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344 related items for PubMed ID: 26252954

  • 1. High-Throughput Assay Development for Cystine-Glutamate Antiporter (xc-) Highlights Faster Cystine Uptake than Glutamate Release in Glioma Cells.
    Thomas AG, Sattler R, Tendyke K, Loiacono KA, Hansen H, Sahni V, Hashizume Y, Rojas C, Slusher BS.
    PLoS One; 2015; 10(8):e0127785. PubMed ID: 26252954
    [Abstract] [Full Text] [Related]

  • 2. Compromised glutamate transport in human glioma cells: reduction-mislocalization of sodium-dependent glutamate transporters and enhanced activity of cystine-glutamate exchange.
    Ye ZC, Rothstein JD, Sontheimer H.
    J Neurosci; 1999 Dec 15; 19(24):10767-77. PubMed ID: 10594060
    [Abstract] [Full Text] [Related]

  • 3. Inhibition of cystine uptake disrupts the growth of primary brain tumors.
    Chung WJ, Lyons SA, Nelson GM, Hamza H, Gladson CL, Gillespie GY, Sontheimer H.
    J Neurosci; 2005 Aug 03; 25(31):7101-10. PubMed ID: 16079392
    [Abstract] [Full Text] [Related]

  • 4. Glial Glutamate Transporter-Mediated Plasticity: System xc-/xCT/SLC7A11 and EAAT1/2 in Brain Diseases.
    Dahlmanns M, Dahlmanns JK, Savaskan N, Steiner HH, Yakubov E.
    Front Biosci (Landmark Ed); 2023 Mar 20; 28(3):57. PubMed ID: 37005761
    [Abstract] [Full Text] [Related]

  • 5. The xc- cystine/glutamate antiporter as a potential therapeutic target for small-cell lung cancer: use of sulfasalazine.
    Guan J, Lo M, Dockery P, Mahon S, Karp CM, Buckley AR, Lam S, Gout PW, Wang YZ.
    Cancer Chemother Pharmacol; 2009 Aug 20; 64(3):463-72. PubMed ID: 19104813
    [Abstract] [Full Text] [Related]

  • 6. The EGF Receptor Promotes the Malignant Potential of Glioma by Regulating Amino Acid Transport System xc(-).
    Tsuchihashi K, Okazaki S, Ohmura M, Ishikawa M, Sampetrean O, Onishi N, Wakimoto H, Yoshikawa M, Seishima R, Iwasaki Y, Morikawa T, Abe S, Takao A, Shimizu M, Masuko T, Nagane M, Furnari FB, Akiyama T, Suematsu M, Baba E, Akashi K, Saya H, Nagano O.
    Cancer Res; 2016 May 15; 76(10):2954-63. PubMed ID: 26980765
    [Abstract] [Full Text] [Related]

  • 7. Epidermal growth factor receptor promotes glioma progression by regulating xCT and GluN2B-containing N-methyl-d-aspartate-sensitive glutamate receptor signaling.
    Suina K, Tsuchihashi K, Yamasaki J, Kamenori S, Shintani S, Hirata Y, Okazaki S, Sampetrean O, Baba E, Akashi K, Mitsuishi Y, Takahashi F, Takahashi K, Saya H, Nagano O.
    Cancer Sci; 2018 Dec 15; 109(12):3874-3882. PubMed ID: 30298963
    [Abstract] [Full Text] [Related]

  • 8. Dysregulated Glutamate Transporter SLC1A1 Propels Cystine Uptake via Xc- for Glutathione Synthesis in Lung Cancer.
    Guo W, Li K, Sun B, Xu D, Tong L, Yin H, Liao Y, Song H, Wang T, Jing B, Hu M, Liu S, Kuang Y, Ling J, Li Q, Wu Y, Wang Q, Yao F, Zhou BP, Lin SH, Deng J.
    Cancer Res; 2021 Feb 01; 81(3):552-566. PubMed ID: 33229341
    [Abstract] [Full Text] [Related]

  • 9. Functional effects of TrkA inhibition on system xC--mediated glutamate release and cancer-induced bone pain.
    Miladinovic T, Ungard RG, Linher-Melville K, Popovic S, Singh G.
    Mol Pain; 2018 Feb 01; 14():1744806918776467. PubMed ID: 29761734
    [Abstract] [Full Text] [Related]

  • 10. Glutamate, excitatory amino acid transporters, Xc- antiporter, glutamine synthetase, and gamma-glutamyltranspeptidase in human corneal epithelium.
    Langford MP, Redmond P, Chanis R, Misra RP, Redens TB.
    Curr Eye Res; 2010 Mar 01; 35(3):202-11. PubMed ID: 20373878
    [Abstract] [Full Text] [Related]

  • 11. Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc antiporter system.
    Mawatari K, Yasui Y, Sugitani K, Takadera T, Kato S.
    Neuroscience; 1996 Jul 01; 73(1):201-8. PubMed ID: 8783242
    [Abstract] [Full Text] [Related]

  • 12. Autocrine glutamate signaling promotes glioma cell invasion.
    Lyons SA, Chung WJ, Weaver AK, Ogunrinu T, Sontheimer H.
    Cancer Res; 2007 Oct 01; 67(19):9463-71. PubMed ID: 17909056
    [Abstract] [Full Text] [Related]

  • 13. Dissection of mitogenic and neurodegenerative actions of cystine and glutamate in malignant gliomas.
    Savaskan NE, Seufert S, Hauke J, Tränkle C, Eyüpoglu IY, Hahnen E.
    Oncogene; 2011 Jan 06; 30(1):43-53. PubMed ID: 20802520
    [Abstract] [Full Text] [Related]

  • 14. Identification, Expression, and Roles of the Cystine/Glutamate Antiporter in Ocular Tissues.
    Martis RM, Knight LJ, Donaldson PJ, Lim JC.
    Oxid Med Cell Longev; 2020 Jan 06; 2020():4594606. PubMed ID: 32655769
    [Abstract] [Full Text] [Related]

  • 15. Thinking outside the cleft to understand synaptic activity: contribution of the cystine-glutamate antiporter (System xc-) to normal and pathological glutamatergic signaling.
    Bridges R, Lutgen V, Lobner D, Baker DA.
    Pharmacol Rev; 2012 Jul 06; 64(3):780-802. PubMed ID: 22759795
    [Abstract] [Full Text] [Related]

  • 16. Hydrogen peroxide triggers an increase in cell surface expression of system xc- in cultured human glioma cells.
    Chase LA, VerHeulen Kleyn M, Schiller N, King AG, Flores G, Engelsman SB, Bowles C, Smith SL, Robinson AE, Rothstein J.
    Neurochem Int; 2020 Mar 06; 134():104648. PubMed ID: 31874187
    [Abstract] [Full Text] [Related]

  • 17. The Lathyrus excitotoxin beta-N-oxalyl-L-alpha,beta-diaminopropionic acid is a substrate of the L-cystine/L-glutamate exchanger system xc-.
    Warren BA, Patel SA, Nunn PB, Bridges RJ.
    Toxicol Appl Pharmacol; 2004 Oct 15; 200(2):83-92. PubMed ID: 15476861
    [Abstract] [Full Text] [Related]

  • 18. Pharmacogenomic approach reveals a role for the x(c)- cystine/glutamate antiporter in growth and celastrol resistance of glioma cell lines.
    Pham AN, Blower PE, Alvarado O, Ravula R, Gout PW, Huang Y.
    J Pharmacol Exp Ther; 2010 Mar 15; 332(3):949-58. PubMed ID: 20007406
    [Abstract] [Full Text] [Related]

  • 19. PET Imaging of L-Type Amino Acid Transporter (LAT1) and Cystine-Glutamate Antiporter (xc-) with [18F]FDOPA and [18F]FSPG in Breast Cancer Models.
    Krys D, Mattingly S, Glubrecht D, Wuest M, Wuest F.
    Mol Imaging Biol; 2020 Dec 15; 22(6):1562-1571. PubMed ID: 32789819
    [Abstract] [Full Text] [Related]

  • 20. A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion.
    Kato S, Negishi K, Mawatari K, Kuo CH.
    Neuroscience; 1992 Jun 15; 48(4):903-14. PubMed ID: 1352866
    [Abstract] [Full Text] [Related]

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