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Journal Abstract Search

332 related items for PubMed ID: 26256645

  • 1. Expanding the horizons of G protein-coupled receptor structure-based ligand discovery and optimization using homology models.
    Cavasotto CN, Palomba D.
    Chem Commun (Camb); 2015 Sep 14; 51(71):13576-94. PubMed ID: 26256645
    [Abstract] [Full Text] [Related]

  • 2. Modeling G protein-coupled receptors and their interactions with ligands.
    Costanzi S.
    Curr Opin Struct Biol; 2013 Apr 14; 23(2):185-90. PubMed ID: 23415855
    [Abstract] [Full Text] [Related]

  • 3. GPCR Homology Model Generation for Lead Optimization.
    Tautermann CS.
    Methods Mol Biol; 2018 Apr 14; 1705():115-131. PubMed ID: 29188560
    [Abstract] [Full Text] [Related]

  • 4. Strategies for designing GPCR-focused libraries and screening sets.
    Jimonet P, Jäger R.
    Curr Opin Drug Discov Devel; 2004 May 14; 7(3):325-33. PubMed ID: 15216936
    [Abstract] [Full Text] [Related]

  • 5. Structure versus function-The impact of computational methods on the discovery of specific GPCR-ligands.
    Bermudez M, Wolber G.
    Bioorg Med Chem; 2015 Jul 15; 23(14):3907-12. PubMed ID: 25828056
    [Abstract] [Full Text] [Related]

  • 6. Drug design strategies for targeting G-protein-coupled receptors.
    Klabunde T, Hessler G.
    Chembiochem; 2002 Oct 04; 3(10):928-44. PubMed ID: 12362358
    [Abstract] [Full Text] [Related]

  • 7. From heptahelical bundle to hits from the Haystack: structure-based virtual screening for GPCR ligands.
    Kooistra AJ, Roumen L, Leurs R, de Esch IJ, de Graaf C.
    Methods Enzymol; 2013 Oct 04; 522():279-336. PubMed ID: 23374191
    [Abstract] [Full Text] [Related]

  • 8. G-protein-coupled receptor-focused drug discovery using a target class platform approach.
    Heilker R, Wolff M, Tautermann CS, Bieler M.
    Drug Discov Today; 2009 Mar 04; 14(5-6):231-40. PubMed ID: 19121411
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  • 13. Identification of structural motifs critical for epstein-barr virus-induced molecule 2 function and homology modeling of the ligand docking site.
    Zhang L, Shih AY, Yang XV, Kuei C, Wu J, Deng X, Mani NS, Mirzadegan T, Sun S, Lovenberg TW, Liu C.
    Mol Pharmacol; 2012 Dec 04; 82(6):1094-103. PubMed ID: 22930711
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  • 14. Structure-based and fragment-based GPCR drug discovery.
    Andrews SP, Brown GA, Christopher JA.
    ChemMedChem; 2014 Feb 04; 9(2):256-75. PubMed ID: 24353016
    [Abstract] [Full Text] [Related]

  • 15. The GPCR crystallography boom: providing an invaluable source of structural information and expanding the scope of homology modeling.
    Costanzi S, Wang K.
    Adv Exp Med Biol; 2014 Feb 04; 796():3-13. PubMed ID: 24158798
    [Abstract] [Full Text] [Related]

  • 16. Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008.
    Michino M, Abola E, GPCR Dock 2008 participants, Brooks CL, Dixon JS, Moult J, Stevens RC.
    Nat Rev Drug Discov; 2009 Jun 04; 8(6):455-63. PubMed ID: 19461661
    [Abstract] [Full Text] [Related]

  • 17. The structure and dynamics of GPCR oligomers: a new focus in models of cell-signaling mechanisms and drug design.
    Filizola M, Weinstein H.
    Curr Opin Drug Discov Devel; 2005 Sep 04; 8(5):577-84. PubMed ID: 16159019
    [Abstract] [Full Text] [Related]

  • 18. Chemical Diversity in the G Protein-Coupled Receptor Superfamily.
    Vass M, Kooistra AJ, Yang D, Stevens RC, Wang MW, de Graaf C.
    Trends Pharmacol Sci; 2018 May 04; 39(5):494-512. PubMed ID: 29576399
    [Abstract] [Full Text] [Related]

  • 19. The 7 TM G-protein-coupled receptor target family.
    Jacoby E, Bouhelal R, Gerspacher M, Seuwen K.
    ChemMedChem; 2006 Aug 04; 1(8):761-82. PubMed ID: 16902930
    [Abstract] [Full Text] [Related]

  • 20. GPCR structures in drug design, emerging opportunities with new structures.
    Tautermann CS.
    Bioorg Med Chem Lett; 2014 Sep 01; 24(17):4073-9. PubMed ID: 25086683
    [Abstract] [Full Text] [Related]

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