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148 related items for PubMed ID: 26258875

  • 1. FV-429 induces apoptosis and inhibits glycolysis by inhibiting Akt-mediated phosphorylation of hexokinase II in MDA-MB-231 cells.
    Zhou Y, Lu N, Qiao C, Ni T, Li Z, Yu B, Guo Q, Wei L.
    Mol Carcinog; 2016 Sep; 55(9):1317-28. PubMed ID: 26258875
    [Abstract] [Full Text] [Related]

  • 2. Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells.
    Tao L, Wei L, Liu Y, Ding Y, Liu X, Zhang X, Wang X, Yao Y, Lu J, Wang Q, Hu R.
    Biochem Pharmacol; 2017 Feb 01; 125():12-25. PubMed ID: 27818240
    [Abstract] [Full Text] [Related]

  • 3. Flavonoid GL-V9 induces apoptosis and inhibits glycolysis of breast cancer via disrupting GSK-3β-modulated mitochondrial binding of HKII.
    Guo Y, Wei L, Zhou Y, Lu N, Tang X, Li Z, Wang X.
    Free Radic Biol Med; 2020 Jan 01; 146():119-129. PubMed ID: 31669347
    [Abstract] [Full Text] [Related]

  • 4. Curcumin inhibits aerobic glycolysis and induces mitochondrial-mediated apoptosis through hexokinase II in human colorectal cancer cells in vitro.
    Wang K, Fan H, Chen Q, Ma G, Zhu M, Zhang X, Zhang Y, Yu J.
    Anticancer Drugs; 2015 Jan 01; 26(1):15-24. PubMed ID: 25229889
    [Abstract] [Full Text] [Related]

  • 5. Cerulenin-induced apoptosis is mediated by disrupting the interaction between AIF and hexokinase II.
    Jeong NY, Yoo YH.
    Int J Oncol; 2012 Jun 01; 40(6):1949-56. PubMed ID: 22426850
    [Abstract] [Full Text] [Related]

  • 6. Glycolysis inhibition and apoptosis induction in human prostate cancer cells by FV-429-mediated regulation of AR-AKT-HK2 signaling network.
    Chen X, Wei L, Yang L, Guo W, Guo Q, Zhou Y.
    Food Chem Toxicol; 2020 Sep 01; 143():111517. PubMed ID: 32619556
    [Abstract] [Full Text] [Related]

  • 7. Caspase-dependent and caspase-independent induction of apoptosis in breast cancer by fucoidan via the PI3K/AKT/GSK3β pathway in vivo and in vitro.
    Xue M, Ji X, Xue C, Liang H, Ge Y, He X, Zhang L, Bian K, Zhang L.
    Biomed Pharmacother; 2017 Oct 01; 94():898-908. PubMed ID: 28810530
    [Abstract] [Full Text] [Related]

  • 8. Astragaloside IV reduces neuronal apoptosis and parthanatos in ischemic injury by preserving mitochondrial hexokinase-II.
    Li Y, Yang Y, Zhao Y, Zhang J, Liu B, Jiao S, Zhang X.
    Free Radic Biol Med; 2019 Feb 01; 131():251-263. PubMed ID: 30502455
    [Abstract] [Full Text] [Related]

  • 9. Gomisin J inhibits the glioma progression by inducing apoptosis and reducing HKII-regulated glycolysis.
    Li R, Yang W.
    Biochem Biophys Res Commun; 2020 Aug 13; 529(1):15-22. PubMed ID: 32560813
    [Abstract] [Full Text] [Related]

  • 10. Reactive oxygen species-mitochondria pathway involved in FV-429-induced apoptosis in human hepatocellular carcinoma HepG2 cells.
    Yang Z, Qiang L, Wu T, Chen FH, Yang HY, Zhao Q, Zou MJ, Sun YJ, Li ZY, Guo QL.
    Anticancer Drugs; 2011 Oct 13; 22(9):886-95. PubMed ID: 21730822
    [Abstract] [Full Text] [Related]

  • 11. Targeting VDAC-bound hexokinase II: a promising approach for concomitant anti-cancer therapy.
    Krasnov GS, Dmitriev AA, Lakunina VA, Kirpiy AA, Kudryavtseva AV.
    Expert Opin Ther Targets; 2013 Oct 13; 17(10):1221-33. PubMed ID: 23984984
    [Abstract] [Full Text] [Related]

  • 12. Akt mediates mitochondrial protection in cardiomyocytes through phosphorylation of mitochondrial hexokinase-II.
    Miyamoto S, Murphy AN, Brown JH.
    Cell Death Differ; 2008 Mar 13; 15(3):521-9. PubMed ID: 18064042
    [Abstract] [Full Text] [Related]

  • 13. [Hirsutine induces apoptosis of human breast cancer MDA-MB-231 cells through mitochondrial pathway].
    Huang QW, Zhai NN, Huang T, Li DM.
    Sheng Li Xue Bao; 2018 Feb 25; 70(1):40-46. PubMed ID: 29492513
    [Abstract] [Full Text] [Related]

  • 14. Wogonin induces apoptosis and down-regulates survivin in human breast cancer MCF-7 cells by modulating PI3K-AKT pathway.
    Huang KF, Zhang GD, Huang YQ, Diao Y.
    Int Immunopharmacol; 2012 Feb 25; 12(2):334-41. PubMed ID: 22182776
    [Abstract] [Full Text] [Related]

  • 15. Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2.
    Xu D, Jin J, Yu H, Zhao Z, Ma D, Zhang C, Jiang H.
    J Exp Clin Cancer Res; 2017 Mar 20; 36(1):44. PubMed ID: 28320429
    [Abstract] [Full Text] [Related]

  • 16. LYG-202 exerts antitumor effect on PI3K/Akt signaling pathway in human breast cancer cells.
    Zhao Y, Wang X, Sun Y, Zhou Y, Yin Y, Ding Y, Li Z, Guo Q, Lu N.
    Apoptosis; 2015 Sep 20; 20(9):1253-69. PubMed ID: 26153346
    [Abstract] [Full Text] [Related]

  • 17. A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity.
    Rashmi KC, Harsha Raj M, Paul M, Girish KS, Salimath BP, Aparna HS.
    Chem Biol Interact; 2019 Feb 01; 299():120-130. PubMed ID: 30543781
    [Abstract] [Full Text] [Related]

  • 18. Fangchinoline inhibits cell proliferation via Akt/GSK-3beta/ cyclin D1 signaling and induces apoptosis in MDA-MB-231 breast cancer cells.
    Wang CD, Yuan CF, Bu YQ, Wu XM, Wan JY, Zhang L, Hu N, Liu XJ, Zu Y, Liu GL, Song FZ.
    Asian Pac J Cancer Prev; 2014 Feb 01; 15(2):769-73. PubMed ID: 24568493
    [Abstract] [Full Text] [Related]

  • 19. Role of mitochondria-associated hexokinase II in cancer cell death induced by 3-bromopyruvate.
    Chen Z, Zhang H, Lu W, Huang P.
    Biochim Biophys Acta; 2009 May 01; 1787(5):553-60. PubMed ID: 19285479
    [Abstract] [Full Text] [Related]

  • 20. Plant cyclopeptide RA-V kills human breast cancer cells by inducing mitochondria-mediated apoptosis through blocking PDK1-AKT interaction.
    Fang XY, Chen W, Fan JT, Song R, Wang L, Gu YH, Zeng GZ, Shen Y, Wu XF, Tan NH, Xu Q, Sun Y.
    Toxicol Appl Pharmacol; 2013 Feb 15; 267(1):95-103. PubMed ID: 23274515
    [Abstract] [Full Text] [Related]

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