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1452 related items for PubMed ID: 26246196

  • 1. Piperlongumine induces apoptosis and autophagy in human lung cancer cells through inhibition of PI3K/Akt/mTOR pathway.
    Wang F, Mao Y, You Q, Hua D, Cai D.
    Int J Immunopathol Pharmacol; 2015 Sep; 28(3):362-73. PubMed ID: 26246196
    [Abstract] [Full Text] [Related]

  • 2. Arenobufagin, a natural bufadienolide from toad venom, induces apoptosis and autophagy in human hepatocellular carcinoma cells through inhibition of PI3K/Akt/mTOR pathway.
    Zhang DM, Liu JS, Deng LJ, Chen MF, Yiu A, Cao HH, Tian HY, Fung KP, Kurihara H, Pan JX, Ye WC.
    Carcinogenesis; 2013 Jun; 34(6):1331-42. PubMed ID: 23393227
    [Abstract] [Full Text] [Related]

  • 3. Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway.
    Liu F, Gao S, Yang Y, Zhao X, Fan Y, Ma W, Yang D, Yang A, Yu Y.
    Oncol Rep; 2018 Mar; 39(3):1523-1531. PubMed ID: 29328421
    [Abstract] [Full Text] [Related]

  • 4. Licochalcone A induces autophagy through PI3K/Akt/mTOR inactivation and autophagy suppression enhances Licochalcone A-induced apoptosis of human cervical cancer cells.
    Tsai JP, Lee CH, Ying TH, Lin CL, Lin CL, Hsueh JT, Hsieh YH.
    Oncotarget; 2015 Oct 06; 6(30):28851-66. PubMed ID: 26311737
    [Abstract] [Full Text] [Related]

  • 5. Piperlongumine, a piper alkaloid targets Ras/PI3K/Akt/mTOR signaling axis to inhibit tumor cell growth and proliferation in DMH/DSS induced experimental colon cancer.
    Kumar S, Agnihotri N.
    Biomed Pharmacother; 2019 Jan 06; 109():1462-1477. PubMed ID: 30551398
    [Abstract] [Full Text] [Related]

  • 6. Luteoloside induces G0/G1 arrest and pro-death autophagy through the ROS-mediated AKT/mTOR/p70S6K signalling pathway in human non-small cell lung cancer cell lines.
    Zhou M, Shen S, Zhao X, Gong X.
    Biochem Biophys Res Commun; 2017 Dec 09; 494(1-2):263-269. PubMed ID: 29024631
    [Abstract] [Full Text] [Related]

  • 7. Piperlongumine promotes autophagy via inhibition of Akt/mTOR signalling and mediates cancer cell death.
    Makhov P, Golovine K, Teper E, Kutikov A, Mehrazin R, Corcoran A, Tulin A, Uzzo RG, Kolenko VM.
    Br J Cancer; 2014 Feb 18; 110(4):899-907. PubMed ID: 24434432
    [Abstract] [Full Text] [Related]

  • 8. Cabazitaxel-induced autophagy via the PI3K/Akt/mTOR pathway contributes to A549 cell death.
    Huo R, Wang L, Liu P, Zhao Y, Zhang C, Bai B, Liu X, Shi C, Wei S, Zhang H.
    Mol Med Rep; 2016 Oct 18; 14(4):3013-20. PubMed ID: 27572899
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of Autophagy Increases Proliferation Inhibition and Apoptosis Induced by the PI3K/mTOR Inhibitor NVP-BEZ235 in Breast Cancer Cells.
    Ji Y, Di W, Yang Q, Lu Z, Cai W, Wu J.
    Clin Lab; 2015 Oct 18; 61(8):1043-51. PubMed ID: 26427150
    [Abstract] [Full Text] [Related]

  • 10. PDB-1 from Potentilla discolor Bunge induces apoptosis and autophagy by downregulating the PI3K/Akt/mTOR signaling pathway in A549 cells.
    Zhang RR, Meng NN, Liu C, Li KL, Wang MX, Lv ZB, Chen SY, Guo X, Wang XK, Wang Q, Sun JY.
    Biomed Pharmacother; 2020 Sep 18; 129():110378. PubMed ID: 32544818
    [Abstract] [Full Text] [Related]

  • 11. Piperlongumine, an alkaloid causes inhibition of PI3 K/Akt/mTOR signaling axis to induce caspase-dependent apoptosis in human triple-negative breast cancer cells.
    Shrivastava S, Kulkarni P, Thummuri D, Jeengar MK, Naidu VG, Alvala M, Redddy GB, Ramakrishna S.
    Apoptosis; 2014 Jul 18; 19(7):1148-64. PubMed ID: 24729100
    [Abstract] [Full Text] [Related]

  • 12. Puquitinib mesylate (XC-302) induces autophagy via inhibiting the PI3K/AKT/mTOR signaling pathway in nasopharyngeal cancer cells.
    Wang KF, Yang H, Jiang WQ, Li S, Cai YC.
    Int J Mol Med; 2015 Dec 18; 36(6):1556-62. PubMed ID: 26499488
    [Abstract] [Full Text] [Related]

  • 13. Anti-tumor efficacy of phellamurin in osteosarcoma cells: Involvement of the PI3K/AKT/mTOR pathway.
    Zhang H, Jiang H, Zhang H, Liu J, Hu X, Chen L.
    Eur J Pharmacol; 2019 Sep 05; 858():172477. PubMed ID: 31228450
    [Abstract] [Full Text] [Related]

  • 14. PM02734 (elisidepsin) induces caspase-independent cell death associated with features of autophagy, inhibition of the Akt/mTOR signaling pathway, and activation of death-associated protein kinase.
    Ling YH, Aracil M, Zou Y, Yuan Z, Lu B, Jimeno J, Cuervo AM, Perez-Soler R.
    Clin Cancer Res; 2011 Aug 15; 17(16):5353-66. PubMed ID: 21690574
    [Abstract] [Full Text] [Related]

  • 15. Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway.
    Rong L, Li Z, Leng X, Li H, Ma Y, Chen Y, Song F.
    Biomed Pharmacother; 2020 Feb 15; 122():109726. PubMed ID: 31918283
    [Abstract] [Full Text] [Related]

  • 16. Pro-apoptotic and pro-autophagic effects of the Aurora kinase A inhibitor alisertib (MLN8237) on human osteosarcoma U-2 OS and MG-63 cells through the activation of mitochondria-mediated pathway and inhibition of p38 MAPK/PI3K/Akt/mTOR signaling pathway.
    Niu NK, Wang ZL, Pan ST, Ding HQ, Au GH, He ZX, Zhou ZW, Xiao G, Yang YX, Zhang X, Yang T, Chen XW, Qiu JX, Zhou SF.
    Drug Des Devel Ther; 2015 Feb 15; 9():1555-84. PubMed ID: 25792811
    [Abstract] [Full Text] [Related]

  • 17. Delicaflavone induces autophagic cell death in lung cancer via Akt/mTOR/p70S6K signaling pathway.
    Sui Y, Yao H, Li S, Jin L, Shi P, Li Z, Wang G, Lin S, Wu Y, Li Y, Huang L, Liu Q, Lin X.
    J Mol Med (Berl); 2017 Mar 15; 95(3):311-322. PubMed ID: 27838742
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of mitotic Aurora kinase A by alisertib induces apoptosis and autophagy of human gastric cancer AGS and NCI-N78 cells.
    Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Wang NJ, Zhao RJ, Zhou SF.
    Drug Des Devel Ther; 2015 Mar 15; 9():487-508. PubMed ID: 25609923
    [Abstract] [Full Text] [Related]

  • 19. Danusertib, a potent pan-Aurora kinase and ABL kinase inhibitor, induces cell cycle arrest and programmed cell death and inhibits epithelial to mesenchymal transition involving the PI3K/Akt/mTOR-mediated signaling pathway in human gastric cancer AGS and NCI-N78 cells.
    Yuan CX, Zhou ZW, Yang YX, He ZX, Zhang X, Wang D, Yang T, Pan SY, Chen XW, Zhou SF.
    Drug Des Devel Ther; 2015 Mar 15; 9():1293-318. PubMed ID: 25767376
    [Abstract] [Full Text] [Related]

  • 20. A novel hybrid of 3-benzyl coumarin seco-B-ring derivative and phenylsulfonylfuroxan induces apoptosis and autophagy in non-small-cell lung cancer.
    Dong M, Ye T, Bi Y, Wang Q, Kuerban K, Li J, Feng M, Wang K, Chen Y, Ye L.
    Phytomedicine; 2019 Jan 15; 52():79-88. PubMed ID: 30599915
    [Abstract] [Full Text] [Related]

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