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696 related items for PubMed ID: 26271598

  • 1. Combined anti CXC receptors 1 and 2 therapy is a promising anti-inflammatory treatment for respiratory diseases by reducing neutrophil migration and activation.
    Planagumà A, Domènech T, Pont M, Calama E, García-González V, López R, Aulí M, López M, Fonquerna S, Ramos I, de Alba J, Nueda A, Prats N, Segarra V, Miralpeix M, Lehner MD.
    Pulm Pharmacol Ther; 2015 Oct; 34():37-45. PubMed ID: 26271598
    [Abstract] [Full Text] [Related]

  • 2. Pharmacological characterization of Sch527123, a potent allosteric CXCR1/CXCR2 antagonist.
    Gonsiorek W, Fan X, Hesk D, Fossetta J, Qiu H, Jakway J, Billah M, Dwyer M, Chao J, Deno G, Taveras A, Lundell DJ, Hipkin RW.
    J Pharmacol Exp Ther; 2007 Aug; 322(2):477-85. PubMed ID: 17496166
    [Abstract] [Full Text] [Related]

  • 3. LPS challenge in healthy subjects: an investigation of neutrophil chemotaxis mechanisms involving CXCR1 and CXCR2.
    Aul R, Patel S, Summerhill S, Kilty I, Plumb J, Singh D.
    Int Immunopharmacol; 2012 Jul; 13(3):225-31. PubMed ID: 22561413
    [Abstract] [Full Text] [Related]

  • 4. A novel, orally active CXCR1/2 receptor antagonist, Sch527123, inhibits neutrophil recruitment, mucus production, and goblet cell hyperplasia in animal models of pulmonary inflammation.
    Chapman RW, Minnicozzi M, Celly CS, Phillips JE, Kung TT, Hipkin RW, Fan X, Rindgen D, Deno G, Bond R, Gonsiorek W, Billah MM, Fine JS, Hey JA.
    J Pharmacol Exp Ther; 2007 Aug; 322(2):486-93. PubMed ID: 17496165
    [Abstract] [Full Text] [Related]

  • 5. Neutrophil chemotaxis caused by chronic obstructive pulmonary disease alveolar macrophages: the role of CXCL8 and the receptors CXCR1/CXCR2.
    Kaur M, Singh D.
    J Pharmacol Exp Ther; 2013 Oct; 347(1):173-80. PubMed ID: 23912333
    [Abstract] [Full Text] [Related]

  • 6. The combined CXCR1/CXCR2 antagonist CXCL8(3-74)K11R/G31P blocks neutrophil infiltration, pyrexia, and pulmonary vascular pathology in endotoxemic animals.
    Gordon JR, Li F, Zhang X, Wang W, Zhao X, Nayyar A.
    J Leukoc Biol; 2005 Dec; 78(6):1265-72. PubMed ID: 16204619
    [Abstract] [Full Text] [Related]

  • 7. The effects of a CXCR1/CXCR2 antagonist on neutrophil migration in mild atopic asthmatic subjects.
    Todd CM, Salter BM, Murphy DM, Watson RM, Howie KJ, Milot J, Sadeh J, Boulet LP, O'Byrne PM, Gauvreau GM.
    Pulm Pharmacol Ther; 2016 Dec; 41():34-39. PubMed ID: 27640067
    [Abstract] [Full Text] [Related]

  • 8. Humanized forms of the CXCR1/CXCR2 antagonist, bovine CXCL8((3-74))K11R/G31P, effectively block ELR-CXC chemokine activity and airway endotoxemia pathology.
    Zhao X, Li F, Town JR, Zhang X, Wang W, Gordon JR.
    Int Immunopharmacol; 2007 Dec 15; 7(13):1723-31. PubMed ID: 17996682
    [Abstract] [Full Text] [Related]

  • 9. The CXCL8/IL-8 chemokine family and its receptors in inflammatory diseases.
    Russo RC, Garcia CC, Teixeira MM, Amaral FA.
    Expert Rev Clin Immunol; 2014 May 15; 10(5):593-619. PubMed ID: 24678812
    [Abstract] [Full Text] [Related]

  • 10. Elucidation of Distinct Roles of Guinea Pig CXCR1 and CXCR2 in Neutrophil Migration toward IL-8 and GROα by Specific Antibodies.
    Tanaka K, Yoshitomi T, Hirahara K.
    Biol Pharm Bull; 2017 May 15; 40(5):729-732. PubMed ID: 28458362
    [Abstract] [Full Text] [Related]

  • 11. Rabbit neutrophil chemotactic protein (NCP) activates both CXCR1 and CXCR2 and is the functional homologue for human CXCL6.
    Catusse J, Struyf S, Wuyts A, Weyler M, Loos T, Gijsbers K, Gouwy M, Proost P, Van Damme J.
    Biochem Pharmacol; 2004 Nov 15; 68(10):1947-55. PubMed ID: 15476666
    [Abstract] [Full Text] [Related]

  • 12. ELR-CXC chemokine receptor antagonism targets inflammatory responses at multiple levels.
    Zhao X, Town JR, Li F, Zhang X, Cockcroft DW, Gordon JR.
    J Immunol; 2009 Mar 01; 182(5):3213-22. PubMed ID: 19234219
    [Abstract] [Full Text] [Related]

  • 13. CXCR2 antagonists block the N-Ac-PGP-induced neutrophil influx in the airways of mice, but not the production of the chemokine CXCL1.
    Braber S, Overbeek SA, Koelink PJ, Henricks PA, Zaman GJ, Garssen J, Kraneveld AD, Folkerts G.
    Eur J Pharmacol; 2011 Oct 15; 668(3):443-9. PubMed ID: 21458445
    [Abstract] [Full Text] [Related]

  • 14. Porcine CXCR1/2 antagonist CXCL8(3-72)G31P inhibits lung inflammation in LPS-challenged mice.
    Wang X, Li Y, Li L, Jiao Z, Liu X, Cheng G, Gu C, Hu X, Zhang W.
    Sci Rep; 2020 Jan 27; 10(1):1210. PubMed ID: 31988368
    [Abstract] [Full Text] [Related]

  • 15. Development of a systemically-active dual CXCR1/CXCR2 allosteric inhibitor and its efficacy in a model of transient cerebral ischemia in the rat.
    Garau A, Bertini R, Mosca M, Bizzarri C, Anacardio R, Triulzi S, Allegretti M, Ghezzi P, Villa P.
    Eur Cytokine Netw; 2006 Mar 27; 17(1):35-41. PubMed ID: 16613761
    [Abstract] [Full Text] [Related]

  • 16. Cloning and characterization of guinea pig CXCR1.
    Takahashi M, Jeevan A, Sawant K, McMurray DN, Yoshimura T.
    Mol Immunol; 2007 Feb 27; 44(5):878-88. PubMed ID: 16712933
    [Abstract] [Full Text] [Related]

  • 17. Pharmacological characterization of AZD5069, a slowly reversible CXC chemokine receptor 2 antagonist.
    Nicholls DJ, Wiley K, Dainty I, MacIntosh F, Phillips C, Gaw A, Mårdh CK.
    J Pharmacol Exp Ther; 2015 May 27; 353(2):340-50. PubMed ID: 25736418
    [Abstract] [Full Text] [Related]

  • 18. SCH527123, a novel CXCR2 antagonist, inhibits ozone-induced neutrophilia in healthy subjects.
    Holz O, Khalilieh S, Ludwig-Sengpiel A, Watz H, Stryszak P, Soni P, Tsai M, Sadeh J, Magnussen H.
    Eur Respir J; 2010 Mar 27; 35(3):564-70. PubMed ID: 19643947
    [Abstract] [Full Text] [Related]

  • 19. Effect of formoterol and budesonide on chemokine release, chemokine receptor expression and chemotaxis in human neutrophils.
    Strandberg K, Blidberg K, Sahlander K, Palmberg L, Larsson K.
    Pulm Pharmacol Ther; 2010 Aug 27; 23(4):316-23. PubMed ID: 20307681
    [Abstract] [Full Text] [Related]

  • 20. Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain.
    Carreira EU, Carregaro V, Teixeira MM, Moriconi A, Aramini A, Verri WA, Ferreira SH, Cunha FQ, Cunha TM.
    Eur J Pain; 2013 May 27; 17(5):654-63. PubMed ID: 23132735
    [Abstract] [Full Text] [Related]

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