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355 related items for PubMed ID: 26232616

  • 1. Ceramide generation during curcumin-induced apoptosis is controlled by crosstalk among Bcl-2, Bcl-xL, caspases and glutathione.
    Abdel Shakor AB, Atia M, Alshehri AS, Sobota A, Kwiatkowska K.
    Cell Signal; 2015 Nov; 27(11):2220-30. PubMed ID: 26232616
    [Abstract] [Full Text] [Related]

  • 2. Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation.
    Shakor AB, Atia M, Ismail IA, Alshehri A, El-Refaey H, Kwiatkowska K, Sobota A.
    Biochim Biophys Acta; 2014 Dec; 1841(12):1672-82. PubMed ID: 25240837
    [Abstract] [Full Text] [Related]

  • 3. Curcumin (diferuloylmethane) induces apoptosis through activation of caspase-8, BID cleavage and cytochrome c release: its suppression by ectopic expression of Bcl-2 and Bcl-xl.
    Anto RJ, Mukhopadhyay A, Denning K, Aggarwal BB.
    Carcinogenesis; 2002 Jan; 23(1):143-50. PubMed ID: 11756235
    [Abstract] [Full Text] [Related]

  • 4. Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it.
    Rashmi R, Kumar S, Karunagaran D.
    Carcinogenesis; 2004 Oct; 25(10):1867-77. PubMed ID: 15205359
    [Abstract] [Full Text] [Related]

  • 5. Molecular mechanisms of curcumin-induced cytotoxicity: induction of apoptosis through generation of reactive oxygen species, down-regulation of Bcl-XL and IAP, the release of cytochrome c and inhibition of Akt.
    Woo JH, Kim YH, Choi YJ, Kim DG, Lee KS, Bae JH, Min DS, Chang JS, Jeong YJ, Lee YH, Park JW, Kwon TK.
    Carcinogenesis; 2003 Jul; 24(7):1199-208. PubMed ID: 12807727
    [Abstract] [Full Text] [Related]

  • 6. Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cells.
    Sawada M, Nakashima S, Banno Y, Yamakawa H, Hayashi K, Takenaka K, Nishimura Y, Sakai N, Nozawa Y.
    Cell Death Differ; 2000 Sep; 7(9):761-72. PubMed ID: 11042671
    [Abstract] [Full Text] [Related]

  • 7. Increase of nuclear ceramide through caspase-3-dependent regulation of the "sphingomyelin cycle" in Fas-induced apoptosis.
    Watanabe M, Kitano T, Kondo T, Yabu T, Taguchi Y, Tashima M, Umehara H, Domae N, Uchiyama T, Okazaki T.
    Cancer Res; 2004 Feb 01; 64(3):1000-7. PubMed ID: 14871831
    [Abstract] [Full Text] [Related]

  • 8. Glutathione regulates caspase-dependent ceramide production and curcumin-induced apoptosis in human leukemic cells.
    Kizhakkayil J, Thayyullathil F, Chathoth S, Hago A, Patel M, Galadari S.
    Free Radic Biol Med; 2012 May 01; 52(9):1854-64. PubMed ID: 22387197
    [Abstract] [Full Text] [Related]

  • 9. Influence of Bax or Bcl-2 overexpression on the ceramide-dependent apoptotic pathway in glioma cells.
    Sawada M, Nakashima S, Banno Y, Yamakawa H, Takenaka K, Shinoda J, Nishimura Y, Sakai N, Nozawa Y.
    Oncogene; 2000 Jul 20; 19(31):3508-20. PubMed ID: 10918609
    [Abstract] [Full Text] [Related]

  • 10. Ectopic expression of Bcl-2 and Bcl-xL inhibits apoptosis induced by TNF-related apoptosis-inducing ligand (TRAIL) through suppression of caspases-8, 7, and 3 and BID cleavage in human acute myelogenous leukemia cell line HL-60.
    Lamothe B, Aggarwal BB.
    J Interferon Cytokine Res; 2002 Feb 20; 22(2):269-79. PubMed ID: 11911810
    [Abstract] [Full Text] [Related]

  • 11. Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.
    Rashmi R, Kumar S, Karunagaran D.
    Carcinogenesis; 2005 Apr 20; 26(4):713-23. PubMed ID: 15661804
    [Abstract] [Full Text] [Related]

  • 12. Distinct sites of action of Bcl-2 and Bcl-xL in the ceramide pathway of apoptosis.
    El-Assaad W, El-Sabban M, Awaraji C, Abboushi N, Dbaibo GS.
    Biochem J; 1998 Dec 15; 336 ( Pt 3)(Pt 3):735-41. PubMed ID: 9841888
    [Abstract] [Full Text] [Related]

  • 13. Overexpression of Bcl-2 or Bcl-xL inhibits Ara-C-induced CPP32/Yama protease activity and apoptosis of human acute myelogenous leukemia HL-60 cells.
    Ibrado AM, Huang Y, Fang G, Liu L, Bhalla K.
    Cancer Res; 1996 Oct 15; 56(20):4743-8. PubMed ID: 8840993
    [Abstract] [Full Text] [Related]

  • 14. N,N-dimethyl phytosphingosine induces caspase-8-dependent cytochrome c release and apoptosis through ROS generation in human leukemia cells.
    Kim BM, Choi YJ, Han Y, Yun YS, Hong SH.
    Toxicol Appl Pharmacol; 2009 Aug 15; 239(1):87-97. PubMed ID: 19481559
    [Abstract] [Full Text] [Related]

  • 15. Curcumin downregulates cell survival mechanisms in human prostate cancer cell lines.
    Mukhopadhyay A, Bueso-Ramos C, Chatterjee D, Pantazis P, Aggarwal BB.
    Oncogene; 2001 Nov 15; 20(52):7597-609. PubMed ID: 11753638
    [Abstract] [Full Text] [Related]

  • 16. Curcumin-induced apoptosis in human leukemia cell HL-60 is associated with inhibition of telomerase activity.
    Mukherjee Nee Chakraborty S, Ghosh U, Bhattacharyya NP, Bhattacharya RK, Dey S, Roy M.
    Mol Cell Biochem; 2007 Mar 15; 297(1-2):31-9. PubMed ID: 17096185
    [Abstract] [Full Text] [Related]

  • 17. Curcumin-induced apoptosis in PC3 prostate carcinoma cells is caspase-independent and involves cellular ceramide accumulation and damage to mitochondria.
    Hilchie AL, Furlong SJ, Sutton K, Richardson A, Robichaud MR, Giacomantonio CA, Ridgway ND, Hoskin DW.
    Nutr Cancer; 2010 Mar 15; 62(3):379-89. PubMed ID: 20358476
    [Abstract] [Full Text] [Related]

  • 18. Stichoposide C induces apoptosis through the generation of ceramide in leukemia and colorectal cancer cells and shows in vivo antitumor activity.
    Yun SH, Park ES, Shin SW, Na YW, Han JY, Jeong JS, Shastina VV, Stonik VA, Park JI, Kwak JY.
    Clin Cancer Res; 2012 Nov 01; 18(21):5934-48. PubMed ID: 23132899
    [Abstract] [Full Text] [Related]

  • 19. Overexpression of bcl-2 or bcl-XL fails to inhibit apoptosis mediated by a novel retinoid.
    Fontana JA, Sun RJ, Rishi AK, Dawson MI, Ordónez JV, Zhang Y, Tschang SH, Bhalla K, Han Z, Wyche J, Poirer G, Sheikh MS, Shroot B, Reichert U.
    Oncol Res; 1998 Nov 01; 10(6):313-24. PubMed ID: 9848102
    [Abstract] [Full Text] [Related]

  • 20. C6 ceramide potentiates curcumin-induced cell death and apoptosis in melanoma cell lines in vitro.
    Yu T, Li J, Sun H.
    Cancer Chemother Pharmacol; 2010 Oct 01; 66(5):999-1003. PubMed ID: 20521051
    [Abstract] [Full Text] [Related]

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