in acute myeloid leukemia.
    Xia B, Tian C, Guo S, Zhang L, Zhao D, Qu F, Zhao W, Wang Y, Wu X, Da W, Wei S, Zhang Y.
    Leuk Res; 2015 Jan 21; 39(1):92-9. PubMed ID: 25443862
    [Abstract] [Full Text] [Related]

  • 13. The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines.
    Dick TE, Hengst JA, Fox TE, Colledge AL, Kale VP, Sung SS, Sharma A, Amin S, Loughran TP, Kester M, Wang HG, Yun JK.
    J Pharmacol Exp Ther; 2015 Mar 21; 352(3):494-508. PubMed ID: 25563902
    [Abstract] [Full Text] [Related]

  • 14. A novel therapeutic combination sequentially targeting aurora B and Bcl-xL in hepatocellular carcinoma.
    Matsunaga H, Tanaka S, Aihara A, Ogawa K, Matsumura S, Ban D, Ochiai T, Irie T, Kudo A, Nakamura N, Arii S, Tanabe M.
    Ann Surg Oncol; 2015 Sep 21; 22(9):3079-86. PubMed ID: 25524010
    [Abstract] [Full Text] [Related]

  • 15. BH3 mimetic ABT-737 neutralizes resistance to FLT3 inhibitor treatment mediated by FLT3-independent expression of BCL2 in primary AML blasts.
    Kohl TM, Hellinger C, Ahmed F, Buske C, Hiddemann W, Bohlander SK, Spiekermann K.
    Leukemia; 2007 Aug 21; 21(8):1763-72. PubMed ID: 17554384
    [Abstract] [Full Text] [Related]

  • 16. CXCR4 chemokine receptor signaling induces apoptosis in acute myeloid leukemia cells via regulation of the Bcl-2 family members Bcl-XL, Noxa, and Bak.
    Kremer KN, Peterson KL, Schneider PA, Meng XW, Dai H, Hess AD, Smith BD, Rodriguez-Ramirez C, Karp JE, Kaufmann SH, Hedin KE.
    J Biol Chem; 2013 Aug 09; 288(32):22899-914. PubMed ID: 23798675
    [Abstract] [Full Text] [Related]

  • 17. Mcl-1 down-regulation potentiates ABT-737 lethality by cooperatively inducing Bak activation and Bax translocation.
    Chen S, Dai Y, Harada H, Dent P, Grant S.
    Cancer Res; 2007 Jan 15; 67(2):782-91. PubMed ID: 17234790
    [Abstract] [Full Text] [Related]

  • 18. Pan-class I  PI3-kinase inhibitor BKM120 induces MEK1/2-dependent mitotic catastrophe in non-Hodgkin lymphoma leading to apoptosis or polyploidy determined by Bax/Bak and p53.
    Müller A, Gillissen B, Richter A, Richter A, Chumduri C, Daniel PT, Scholz CW.
    Cell Death Dis; 2018 Mar 07; 9(3):384. PubMed ID: 29515122
    [Abstract] [Full Text] [Related]

  • 19. Curcumin Combined with Thalidomide Reduces Expression of STAT3 and Bcl-xL, Leading to Apoptosis in Acute Myeloid Leukemia Cell Lines.
    Mohammadi Kian M, Salemi M, Bahadoran M, Haghi A, Dashti N, Mohammadi S, Rostami S, Chahardouli B, Babakhani D, Nikbakht M.
    Drug Des Devel Ther; 2020 Mar 07; 14():185-194. PubMed ID: 32021103
    [Abstract] [Full Text] [Related]

  • 20. Bcl-xl and Mcl-1 are the major determinants of the apoptotic response to dual PI3K and MEK blockage.
    Jokinen E, Koivunen JP.
    Int J Oncol; 2015 Sep 07; 47(3):1103-10. PubMed ID: 26135106
    [Abstract] [Full Text] [Related]

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