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344 related items for PubMed ID: 26255760
1. A breakthrough novel method to resolve the drug and target interference problem in immunogenicity assays. Zoghbi J, Xu Y, Grabert R, Theobald V, Richards S. J Immunol Methods; 2015 Nov; 426():62-9. PubMed ID: 26255760 [Abstract] [Full Text] [Related]
2. Evaluation of a generic immunoassay with drug tolerance to detect immune complexes in serum samples from cynomolgus monkeys after administration of human antibodies. Stubenrauch K, Wessels U, Essig U, Vogel R, Schleypen J. J Pharm Biomed Anal; 2010 Jun 05; 52(2):249-54. PubMed ID: 20083366 [Abstract] [Full Text] [Related]
3. Detection of drug specific circulating immune complexes from in vivo cynomolgus monkey serum samples. Pierog P, Krishna M, Yamniuk A, Chauhan A, DeSilva B. J Immunol Methods; 2015 Jan 05; 416():124-36. PubMed ID: 25462536 [Abstract] [Full Text] [Related]
4. A novel method for the detection of antibodies to adalimumab in the presence of drug reveals "hidden" immunogenicity in rheumatoid arthritis patients. van Schouwenburg PA, Bartelds GM, Hart MH, Aarden L, Wolbink GJ, Wouters D. J Immunol Methods; 2010 Oct 31; 362(1-2):82-8. PubMed ID: 20833178 [Abstract] [Full Text] [Related]
5. Solution ELISA as a platform of choice for development of robust, drug tolerant immunogenicity assays in support of drug development. Mikulskis A, Yeung D, Subramanyam M, Amaravadi L. J Immunol Methods; 2011 Feb 28; 365(1-2):38-49. PubMed ID: 21130095 [Abstract] [Full Text] [Related]
6. Differential effect of drug interference in immunogenicity assays. Hart MH, de Vrieze H, Wouters D, Wolbink GJ, Killestein J, de Groot ER, Aarden LA, Rispens T. J Immunol Methods; 2011 Sep 30; 372(1-2):196-203. PubMed ID: 21824477 [Abstract] [Full Text] [Related]
7. A systematic study of the effect of low pH acid treatment on anti-drug antibodies specific for a domain antibody therapeutic: Impact on drug tolerance, assay sensitivity and post-validation method assessment of ADA in clinical serum samples. Kavita U, Duo J, Crawford SM, Liu R, Valcin J, Gleason C, Dong H, Gadkari S, Dodge RW, Pillutla RC, DeSilva BS. J Immunol Methods; 2017 Sep 30; 448():91-104. PubMed ID: 28625864 [Abstract] [Full Text] [Related]
8. Detection of low-affinity anti-drug antibodies and improved drug tolerance in immunogenicity testing by Octet(®) biolayer interferometry. Li J, Schantz A, Schwegler M, Shankar G. J Pharm Biomed Anal; 2011 Jan 25; 54(2):286-94. PubMed ID: 20869832 [Abstract] [Full Text] [Related]
9. Development of a biosensor-based immunogenicity assay capable of blocking soluble drug target interference. Weeraratne DK, Lofgren J, Dinnogen S, Swanson SJ, Zhong ZD. J Immunol Methods; 2013 Oct 31; 396(1-2):44-55. PubMed ID: 23933325 [Abstract] [Full Text] [Related]
10. Systematic comparison of drug-tolerant assays for anti-drug antibodies in a cohort of adalimumab-treated rheumatoid arthritis patients. Bloem K, van Leeuwen A, Verbeek G, Nurmohamed MT, Wolbink GJ, van der Kleij D, Rispens T. J Immunol Methods; 2015 Mar 31; 418():29-38. PubMed ID: 25637408 [Abstract] [Full Text] [Related]
11. An electrochemiluminescence (ECL)-based assay for the specific detection of anti-drug antibodies of the IgE isotype. Wu Y, Liu X, Chen Y, Woods R, Lee N, Yang H, Chowdhury P, Roskos LK, White WI. J Pharm Biomed Anal; 2013 Dec 31; 86():73-81. PubMed ID: 23988731 [Abstract] [Full Text] [Related]
12. Generic anti-drug antibody assay with drug tolerance in serum samples from mice exposed to human antibodies. Stubenrauch K, Mackeben K, Vogel R, Heinrich J. Anal Biochem; 2012 Nov 15; 430(2):193-9. PubMed ID: 22935295 [Abstract] [Full Text] [Related]
13. Improvement of drug tolerance in immunogenicity testing by acid treatment on Biacore. Sickert D, Kroeger K, Zickler C, Chokote E, Winkler B, Grenet JM, Legay F, Zaar A. J Immunol Methods; 2008 May 20; 334(1-2):29-36. PubMed ID: 18304570 [Abstract] [Full Text] [Related]
14. Strategies to estimate and improve drug tolerance in anti-drug antibody assays. Bütikofer L, Lemaillet G, Faust H. Bioanalysis; 2012 Aug 20; 4(16):1999-2012. PubMed ID: 22946916 [Abstract] [Full Text] [Related]
15. Detection of antidrug antibodies against human therapeutic antibodies lacking Fc-effector functions by usage of soluble Fcγ receptor I. Wessels U, Poehler A, Moheysen-Zadeh M, Zadak M, Staack RF, Umana P, Heinrich J, Stubenrauch K. Bioanalysis; 2016 Oct 20; 8(20):2135-45. PubMed ID: 27582032 [Abstract] [Full Text] [Related]
16. Attribution of the discrepancy between ELISA and LC-MS/MS assay results of a PEGylated scaffold protein in post-dose monkey plasma samples due to the presence of anti-drug antibodies. Wang SJ, Wu ST, Gokemeijer J, Fura A, Krishna M, Morin P, Chen G, Price K, Wang-Iverson D, Olah T, Weiner R, Tymiak A, Jemal M. Anal Bioanal Chem; 2012 Jan 20; 402(3):1229-39. PubMed ID: 22130720 [Abstract] [Full Text] [Related]
17. A double antigen bridging immunogenicity ELISA for the detection of antibodies to polyethylene glycol polymers. Liu Y, Reidler H, Pan J, Milunic D, Qin D, Chen D, Vallejo YR, Yin R. J Pharmacol Toxicol Methods; 2011 Jan 20; 64(3):238-45. PubMed ID: 21827863 [Abstract] [Full Text] [Related]
18. A novel immunoassay to measure total serum lymphotoxin-α levels in the presence of an anti-LTα therapeutic antibody. Young J, Nguyen A, Qiu ZJ, Ying Y, Gao X, Reed C, Chuntharapai A, Deng R, Lutman J, Grogan J, Wong WL, DeForge L. J Immunol Methods; 2015 Sep 20; 424():91-9. PubMed ID: 26009247 [Abstract] [Full Text] [Related]
19. Drug Target Interference in Immunogenicity Assays: Recommendations and Mitigation Strategies. Zhong ZD, Clements-Egan A, Gorovits B, Maia M, Sumner G, Theobald V, Wu Y, Rajadhyaksha M. AAPS J; 2017 Nov 20; 19(6):1564-1575. PubMed ID: 29063411 [Abstract] [Full Text] [Related]
20. An innovative and highly drug-tolerant approach for detecting neutralizing antibodies directed to therapeutic antibodies. Sloan JH, Conway RG, Pottanat TG, Troutt JS, Higgs RE, Konrad RJ, Qian YW. Bioanalysis; 2016 Oct 20; 8(20):2157-68. PubMed ID: 27593891 [Abstract] [Full Text] [Related] Page: [Next] [New Search]