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169 related items for PubMed ID: 26188518

  • 1. SH2 domain-containing inositol 5-phosphatase (SHIP2) regulates de-novo lipogenesis and secretion of apoB100 containing lipoproteins in HepG2 cells.
    Gorgani-Firuzjaee S, Khatami S, Adeli K, Meshkani R.
    Biochem Biophys Res Commun; 2015 Sep 04; 464(4):1028-1033. PubMed ID: 26188518
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  • 2. SH2 domain-containing inositol 5-phosphatase (SHIP2) inhibition ameliorates high glucose-induced de-novo lipogenesis and VLDL production through regulating AMPK/mTOR/SREBP1 pathway and ROS production in HepG2 cells.
    Gorgani-Firuzjaee S, Meshkani R.
    Free Radic Biol Med; 2015 Dec 04; 89():679-89. PubMed ID: 26456051
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  • 3. Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins.
    Qiu W, Federico L, Naples M, Avramoglu RK, Meshkani R, Zhang J, Tsai J, Hussain M, Dai K, Iqbal J, Kontos CD, Horie Y, Suzuki A, Adeli K.
    Hepatology; 2008 Dec 04; 48(6):1799-809. PubMed ID: 19026012
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  • 7. Membrane localization of Src homology 2-containing inositol 5'-phosphatase 2 via Shc association is required for the negative regulation of insulin signaling in Rat1 fibroblasts overexpressing insulin receptors.
    Ishihara H, Sasaoka T, Ishiki M, Wada T, Hori H, Kagawa S, Kobayashi M.
    Mol Endocrinol; 2002 Oct 04; 16(10):2371-81. PubMed ID: 12351701
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  • 8. Overexpression of SH2-containing inositol phosphatase 2 results in negative regulation of insulin-induced metabolic actions in 3T3-L1 adipocytes via its 5'-phosphatase catalytic activity.
    Wada T, Sasaoka T, Funaki M, Hori H, Murakami S, Ishiki M, Haruta T, Asano T, Ogawa W, Ishihara H, Kobayashi M.
    Mol Cell Biol; 2001 Mar 04; 21(5):1633-46. PubMed ID: 11238900
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  • 9. Impact of the liver-specific expression of SHIP2 (SH2-containing inositol 5'-phosphatase 2) on insulin signaling and glucose metabolism in mice.
    Fukui K, Wada T, Kagawa S, Nagira K, Ikubo M, Ishihara H, Kobayashi M, Sasaoka T.
    Diabetes; 2005 Jul 04; 54(7):1958-67. PubMed ID: 15983195
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  • 10. Molecular cloning of rat SH2-containing inositol phosphatase 2 (SHIP2) and its role in the regulation of insulin signaling.
    Ishihara H, Sasaoka T, Hori H, Wada T, Hirai H, Haruta T, Langlois WJ, Kobayashi M.
    Biochem Biophys Res Commun; 1999 Jun 24; 260(1):265-72. PubMed ID: 10381377
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  • 12. Normalization of prandial blood glucose and improvement of glucose tolerance by liver-specific inhibition of SH2 domain containing inositol phosphatase 2 (SHIP2) in diabetic KKAy mice: SHIP2 inhibition causes insulin-mimetic effects on glycogen metabolism, gluconeogenesis, and glycolysis.
    Grempler R, Zibrova D, Schoelch C, van Marle A, Rippmann JF, Redemann N.
    Diabetes; 2007 Sep 24; 56(9):2235-41. PubMed ID: 17596404
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  • 16. SH2-containing inositol phosphatase 2 negatively regulates insulin-induced glycogen synthesis in L6 myotubes.
    Sasaoka T, Hori H, Wada T, Ishiki M, Haruta T, Ishihara H, Kobayashi M.
    Diabetologia; 2001 Oct 24; 44(10):1258-67. PubMed ID: 11692174
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  • 17. Inflammatory NF-kappaB activation promotes hepatic apolipoprotein B100 secretion: evidence for a link between hepatic inflammation and lipoprotein production.
    Tsai J, Zhang R, Qiu W, Su Q, Naples M, Adeli K.
    Am J Physiol Gastrointest Liver Physiol; 2009 Jun 24; 296(6):G1287-98. PubMed ID: 19342510
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  • 18. The association between the SH2-containing inositol polyphosphate 5-Phosphatase 2 (SHIP2) and the adaptor protein APS has an impact on biochemical properties of both partners.
    Onnockx S, De Schutter J, Blockmans M, Xie J, Jacobs C, Vanderwinden JM, Erneux C, Pirson I.
    J Cell Physiol; 2008 Jan 24; 214(1):260-72. PubMed ID: 17620296
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  • 19. AUP1 (Ancient Ubiquitous Protein 1) Is a Key Determinant of Hepatic Very-Low-Density Lipoprotein Assembly and Secretion.
    Zhang J, Zamani M, Thiele C, Taher J, Amir Alipour M, Yao Z, Adeli K.
    Arterioscler Thromb Vasc Biol; 2017 Apr 24; 37(4):633-642. PubMed ID: 28183703
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  • 20. The SH2 domain containing inositol 5-phosphatase SHIP2 controls phosphatidylinositol 3,4,5-trisphosphate levels in CHO-IR cells stimulated by insulin.
    Blero D, De Smedt F, Pesesse X, Paternotte N, Moreau C, Payrastre B, Erneux C.
    Biochem Biophys Res Commun; 2001 Apr 06; 282(3):839-43. PubMed ID: 11401540
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