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152 related items for PubMed ID: 26325176
1. Glioblastoma invasion and cooption depend on IRE1α endoribonuclease activity. Jabouille A, Delugin M, Pineau R, Dubrac A, Soulet F, Lhomond S, Pallares-Lupon N, Prats H, Bikfalvi A, Chevet E, Touriol C, Moenner M. Oncotarget; 2015 Sep 22; 6(28):24922-34. PubMed ID: 26325176 [Abstract] [Full Text] [Related]
2. Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma. Auf G, Jabouille A, Guérit S, Pineau R, Delugin M, Bouchecareilh M, Magnin N, Favereaux A, Maitre M, Gaiser T, von Deimling A, Czabanka M, Vajkoczy P, Chevet E, Bikfalvi A, Moenner M. Proc Natl Acad Sci U S A; 2010 Aug 31; 107(35):15553-8. PubMed ID: 20702765 [Abstract] [Full Text] [Related]
3. High epiregulin expression in human U87 glioma cells relies on IRE1α and promotes autocrine growth through EGF receptor. Auf G, Jabouille A, Delugin M, Guérit S, Pineau R, North S, Platonova N, Maitre M, Favereaux A, Vajkoczy P, Seno M, Bikfalvi A, Minchenko D, Minchenko O, Moenner M. BMC Cancer; 2013 Dec 13; 13():597. PubMed ID: 24330607 [Abstract] [Full Text] [Related]
4. Autocrine control of glioma cells adhesion and migration through IRE1α-mediated cleavage of SPARC mRNA. Dejeans N, Pluquet O, Lhomond S, Grise F, Bouchecareilh M, Juin A, Meynard-Cadars M, Bidaud-Meynard A, Gentil C, Moreau V, Saltel F, Chevet E. J Cell Sci; 2012 Sep 15; 125(Pt 18):4278-87. PubMed ID: 22718352 [Abstract] [Full Text] [Related]
5. Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma. Kessler T, Sahm F, Blaes J, Osswald M, Rübmann P, Milford D, Urban S, Jestaedt L, Heiland S, Bendszus M, Hertenstein A, Pfenning PN, Ruiz de Almodóvar C, Wick A, Winkler F, von Deimling A, Platten M, Wick W, Weiler M. Oncotarget; 2015 Oct 13; 6(31):31050-68. PubMed ID: 25682871 [Abstract] [Full Text] [Related]
6. Inhibition of glioblastoma angiogenesis and invasion by combined treatments directed against vascular endothelial growth factor receptor-2, epidermal growth factor receptor, and vascular endothelial-cadherin. Lamszus K, Brockmann MA, Eckerich C, Bohlen P, May C, Mangold U, Fillbrandt R, Westphal M. Clin Cancer Res; 2005 Jul 01; 11(13):4934-40. PubMed ID: 16000592 [Abstract] [Full Text] [Related]
7. Long-Range Inhibitor-Induced Conformational Regulation of Human IRE1α Endoribonuclease Activity. Concha NO, Smallwood A, Bonnette W, Totoritis R, Zhang G, Federowicz K, Yang J, Qi H, Chen S, Campobasso N, Choudhry AE, Shuster LE, Evans KA, Ralph J, Sweitzer S, Heerding DA, Buser CA, Su DS, DeYoung MP. Mol Pharmacol; 2015 Dec 01; 88(6):1011-23. PubMed ID: 26438213 [Abstract] [Full Text] [Related]
8. Blockade of TGF-β signaling by the TGFβR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma. Zhang M, Kleber S, Röhrich M, Timke C, Han N, Tuettenberg J, Martin-Villalba A, Debus J, Peschke P, Wirkner U, Lahn M, Huber PE. Cancer Res; 2011 Dec 01; 71(23):7155-67. PubMed ID: 22006998 [Abstract] [Full Text] [Related]
9. Clustering of IRE1α depends on sensing ER stress but not on its RNase activity. Ricci D, Marrocco I, Blumenthal D, Dibos M, Eletto D, Vargas J, Boyle S, Iwamoto Y, Chomistek S, Paton JC, Paton AW, Argon Y. FASEB J; 2019 Sep 01; 33(9):9811-9827. PubMed ID: 31199681 [Abstract] [Full Text] [Related]
10. IRE1α Disruption in Triple-Negative Breast Cancer Cooperates with Antiangiogenic Therapy by Reversing ER Stress Adaptation and Remodeling the Tumor Microenvironment. Harnoss JM, Le Thomas A, Reichelt M, Guttman O, Wu TD, Marsters SA, Shemorry A, Lawrence DA, Kan D, Segal E, Merchant M, Totpal K, Crocker LM, Mesh K, Dohse M, Solon M, Modrusan Z, Rudolph J, Koeppen H, Walter P, Ashkenazi A. Cancer Res; 2020 Jun 01; 80(11):2368-2379. PubMed ID: 32265225 [Abstract] [Full Text] [Related]
11. Knockdown of IRE1α inhibits colonic tumorigenesis through decreasing β-catenin and IRE1α targeting suppresses colon cancer cells. Li XX, Zhang HS, Xu YM, Zhang RJ, Chen Y, Fan L, Qin YQ, Liu Y, Li M, Fang J. Oncogene; 2017 Nov 30; 36(48):6738-6746. PubMed ID: 28825721 [Abstract] [Full Text] [Related]
12. Multiple autophosphorylations significantly enhance the endoribonuclease activity of human inositol requiring enzyme 1α. Itzhak D, Bright M, McAndrew P, Mirza A, Newbatt Y, Strover J, Widya M, Thompson A, Morgan G, Collins I, Davies F. BMC Biochem; 2014 Feb 13; 15():3. PubMed ID: 24524643 [Abstract] [Full Text] [Related]
13. Dual IRE1 RNase functions dictate glioblastoma development. Lhomond S, Avril T, Dejeans N, Voutetakis K, Doultsinos D, McMahon M, Pineau R, Obacz J, Papadodima O, Jouan F, Bourien H, Logotheti M, Jégou G, Pallares-Lupon N, Schmit K, Le Reste PJ, Etcheverry A, Mosser J, Barroso K, Vauléon E, Maurel M, Samali A, Patterson JB, Pluquet O, Hetz C, Quillien V, Chatziioannou A, Chevet E. EMBO Mol Med; 2018 Mar 13; 10(3):. PubMed ID: 29311133 [Abstract] [Full Text] [Related]
14. Profiling the Dual Enzymatic Activities of the Serine/Threonine Kinase IRE1α. Feldman HC, Maly DJ. Methods Mol Biol; 2017 Mar 13; 1513():233-242. PubMed ID: 27807842 [Abstract] [Full Text] [Related]
15. A kinase inhibitor activates the IRE1alpha RNase to confer cytoprotection against ER stress. Han D, Upton JP, Hagen A, Callahan J, Oakes SA, Papa FR. Biochem Biophys Res Commun; 2008 Jan 25; 365(4):777-83. PubMed ID: 18035051 [Abstract] [Full Text] [Related]
16. Curcumin inhibits tumor growth and angiogenesis in glioblastoma xenografts. Perry MC, Demeule M, Régina A, Moumdjian R, Béliveau R. Mol Nutr Food Res; 2010 Aug 25; 54(8):1192-201. PubMed ID: 20087857 [Abstract] [Full Text] [Related]
17. Juglone reduces growth and migration of U251 glioblastoma cells and disrupts angiogenesis. Wang J, Liu K, Wang XF, Sun DJ. Oncol Rep; 2017 Oct 25; 38(4):1959-1966. PubMed ID: 28791366 [Abstract] [Full Text] [Related]
18. Regulation of chondrocyte differentiation by IRE1α depends on its enzymatic activity. Guo FJ, Jiang R, Li X, Zhang P, Han X, Liu C. Cell Signal; 2014 Sep 25; 26(9):1998-2007. PubMed ID: 24863879 [Abstract] [Full Text] [Related]
19. Structural and Functional Analysis of the Allosteric Inhibition of IRE1α with ATP-Competitive Ligands. Feldman HC, Tong M, Wang L, Meza-Acevedo R, Gobillot TA, Lebedev I, Gliedt MJ, Hari SB, Mitra AK, Backes BJ, Papa FR, Seeliger MA, Maly DJ. ACS Chem Biol; 2016 Aug 19; 11(8):2195-205. PubMed ID: 27227314 [Abstract] [Full Text] [Related]
20. Effect of human skin-derived stem cells on vessel architecture, tumor growth, and tumor invasion in brain tumor animal models. Pisati F, Belicchi M, Acerbi F, Marchesi C, Giussani C, Gavina M, Javerzat S, Hagedorn M, Carrabba G, Lucini V, Gaini SM, Bresolin N, Bello L, Bikfalvi A, Torrente Y. Cancer Res; 2007 Apr 01; 67(7):3054-63. PubMed ID: 17409412 [Abstract] [Full Text] [Related] Page: [Next] [New Search]