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613 related items for PubMed ID: 26259512

  • 1. Matrine derivative WM130 inhibits hepatocellular carcinoma by suppressing EGFR/ERK/MMP-2 and PTEN/AKT signaling pathways.
    Qian L, Liu Y, Xu Y, Ji W, Wu Q, Liu Y, Gao Q, Su C.
    Cancer Lett; 2015 Nov 01; 368(1):126-134. PubMed ID: 26259512
    [Abstract] [Full Text] [Related]

  • 2. WM130 preferentially inhibits hepatic cancer stem-like cells by suppressing AKT/GSK3β/β-catenin signaling pathway.
    Ni CX, Qi Y, Zhang J, Liu Y, Xu WH, Xu J, Hu HG, Wu QY, Wang Y, Zhang JP.
    Oncotarget; 2016 Nov 29; 7(48):79544-79556. PubMed ID: 27783993
    [Abstract] [Full Text] [Related]

  • 3. In vitro and in vivo anti-metastatic effect of the alkaliod matrine from Sophora flavecens on hepatocellular carcinoma and its mechanisms.
    Dai M, Chen N, Li J, Tan L, Li X, Wen J, Lei L, Guo D.
    Phytomedicine; 2021 Jul 29; 87():153580. PubMed ID: 34029939
    [Abstract] [Full Text] [Related]

  • 4. Hydrogen sulfide acts as a double-edged sword in human hepatocellular carcinoma cells through EGFR/ERK/MMP-2 and PTEN/AKT signaling pathways.
    Wu D, Li M, Tian W, Wang S, Cui L, Li H, Wang H, Ji A, Li Y.
    Sci Rep; 2017 Jul 11; 7(1):5134. PubMed ID: 28698660
    [Abstract] [Full Text] [Related]

  • 5. A novel matrine derivate inhibits differentiated human hepatoma cells and hepatic cancer stem-like cells by suppressing PI3K/AKT signaling pathways.
    Liu Y, Qi Y, Bai ZH, Ni CX, Ren QH, Xu WH, Xu J, Hu HG, Qiu L, Li JZ, He ZG, Zhang JP.
    Acta Pharmacol Sin; 2017 Jan 11; 38(1):120-132. PubMed ID: 27773936
    [Abstract] [Full Text] [Related]

  • 6. A Novel Matrine Derivative WM130 Inhibits Activation of Hepatic Stellate Cells and Attenuates Dimethylnitrosamine-Induced Liver Fibrosis in Rats.
    Xu Y, Peng Z, Ji W, Li X, Lin X, Qian L, Li X, Chai X, Wu Q, Gao Q, Su C.
    Biomed Res Int; 2015 Jan 11; 2015():203978. PubMed ID: 26167476
    [Abstract] [Full Text] [Related]

  • 7. MicroRNA-21 suppresses PTEN and hSulf-1 expression and promotes hepatocellular carcinoma progression through AKT/ERK pathways.
    Bao L, Yan Y, Xu C, Ji W, Shen S, Xu G, Zeng Y, Sun B, Qian H, Chen L, Wu M, Su C, Chen J.
    Cancer Lett; 2013 Sep 01; 337(2):226-36. PubMed ID: 23684551
    [Abstract] [Full Text] [Related]

  • 8. Mannose-mediated inhibitory effects of PA-MSHA on invasion and metastasis of hepatocellular carcinoma via EGFR/Akt/IκBβ/NF-κB pathway.
    Li T, Dong ZR, Guo ZY, Wang CH, Zhi XT, Zhou JW, Li DK, Chen ZT, Chen ZQ, Hu SY.
    Liver Int; 2015 Apr 01; 35(4):1416-29. PubMed ID: 25066210
    [Abstract] [Full Text] [Related]

  • 9. MiR-21 mediates sorafenib resistance of hepatocellular carcinoma cells by inhibiting autophagy via the PTEN/Akt pathway.
    He C, Dong X, Zhai B, Jiang X, Dong D, Li B, Jiang H, Xu S, Sun X.
    Oncotarget; 2015 Oct 06; 6(30):28867-81. PubMed ID: 26311740
    [Abstract] [Full Text] [Related]

  • 10. Matrine inhibits invasion and migration of gallbladder cancer via regulating the PI3K/AKT signaling pathway.
    Mo RL, Li Z, Zhang P, Sheng MH, Han GC, Sun DQ.
    Naunyn Schmiedebergs Arch Pharmacol; 2024 Oct 06; 397(10):8129-8143. PubMed ID: 38789637
    [Abstract] [Full Text] [Related]

  • 11. Differentiation therapy of hepatocellular carcinoma by inhibiting the activity of AKT/GSK-3β/β-catenin axis and TGF-β induced EMT with sophocarpine.
    Zhang PP, Wang PQ, Qiao CP, Zhang Q, Zhang JP, Chen F, Zhang X, Xie WF, Yuan ZL, Li ZS, Chen YX.
    Cancer Lett; 2016 Jun 28; 376(1):95-103. PubMed ID: 26945965
    [Abstract] [Full Text] [Related]

  • 12. A novel matrine derivative WM622 inhibits hepatocellular carcinoma by inhibiting PI3K/AKT signaling pathways.
    Sun X, Zhuo XB, Hu YP, Zheng X, Zhao QJ.
    Mol Cell Biochem; 2018 Dec 28; 449(1-2):47-54. PubMed ID: 29532226
    [Abstract] [Full Text] [Related]

  • 13. PTEN inhibits the migration and invasion of HepG2 cells by coordinately decreasing MMP expression via the PI3K/Akt pathway.
    Tian T, Nan KJ, Guo H, Wang WJ, Ruan ZP, Wang SH, Liang X, Lu CX.
    Oncol Rep; 2010 Jun 28; 23(6):1593-600. PubMed ID: 20428814
    [Abstract] [Full Text] [Related]

  • 14. Matrine suppresses invasion of castration-resistant prostate cancer cells by downregulating MMP-2/9 via NF-κB signaling pathway.
    Huang H, Du T, Xu G, Lai Y, Fan X, Chen X, Li W, Yue F, Li Q, Liu L, Li K.
    Int J Oncol; 2017 Feb 28; 50(2):640-648. PubMed ID: 28000853
    [Abstract] [Full Text] [Related]

  • 15. Hydrazinocurcumin and 5-fluorouracil enhance apoptosis and restrain tumorigenicity of HepG2 cells via disrupting the PTEN-mediated PI3K/Akt signaling pathway.
    Zhou Y, Zhang M, Zhang Z, Jia Y, Zhang C, Peng L.
    Biomed Pharmacother; 2020 Sep 28; 129():109851. PubMed ID: 32559627
    [Abstract] [Full Text] [Related]

  • 16. MiR-3663-3p participates in the anti-hepatocellular carcinoma proliferation activity of baicalein by targeting SH3GL1 and negatively regulating EGFR/ERK/NF-κB signaling.
    Tian J, Li J, Bie B, Sun J, Mu Y, Shi M, Zhang S, Kong G, Li Z, Guo Y.
    Toxicol Appl Pharmacol; 2021 Jun 01; 420():115522. PubMed ID: 33838155
    [Abstract] [Full Text] [Related]

  • 17. Baohuoside-1 targeting mTOR inducing apoptsis to inhibit hepatocellular carcinoma proliferation, invasion and migration.
    Guo Y, Zhu H, Weng M, Chen B, Wang C, Sun L.
    Biomed Pharmacother; 2020 Aug 01; 128():110366. PubMed ID: 32526459
    [Abstract] [Full Text] [Related]

  • 18. Alpha1-ACT Functions as a Tumour Suppressor in Hepatocellular Carcinoma by Inhibiting the PI3K/AKT/mTOR Signalling Pathway via Activation of PTEN.
    Zhu H, Liu Q, Tang J, Xie Y, Xu X, Huang R, Zhang Y, Jin K, Sun B.
    Cell Physiol Biochem; 2017 Aug 01; 41(6):2289-2306. PubMed ID: 28456796
    [Abstract] [Full Text] [Related]

  • 19. Scutellarin inhibits human renal cancer cell proliferation and migration via upregulation of PTEN.
    Deng W, Han W, Fan T, Wang X, Cheng Z, Wan B, Chen J.
    Biomed Pharmacother; 2018 Nov 01; 107():1505-1513. PubMed ID: 30257368
    [Abstract] [Full Text] [Related]

  • 20. TQ inhibits hepatocellular carcinoma growth in vitro and in vivo via repression of Notch signaling.
    Ke X, Zhao Y, Lu X, Wang Z, Liu Y, Ren M, Lu G, Zhang D, Sun Z, Xu Z, Song JH, Cheng Y, Meltzer SJ, He S.
    Oncotarget; 2015 Oct 20; 6(32):32610-21. PubMed ID: 26416455
    [Abstract] [Full Text] [Related]

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