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Journal Abstract Search

181 related items for PubMed ID: 26197159

  • 1. Synthesis of new 4-phenylpyrimidine-2(1H)-thiones and their potency to inhibit COX-1 and COX-2.
    Seebacher W, Faist J, Presser A, Weis R, Saf R, Kaserer T, Temml V, Schuster D, Ortmann S, Otto N, Bauer R.
    Eur J Med Chem; 2015 Aug 28; 101():552-9. PubMed ID: 26197159
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and evaluation of dithiolethiones as novel cyclooxygenase inhibitors.
    Zanatta SD, Manallack DT, Jarrott B, Williams SJ.
    Bioorg Med Chem Lett; 2009 Jan 15; 19(2):459-61. PubMed ID: 19056264
    [Abstract] [Full Text] [Related]

  • 3. Design, synthesis and evaluation of newer 5,6-dihydropyrimidine-2(1H)-thiones as GABA-AT inhibitors for anticonvulsant potential.
    Sahu M, Siddiqui N, Iqbal R, Sharma V, Wakode S.
    Bioorg Chem; 2017 Oct 15; 74():166-178. PubMed ID: 28806600
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of 2,3-diaryl-1,3-thiazolidine-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.
    Zarghi A, Najafnia L, Daraee B, Dadrass OG, Hedayati M.
    Bioorg Med Chem Lett; 2007 Oct 15; 17(20):5634-7. PubMed ID: 17822894
    [Abstract] [Full Text] [Related]

  • 5. New pyrimidines and triazolopyrimidines as antiproliferative and antioxidants with cyclooxygenase-1/2 inhibitory potential.
    Omar AM, Abd El Razik HA, Hazzaa AA, El-Attar MA, El Demellawy MA, Abdel Wahab AE, El Hawash SA.
    Future Med Chem; 2019 Jul 15; 11(13):1583-1603. PubMed ID: 31469327
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis, biological evaluation and molecular modeling of dihydropyrazole sulfonamide derivatives as potential COX-1/COX-2 inhibitors.
    Chen Z, Wang ZC, Yan XQ, Wang PF, Lu XY, Chen LW, Zhu HL, Zhang HW.
    Bioorg Med Chem Lett; 2015 May 01; 25(9):1947-51. PubMed ID: 25866240
    [Abstract] [Full Text] [Related]

  • 7. Synthesis, anti-inflammatory activity, and molecular docking studies of some novel Mannich bases of the 1,3,4-oxadiazole-2(3H)-thione scaffold.
    Ozyazici T, Gurdal EE, Orak D, Sipahi H, Ercetin T, Gulcan HO, Koksal M.
    Arch Pharm (Weinheim); 2020 Jul 01; 353(7):e2000061. PubMed ID: 32319141
    [Abstract] [Full Text] [Related]

  • 8. Graphite catalyzed solvent free synthesis of dihydropyrimidin-2(1H)-ones/thiones and their antidiabetic activity.
    Dhumaskar KL, Meena SN, Ghadi SC, Tilve SG.
    Bioorg Med Chem Lett; 2014 Jul 01; 24(13):2897-9. PubMed ID: 24835627
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and in-silico studies of some diaryltriazole derivatives as potential cyclooxygenase inhibitors.
    Radwan AA, elTahir KE.
    Arch Pharm Res; 2013 May 01; 36(5):553-63. PubMed ID: 23479193
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study.
    Abdel-Aziz AA, ElTahir KE, Asiri YA.
    Eur J Med Chem; 2011 May 01; 46(5):1648-55. PubMed ID: 21388719
    [Abstract] [Full Text] [Related]

  • 11. Diarylheterocycle core ring features effect in selective COX-1 inhibition.
    Perrone MG, Vitale P, Malerba P, Altomare A, Rizzi R, Lavecchia A, Di Giovanni C, Novellino E, Scilimati A.
    ChemMedChem; 2012 Apr 01; 7(4):629-41. PubMed ID: 22278975
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, biological evaluation and molecular modeling study of pyrazole derivatives as selective COX-2 inhibitors and anti-inflammatory agents.
    Tewari AK, Singh VP, Yadav P, Gupta G, Singh A, Goel RK, Shinde P, Mohan CG.
    Bioorg Chem; 2014 Oct 01; 56():8-15. PubMed ID: 24893208
    [Abstract] [Full Text] [Related]

  • 13. In vitro COX-1 and COX-2 enzyme inhibitory activities of iridoids from Penstemon barbatus, Castilleja tenuiflora, Cresentia alata and Vitex mollis.
    Ramírez-Cisneros MÁ, Rios MY, Aguilar-Guadarrama AB, Rao PP, Aburto-Amar R, Rodríguez-López V.
    Bioorg Med Chem Lett; 2015 Oct 15; 25(20):4505-8. PubMed ID: 26351040
    [Abstract] [Full Text] [Related]

  • 14. Synthesis of three 18F-labelled cyclooxygenase-2 (COX-2) inhibitors based on a pyrimidine scaffold.
    Tietz O, Sharma SK, Kaur J, Way J, Marshall A, Wuest M, Wuest F.
    Org Biomol Chem; 2013 Dec 14; 11(46):8052-64. PubMed ID: 24145766
    [Abstract] [Full Text] [Related]

  • 15. Cyclooxygenase-1 and cyclooxygenase-2 inhibition of novel 1,2-disubstituted imidazoles.
    Handler N, Jaeger W, Kuen-Krismer B, Erker T.
    Arch Pharm (Weinheim); 2005 Dec 14; 338(12):602-4. PubMed ID: 16353278
    [Abstract] [Full Text] [Related]

  • 16. Synthesis, biological evaluation and molecular modeling of novel thienopyrimidinone and triazolothienopyrimidinone derivatives as dual anti-inflammatory antimicrobial agents.
    Bekhit AA, Farghaly AM, Shafik RM, Elsemary MMA, Bekhit AEA, Guemei AA, El-Shoukrofy MS, Ibrahim TM.
    Bioorg Chem; 2018 Apr 14; 77():38-46. PubMed ID: 29328997
    [Abstract] [Full Text] [Related]

  • 17. COX-1/COX-2 inhibition activities and molecular docking study of newly designed and synthesized pyrrolo[3,4-c]pyrrole Mannich bases.
    Redzicka A, Szczukowski Ł, Kochel A, Wiatrak B, Gębczak K, Czyżnikowska Ż.
    Bioorg Med Chem; 2019 Sep 01; 27(17):3918-3928. PubMed ID: 31345747
    [Abstract] [Full Text] [Related]

  • 18. Divergent synthesis and evaluation of inhibitory activities against cyclooxygenases-1 and -2 of natural withasomnines and analogues.
    Usami Y, Watanabe R, Fujino Y, Shibano M, Ishida C, Yoneyama H, Harusawa S, Ichikawa H.
    Chem Pharm Bull (Tokyo); 2012 Sep 01; 60(12):1550-60. PubMed ID: 23207635
    [Abstract] [Full Text] [Related]

  • 19. Design and synthesis of new 1,3-benzthiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.
    Zarghi A, Zebardast T, Daraie B, Hedayati M.
    Bioorg Med Chem; 2009 Aug 01; 17(15):5369-73. PubMed ID: 19596198
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of new pyrazolone-pyridazine conjugates as anti-inflammatory and analgesic agents.
    Khalil NA, Ahmed EM, Mohamed KO, Nissan YM, Zaitone SA.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2080-9. PubMed ID: 24631365
    [Abstract] [Full Text] [Related]

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