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537 related items for PubMed ID: 26315784

  • 1. Systemic treatment with a 5HT1a agonist induces anti-oxidant protection and preserves the retina from mitochondrial oxidative stress.
    Biswal MR, Ahmed CM, Ildefonso CJ, Han P, Li H, Jivanji H, Mao H, Lewin AS.
    Exp Eye Res; 2015 Nov; 140():94-105. PubMed ID: 26315784
    [Abstract] [Full Text] [Related]

  • 2. Repurposing an orally available drug for the treatment of geographic atrophy.
    Ahmed CM, Biswal MR, Li H, Han P, Ildefonso CJ, Lewin AS.
    Mol Vis; 2016 Nov; 22():294-310. PubMed ID: 27110092
    [Abstract] [Full Text] [Related]

  • 3. The 5HT1a receptor agonist 8-Oh DPAT induces protection from lipofuscin accumulation and oxidative stress in the retinal pigment epithelium.
    Thampi P, Rao HV, Mitter SK, Cai J, Mao H, Li H, Seo S, Qi X, Lewin AS, Romano C, Boulton ME.
    PLoS One; 2012 Nov; 7(4):e34468. PubMed ID: 22509307
    [Abstract] [Full Text] [Related]

  • 4. Mitochondrial oxidative stress in the retinal pigment epithelium leads to localized retinal degeneration.
    Mao H, Seo SJ, Biswal MR, Li H, Conners M, Nandyala A, Jones K, Le YZ, Lewin AS.
    Invest Ophthalmol Vis Sci; 2014 Jul 01; 55(7):4613-27. PubMed ID: 24985474
    [Abstract] [Full Text] [Related]

  • 5. Daily zeaxanthin supplementation prevents atrophy of the retinal pigment epithelium (RPE) in a mouse model of mitochondrial oxidative stress.
    Biswal MR, Justis BD, Han P, Li H, Gierhart D, Dorey CK, Lewin AS.
    PLoS One; 2018 Jul 01; 13(9):e0203816. PubMed ID: 30265681
    [Abstract] [Full Text] [Related]

  • 6. Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors.
    Brown EE, DeWeerd AJ, Ildefonso CJ, Lewin AS, Ash JD.
    Redox Biol; 2019 Jun 01; 24():101201. PubMed ID: 31039480
    [Abstract] [Full Text] [Related]

  • 7. Conditional Induction of Oxidative Stress in RPE: A Mouse Model of Progressive Retinal Degeneration.
    Biswal MR, Ildefonso CJ, Mao H, Seo SJ, Wang Z, Li H, Le YZ, Lewin AS.
    Adv Exp Med Biol; 2016 Jun 01; 854():31-7. PubMed ID: 26427390
    [Abstract] [Full Text] [Related]

  • 8. Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD.
    Mitter SK, Song C, Qi X, Mao H, Rao H, Akin D, Lewin A, Grant M, Dunn W, Ding J, Bowes Rickman C, Boulton M.
    Autophagy; 2014 Jun 01; 10(11):1989-2005. PubMed ID: 25484094
    [Abstract] [Full Text] [Related]

  • 9. SOD2 protects against oxidation-induced apoptosis in mouse retinal pigment epithelium: implications for age-related macular degeneration.
    Kasahara E, Lin LR, Ho YS, Reddy VN.
    Invest Ophthalmol Vis Sci; 2005 Sep 01; 46(9):3426-34. PubMed ID: 16123448
    [Abstract] [Full Text] [Related]

  • 10. Timing of Antioxidant Gene Therapy: Implications for Treating Dry AMD.
    Biswal MR, Han P, Zhu P, Wang Z, Li H, Ildefonso CJ, Lewin AS.
    Invest Ophthalmol Vis Sci; 2017 Feb 01; 58(2):1237-1245. PubMed ID: 28241311
    [Abstract] [Full Text] [Related]

  • 11. Pathological consequences of long-term mitochondrial oxidative stress in the mouse retinal pigment epithelium.
    Seo SJ, Krebs MP, Mao H, Jones K, Conners M, Lewin AS.
    Exp Eye Res; 2012 Aug 01; 101():60-71. PubMed ID: 22687918
    [Abstract] [Full Text] [Related]

  • 12. Inducible RPE-specific GPX4 knockout causes oxidative stress and retinal degeneration with features of age-related macular degeneration.
    Wojciechowski AM, Bell BA, Song Y, Anderson BD, Conomikes A, Petruconis C, Dunaief JL.
    Exp Eye Res; 2024 Oct 01; 247():110028. PubMed ID: 39128667
    [Abstract] [Full Text] [Related]

  • 13. SOD2 knockdown mouse model of early AMD.
    Justilien V, Pang JJ, Renganathan K, Zhan X, Crabb JW, Kim SR, Sparrow JR, Hauswirth WW, Lewin AS.
    Invest Ophthalmol Vis Sci; 2007 Oct 01; 48(10):4407-20. PubMed ID: 17898259
    [Abstract] [Full Text] [Related]

  • 14. Increased susceptibility to fundus camera-delivered light-induced retinal degeneration in mice deficient in oxidative stress response proteins.
    Ding Y, Aredo B, Zhong X, Zhao CX, Ufret-Vincenty RL.
    Exp Eye Res; 2017 Jun 01; 159():58-68. PubMed ID: 28336262
    [Abstract] [Full Text] [Related]

  • 15. Oxidative stress damage circumscribed to the central temporal retinal pigment epithelium in early experimental non-exudative age-related macular degeneration.
    Dieguez HH, Romeo HE, Alaimo A, González Fleitas MF, Aranda ML, Rosenstein RE, Dorfman D.
    Free Radic Biol Med; 2019 Feb 01; 131():72-80. PubMed ID: 30502459
    [Abstract] [Full Text] [Related]

  • 16. The oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice.
    Song D, Zhao L, Li Y, Hadziahmetovic M, Song Y, Connelly J, Spino M, Dunaief JL.
    Invest Ophthalmol Vis Sci; 2014 Jun 26; 55(7):4525-32. PubMed ID: 24970260
    [Abstract] [Full Text] [Related]

  • 17. Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium.
    Yao J, Jia L, Khan N, Lin C, Mitter SK, Boulton ME, Dunaief JL, Klionsky DJ, Guan JL, Thompson DA, Zacks DN.
    Autophagy; 2015 Jun 26; 11(6):939-53. PubMed ID: 26075877
    [Abstract] [Full Text] [Related]

  • 18. Systematic Injection of Low-Dose LPS Transiently Improves the Retina Function and Structure of a Mouse Model of Geographic Atrophy.
    Young BM, Ildefonso CJ.
    Adv Exp Med Biol; 2019 Jun 26; 1185():57-62. PubMed ID: 31884589
    [Abstract] [Full Text] [Related]

  • 19. Mice With a Combined Deficiency of Superoxide Dismutase 1 (Sod1), DJ-1 (Park7), and Parkin (Prkn) Develop Spontaneous Retinal Degeneration With Aging.
    Zhu Y, Aredo B, Chen B, Zhao CX, He YG, Ufret-Vincenty RL.
    Invest Ophthalmol Vis Sci; 2019 Sep 03; 60(12):3740-3751. PubMed ID: 31487745
    [Abstract] [Full Text] [Related]

  • 20. Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration.
    Felszeghy S, Viiri J, Paterno JJ, Hyttinen JMT, Koskela A, Chen M, Leinonen H, Tanila H, Kivinen N, Koistinen A, Toropainen E, Amadio M, Smedowski A, Reinisalo M, Winiarczyk M, Mackiewicz J, Mutikainen M, Ruotsalainen AK, Kettunen M, Jokivarsi K, Sinha D, Kinnunen K, Petrovski G, Blasiak J, Bjørkøy G, Koskelainen A, Skottman H, Urtti A, Salminen A, Kannan R, Ferrington DA, Xu H, Levonen AL, Tavi P, Kauppinen A, Kaarniranta K.
    Redox Biol; 2019 Jan 03; 20():1-12. PubMed ID: 30253279
    [Abstract] [Full Text] [Related]

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