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333 related items for PubMed ID: 26286618

  • 1. Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia.
    Schumacher FR, Siew K, Zhang J, Johnson C, Wood N, Cleary SE, Al Maskari RS, Ferryman JT, Hardege I, Yasmin, Figg NL, Enchev R, Knebel A, O'Shaughnessy KM, Kurz T.
    EMBO Mol Med; 2015 Oct; 7(10):1285-306. PubMed ID: 26286618
    [Abstract] [Full Text] [Related]

  • 2. ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403-459 mutation.
    Murthy M, Kurz T, O'Shaughnessy KM.
    Physiol Rep; 2016 Jul; 4(13):. PubMed ID: 27378813
    [Abstract] [Full Text] [Related]

  • 3. Hyperkalemic hypertension-associated cullin 3 promotes WNK signaling by degrading KLHL3.
    McCormick JA, Yang CL, Zhang C, Davidge B, Blankenstein KI, Terker AS, Yarbrough B, Meermeier NP, Park HJ, McCully B, West M, Borschewski A, Himmerkus N, Bleich M, Bachmann S, Mutig K, Argaiz ER, Gamba G, Singer JD, Ellison DH.
    J Clin Invest; 2014 Nov; 124(11):4723-36. PubMed ID: 25250572
    [Abstract] [Full Text] [Related]

  • 4. The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.
    Ohta A, Schumacher FR, Mehellou Y, Johnson C, Knebel A, Macartney TJ, Wood NT, Alessi DR, Kurz T.
    Biochem J; 2013 Apr 01; 451(1):111-22. PubMed ID: 23387299
    [Abstract] [Full Text] [Related]

  • 5. Renal COP9 Signalosome Deficiency Alters CUL3-KLHL3-WNK Signaling Pathway.
    Cornelius RJ, Si J, Cuevas CA, Nelson JW, Gratreak BDK, Pardi R, Yang CL, Ellison DH.
    J Am Soc Nephrol; 2018 Nov 01; 29(11):2627-2640. PubMed ID: 30301860
    [Abstract] [Full Text] [Related]

  • 6. Degradation by Cullin 3 and effect on WNK kinases suggest a role of KLHL2 in the pathogenesis of Familial Hyperkalemic Hypertension.
    Zhang C, Meermeier NP, Terker AS, Blankenstein KI, Singer JD, Hadchouel J, Ellison DH, Yang CL.
    Biochem Biophys Res Commun; 2016 Jan 01; 469(1):44-48. PubMed ID: 26607111
    [Abstract] [Full Text] [Related]

  • 7. Distal convoluted tubule-specific disruption of the COP9 signalosome but not its regulatory target cullin 3 causes tubular injury.
    Maeoka Y, Bradford T, Su XT, Sharma A, Yang CL, Ellison DH, McCormick JA, Cornelius RJ.
    Am J Physiol Renal Physiol; 2024 Oct 01; 327(4):F667-F682. PubMed ID: 39205661
    [Abstract] [Full Text] [Related]

  • 8. Mechanisms and controversies in mutant Cul3-mediated familial hyperkalemic hypertension.
    Ferdaus MZ, McCormick JA.
    Am J Physiol Renal Physiol; 2018 May 01; 314(5):F915-F920. PubMed ID: 29361671
    [Abstract] [Full Text] [Related]

  • 9. Combined Kelch-like 3 and Cullin 3 Degradation is a Central Mechanism in Familial Hyperkalemic Hypertension in Mice.
    Maeoka Y, Ferdaus MZ, Cornelius RJ, Sharma A, Su XT, Miller LN, Robertson JA, Gurley SB, Yang CL, Ellison DH, McCormick JA.
    J Am Soc Nephrol; 2022 Mar 01; 33(3):584-600. PubMed ID: 35064051
    [Abstract] [Full Text] [Related]

  • 10. Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension.
    Cornelius RJ, Zhang C, Erspamer KJ, Agbor LN, Sigmund CD, Singer JD, Yang CL, Ellison DH.
    Am J Physiol Renal Physiol; 2018 Oct 01; 315(4):F1006-F1018. PubMed ID: 29897280
    [Abstract] [Full Text] [Related]

  • 11. Cullin 3 mutant causing familial hyperkalemic hypertension lacks normal activity in the kidney.
    Maeoka Y, Cornelius RJ, Ferdaus MZ, Sharma A, Nguyen LT, McCormick JA.
    Am J Physiol Renal Physiol; 2022 Nov 01; 323(5):F564-F576. PubMed ID: 36007890
    [Abstract] [Full Text] [Related]

  • 12. Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects.
    Ferdaus MZ, Miller LN, Agbor LN, Saritas T, Singer JD, Sigmund CD, McCormick JA.
    JCI Insight; 2017 Dec 21; 2(24):. PubMed ID: 29263298
    [Abstract] [Full Text] [Related]

  • 13. Decreased KLHL3 expression is involved in the pathogenesis of pseudohypoaldosteronism type II caused by cullin 3 mutation in vivo.
    Yoshida S, Araki Y, Mori T, Sasaki E, Kasagi Y, Isobe K, Susa K, Inoue Y, Bomont P, Okado T, Rai T, Uchida S, Sohara E.
    Clin Exp Nephrol; 2018 Dec 21; 22(6):1251-1257. PubMed ID: 29869755
    [Abstract] [Full Text] [Related]

  • 14. Novel CUL3 Variant Causing Familial Hyperkalemic Hypertension Impairs Regulation and Function of Ubiquitin Ligase Activity.
    Chatrathi HE, Collins JC, Wolfe LA, Markello TC, Adams DR, Gahl WA, Werner A, Sharma P.
    Hypertension; 2022 Jan 21; 79(1):60-75. PubMed ID: 34878901
    [Abstract] [Full Text] [Related]

  • 15. Hypertension-causing cullin 3 mutations disrupt COP9 signalosome binding.
    Cornelius RJ, Yang CL, Ellison DH.
    Am J Physiol Renal Physiol; 2020 Jan 01; 318(1):F204-F208. PubMed ID: 31813255
    [Abstract] [Full Text] [Related]

  • 16. Mutations in kelch-like 3 and cullin 3 cause hypertension and electrolyte abnormalities.
    Boyden LM, Choi M, Choate KA, Nelson-Williams CJ, Farhi A, Toka HR, Tikhonova IR, Bjornson R, Mane SM, Colussi G, Lebel M, Gordon RD, Semmekrot BA, Poujol A, Välimäki MJ, De Ferrari ME, Sanjad SA, Gutkin M, Karet FE, Tucci JR, Stockigt JR, Keppler-Noreuil KM, Porter CC, Anand SK, Whiteford ML, Davis ID, Dewar SB, Bettinelli A, Fadrowski JJ, Belsha CW, Hunley TE, Nelson RD, Trachtman H, Cole TR, Pinsk M, Bockenhauer D, Shenoy M, Vaidyanathan P, Foreman JW, Rasoulpour M, Thameem F, Al-Shahrouri HZ, Radhakrishnan J, Gharavi AG, Goilav B, Lifton RP.
    Nature; 2012 Jan 22; 482(7383):98-102. PubMed ID: 22266938
    [Abstract] [Full Text] [Related]

  • 17. Kelch-like 3/Cullin 3 ubiquitin ligase complex and WNK signaling in salt-sensitive hypertension and electrolyte disorder.
    Sohara E, Uchida S.
    Nephrol Dial Transplant; 2016 Sep 22; 31(9):1417-24. PubMed ID: 26152401
    [Abstract] [Full Text] [Related]

  • 18. Cullin 3 Exon 9 Deletion in Familial Hyperkalemic Hypertension Impairs Cullin3-Ring-E3 Ligase (CRL3) Dynamic Regulation and Cycling.
    Kouranti I, Abdel Khalek W, Mazurkiewicz S, Loisel-Ferreira I, Gautreau AM, Pintard L, Jeunemaitre X, Clauser E.
    Int J Mol Sci; 2022 May 05; 23(9):. PubMed ID: 35563538
    [Abstract] [Full Text] [Related]

  • 19. Detection of mutations in KLHL3 and CUL3 in families with FHHt (familial hyperkalaemic hypertension or Gordon's syndrome).
    Glover M, Ware JS, Henry A, Wolley M, Walsh R, Wain LV, Xu S, Van't Hoff WG, Tobin MD, Hall IP, Cook S, Gordon RD, Stowasser M, O'Shaughnessy KM.
    Clin Sci (Lond); 2014 May 05; 126(10):721-6. PubMed ID: 24266877
    [Abstract] [Full Text] [Related]

  • 20. Generation and analysis of a mouse model of pseudohypoaldosteronism type II caused by KLHL3 mutation in BTB domain.
    Lin CM, Cheng CJ, Yang SS, Tseng MH, Yen MT, Sung CC, Lin SH.
    FASEB J; 2019 Jan 05; 33(1):1051-1061. PubMed ID: 30148674
    [Abstract] [Full Text] [Related]

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