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Journal Abstract Search

177 related items for PubMed ID: 26276581

  • 1. A New Rapid In Vitro Assay for Assessing Reactivity of Acyl Glucuronides.
    Zhong S, Jones R, Lu W, Schadt S, Ottaviani G.
    Drug Metab Dispos; 2015 Nov; 43(11):1711-7. PubMed ID: 26276581
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  • 2. Significantly Different Covalent Binding of Oxidative Metabolites, Acyl Glucuronides, and S-Acyl CoA Conjugates Formed from Xenobiotic Carboxylic Acids in Human Liver Microsomes.
    Darnell M, Breitholtz K, Isin EM, Jurva U, Weidolf L.
    Chem Res Toxicol; 2015 May 18; 28(5):886-96. PubMed ID: 25803559
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  • 3. Acyl glucuronide metabolites: Implications for drug safety assessment.
    Van Vleet TR, Liu H, Lee A, Blomme EAG.
    Toxicol Lett; 2017 Apr 15; 272():1-7. PubMed ID: 28286018
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  • 7. Acyl glucuronides: the good, the bad and the ugly.
    Regan SL, Maggs JL, Hammond TG, Lambert C, Williams DP, Park BK.
    Biopharm Drug Dispos; 2010 Oct 15; 31(7):367-95. PubMed ID: 20830700
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  • 8. Safety Assessment of Acyl Glucuronides-A Simplified Paradigm.
    Smith DA, Hammond T, Baillie TA.
    Drug Metab Dispos; 2018 Jun 15; 46(6):908-912. PubMed ID: 29559442
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  • 9. Acyl glucuronide reactivity in perspective: biological consequences.
    Bailey MJ, Dickinson RG.
    Chem Biol Interact; 2003 May 06; 145(2):117-37. PubMed ID: 12686489
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  • 10. New Perspectives on Acyl Glucuronide Risk Assessment in Drug Discovery: Investigation of In vitro Stability, In situ Reactivity, and Bioactivation.
    Gunduz M, Argikar UA, Cirello AL, Dumouchel JL.
    Drug Metab Lett; 2018 May 06; 12(2):84-92. PubMed ID: 29886840
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  • 11. Determination of degradation pathways and kinetics of acyl glucuronides by NMR spectroscopy.
    Walker GS, Atherton J, Bauman J, Kohl C, Lam W, Reily M, Lou Z, Mutlib A.
    Chem Res Toxicol; 2007 Jun 06; 20(6):876-86. PubMed ID: 17536843
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  • 12. Xenobiotic acyl glucuronides and acyl CoA thioesters as protein-reactive metabolites with the potential to cause idiosyncratic drug reactions.
    Boelsterli UA.
    Curr Drug Metab; 2002 Aug 06; 3(4):439-50. PubMed ID: 12093359
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  • 14. The influence of physicochemical properties on the reactivity and stability of acyl glucuronides †.
    Camilleri P, Buch A, Soldo B, Hutt AJ.
    Xenobiotica; 2018 Sep 06; 48(9):958-972. PubMed ID: 28967291
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  • 16. Studies on the chemical reactivity of 2-phenylpropionic acid 1-O-acyl glucuronide and S-acyl-CoA thioester metabolites.
    Li C, Benet LZ, Grillo MP.
    Chem Res Toxicol; 2002 Oct 06; 15(10):1309-17. PubMed ID: 12387630
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  • 18. 18O-Enabled High-Throughput Acyl Glucuronide Stability Assay.
    Yu ZJ, Le H, Tang J, Yue Q, Zhang J, Murray B, Liu X, Smith BJ, Subramanian R.
    Chem Res Toxicol; 2022 Aug 15; 35(8):1400-1409. PubMed ID: 35833852
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  • 19. Structural characterization of anti-HIV drug candidate PA-457 [3-O-(3',3'-dimethylsuccinyl)-betulinic acid] and its acyl glucuronides in rat bile and evaluation of in vitro stability in human and animal liver microsomes and plasma.
    Wen Z, Stern ST, Martin DE, Lee KH, Smith PC.
    Drug Metab Dispos; 2006 Sep 15; 34(9):1436-42. PubMed ID: 16751262
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