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318 related items for PubMed ID: 26208883

  • 1. Differentiation and apoptosis induction by lovastatin and γ-tocotrienol in HL-60 cells via Ras/ERK/NF-κB and Ras/Akt/NF-κB signaling dependent down-regulation of glyoxalase 1 and HMG-CoA reductase.
    Chen CC, Liu TY, Huang SP, Ho CT, Huang TC.
    Cell Signal; 2015 Nov; 27(11):2182-90. PubMed ID: 26208883
    [Abstract] [Full Text] [Related]

  • 2. Peroxisome proliferator-activated receptor γ down-regulation mediates the inhibitory effect of d-δ-tocotrienol on the differentiation of murine 3T3-F442A preadipocytes.
    Torabi S, Yeganehjoo H, Shen CL, Mo H.
    Nutr Res; 2016 Dec; 36(12):1345-1352. PubMed ID: 27884413
    [Abstract] [Full Text] [Related]

  • 3. Gamma-tocotrienol inhibits nuclear factor-kappaB signaling pathway through inhibition of receptor-interacting protein and TAK1 leading to suppression of antiapoptotic gene products and potentiation of apoptosis.
    Ahn KS, Sethi G, Krishnan K, Aggarwal BB.
    J Biol Chem; 2007 Jan 05; 282(1):809-20. PubMed ID: 17114179
    [Abstract] [Full Text] [Related]

  • 4. Tocotrienols potentiate lovastatin-mediated growth suppression in vitro and in vivo.
    McAnally JA, Gupta J, Sodhani S, Bravo L, Mo H.
    Exp Biol Med (Maywood); 2007 Apr 05; 232(4):523-31. PubMed ID: 17392488
    [Abstract] [Full Text] [Related]

  • 5. Lycopene induces cell growth inhibition by altering mevalonate pathway and Ras signaling in cancer cell lines.
    Palozza P, Colangelo M, Simone R, Catalano A, Boninsegna A, Lanza P, Monego G, Ranelletti FO.
    Carcinogenesis; 2010 Oct 05; 31(10):1813-21. PubMed ID: 20699249
    [Abstract] [Full Text] [Related]

  • 6. Differential sensitivity of various pediatric cancers and squamous cell carcinomas to lovastatin-induced apoptosis: therapeutic implications.
    Dimitroulakos J, Ye LY, Benzaquen M, Moore MJ, Kamel-Reid S, Freedman MH, Yeger H, Penn LZ.
    Clin Cancer Res; 2001 Jan 05; 7(1):158-67. PubMed ID: 11205904
    [Abstract] [Full Text] [Related]

  • 7. Synergistic antiproliferative effects of gamma-tocotrienol and statin treatment on mammary tumor cells.
    Wali VB, Sylvester PW.
    Lipids; 2007 Dec 05; 42(12):1113-23. PubMed ID: 17701065
    [Abstract] [Full Text] [Related]

  • 8. Lovastatin-induced proliferation inhibition and apoptosis in C6 glial cells.
    Choi JW, Jung SE.
    J Pharmacol Exp Ther; 1999 Apr 05; 289(1):572-9. PubMed ID: 10087052
    [Abstract] [Full Text] [Related]

  • 9. Gamma-tocotrienol reverses multidrug resistance of breast cancer cells with a mechanism distinct from that of atorvastatin.
    Ding Y, Peng Y, Deng L, Fan J, Huang B.
    J Steroid Biochem Mol Biol; 2017 Mar 05; 167():67-77. PubMed ID: 27864002
    [Abstract] [Full Text] [Related]

  • 10. Blockade of the Ras/Raf/ERK and Ras/PI3K/Akt Pathways by Monacolin K Reduces the Expression of GLO1 and Induces Apoptosis in U937 Cells.
    Chen CC, Wu ML, Ho CT, Huang TC.
    J Agric Food Chem; 2015 Feb 04; 63(4):1186-1195. PubMed ID: 25569448
    [Abstract] [Full Text] [Related]

  • 11. First evidence that γ-tocotrienol inhibits the growth of human gastric cancer and chemosensitizes it to capecitabine in a xenograft mouse model through the modulation of NF-κB pathway.
    Manu KA, Shanmugam MK, Ramachandran L, Li F, Fong CW, Kumar AP, Tan P, Sethi G.
    Clin Cancer Res; 2012 Apr 15; 18(8):2220-9. PubMed ID: 22351692
    [Abstract] [Full Text] [Related]

  • 12. Endoplasmic reticulum stress mediates gamma-tocotrienol-induced apoptosis in mammary tumor cells.
    Wali VB, Bachawal SV, Sylvester PW.
    Apoptosis; 2009 Nov 15; 14(11):1366-77. PubMed ID: 19771520
    [Abstract] [Full Text] [Related]

  • 13. Synergistic effect of combined treatment with gamma-tocotrienol and statin on human malignant mesothelioma cells.
    Tuerdi G, Ichinomiya S, Sato H, Siddig S, Suwa E, Iwata H, Yano T, Ueno K.
    Cancer Lett; 2013 Oct 01; 339(1):116-27. PubMed ID: 23879968
    [Abstract] [Full Text] [Related]

  • 14. Combined treatment of gamma-tocotrienol with statins induce mammary tumor cell cycle arrest in G1.
    Wali VB, Bachawal SV, Sylvester PW.
    Exp Biol Med (Maywood); 2009 Jun 01; 234(6):639-50. PubMed ID: 19359655
    [Abstract] [Full Text] [Related]

  • 15. Tocotrienols regulate cholesterol production in mammalian cells by post-transcriptional suppression of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
    Parker RA, Pearce BC, Clark RW, Gordon DA, Wright JJ.
    J Biol Chem; 1993 May 25; 268(15):11230-8. PubMed ID: 8388388
    [Abstract] [Full Text] [Related]

  • 16. Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling.
    Sun W, Wang Q, Chen B, Liu J, Liu H, Xu W.
    Br J Nutr; 2008 Jun 25; 99(6):1247-54. PubMed ID: 18081943
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of phosphoinositide 3 kinase-Akt (protein kinase B)-nuclear factor-kappa B pathway by lovastatin limits endothelial-monocyte cell interaction.
    Prasad R, Giri S, Nath N, Singh I, Singh AK.
    J Neurochem; 2005 Jul 25; 94(1):204-14. PubMed ID: 15953363
    [Abstract] [Full Text] [Related]

  • 18. Survivin down-regulation plays a crucial role in 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor-induced apoptosis in cancer.
    Kaneko R, Tsuji N, Asanuma K, Tanabe H, Kobayashi D, Watanabe N.
    J Biol Chem; 2007 Jul 06; 282(27):19273-81. PubMed ID: 17472962
    [Abstract] [Full Text] [Related]

  • 19. γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent.
    Rajendran P, Li F, Manu KA, Shanmugam MK, Loo SY, Kumar AP, Sethi G.
    Br J Pharmacol; 2011 May 06; 163(2):283-98. PubMed ID: 21198544
    [Abstract] [Full Text] [Related]

  • 20. Induction of apoptosis by lovastatin through activation of caspase-3 and DNase II in leukaemia HL-60 cells.
    Wang IK, Lin-Shiau SY, Lin JK.
    Pharmacol Toxicol; 2000 Feb 06; 86(2):83-91. PubMed ID: 10728920
    [Abstract] [Full Text] [Related]

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