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Journal Abstract Search


506 related items for PubMed ID: 26297434

  • 1. Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner.
    Kiprianova I, Remy J, Milosch N, Mohrenz IV, Seifert V, Aigner A, Kögel D.
    Neoplasia; 2015 Jul; 17(7):564-73. PubMed ID: 26297434
    [Abstract] [Full Text] [Related]

  • 2. Sorafenib potentiates ABT-737-induced apoptosis in human oral cancer cells.
    Kim LH, Shin JA, Jang B, Yang IH, Won DH, Jeong JH, Chung TH, Cho NP, Cho SD.
    Arch Oral Biol; 2017 Jan; 73():1-6. PubMed ID: 27632413
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  • 3. Inhibition of PIM1 blocks the autophagic flux to sensitize glioblastoma cells to ABT-737-induced apoptosis.
    Remy J, Linder B, Weirauch U, Konovalova J, Marschalek R, Aigner A, Kögel D.
    Biochim Biophys Acta Mol Cell Res; 2019 Feb; 1866(2):175-189. PubMed ID: 30389373
    [Abstract] [Full Text] [Related]

  • 4. 'Seed' analysis of off-target siRNAs reveals an essential role of Mcl-1 in resistance to the small-molecule Bcl-2/Bcl-XL inhibitor ABT-737.
    Lin X, Morgan-Lappe S, Huang X, Li L, Zakula DM, Vernetti LA, Fesik SW, Shen Y.
    Oncogene; 2007 Jun 07; 26(27):3972-9. PubMed ID: 17173063
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  • 5. Ionizing radiation sensitizes breast cancer cells to Bcl-2 inhibitor, ABT-737, through regulating Mcl-1.
    Wu H, Schiff DS, Lin Y, Neboori HJ, Goyal S, Feng Z, Haffty BG.
    Radiat Res; 2014 Dec 07; 182(6):618-25. PubMed ID: 25409124
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  • 6. The Bcl-xL inhibitor, ABT-737, efficiently induces apoptosis and suppresses growth of hepatoma cells in combination with sorafenib.
    Hikita H, Takehara T, Shimizu S, Kodama T, Shigekawa M, Iwase K, Hosui A, Miyagi T, Tatsumi T, Ishida H, Li W, Kanto T, Hiramatsu N, Hayashi N.
    Hepatology; 2010 Oct 07; 52(4):1310-21. PubMed ID: 20799354
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  • 8. BMX acts downstream of PI3K to promote colorectal cancer cell survival and pathway inhibition sensitizes to the BH3 mimetic ABT-737.
    Potter DS, Kelly P, Denneny O, Juvin V, Stephens LR, Dive C, Morrow CJ.
    Neoplasia; 2014 Feb 07; 16(2):147-57. PubMed ID: 24709422
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  • 10. BH3 mimetic ABT-737 and a proteasome inhibitor synergistically kill melanomas through Noxa-dependent apoptosis.
    Miller LA, Goldstein NB, Johannes WU, Walton CH, Fujita M, Norris DA, Shellman YG.
    J Invest Dermatol; 2009 Apr 07; 129(4):964-71. PubMed ID: 18987671
    [Abstract] [Full Text] [Related]

  • 11. Co-administration of ABT-737 and SAHA induces apoptosis, mediated by Noxa upregulation, Bax activation and mitochondrial dysfunction in PTEN-intact malignant human glioma cell lines.
    Foster KA, Jane EP, Premkumar DR, Morales A, Pollack IF.
    J Neurooncol; 2014 Dec 07; 120(3):459-72. PubMed ID: 25139025
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  • 14. Inhibition of p38 MAPK enhances ABT-737-induced cell death in melanoma cell lines: novel regulation of PUMA.
    Keuling AM, Andrew SE, Tron VA.
    Pigment Cell Melanoma Res; 2010 Jun 07; 23(3):430-40. PubMed ID: 20337986
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  • 15. SCF(FBW7) regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction.
    Inuzuka H, Shaik S, Onoyama I, Gao D, Tseng A, Maser RS, Zhai B, Wan L, Gutierrez A, Lau AW, Xiao Y, Christie AL, Aster J, Settleman J, Gygi SP, Kung AL, Look T, Nakayama KI, DePinho RA, Wei W.
    Nature; 2011 Mar 03; 471(7336):104-9. PubMed ID: 21368833
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  • 16. γ-Secretase inhibition promotes cell death, Noxa upregulation, and sensitization to BH3 mimetic ABT-737 in human breast cancer cells.
    Séveno C, Loussouarn D, Bréchet S, Campone M, Juin P, Barillé-Nion S.
    Breast Cancer Res; 2012 Jun 15; 14(3):R96. PubMed ID: 22703841
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  • 19. Inhibition of MARCH5 ubiquitin ligase abrogates MCL1-dependent resistance to BH3 mimetics via NOXA.
    Subramanian A, Andronache A, Li YC, Wade M.
    Oncotarget; 2016 Mar 29; 7(13):15986-6002. PubMed ID: 26910119
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  • 20. Modulation of NOXA and MCL-1 as a strategy for sensitizing melanoma cells to the BH3-mimetic ABT-737.
    Lucas KM, Mohana-Kumaran N, Lau D, Zhang XD, Hersey P, Huang DC, Weninger W, Haass NK, Allen JD.
    Clin Cancer Res; 2012 Feb 01; 18(3):783-95. PubMed ID: 22173547
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