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208 related items for PubMed ID: 26334669

  • 1. cAMP signalling of Bordetella adenylate cyclase toxin through the SHP-1 phosphatase activates the BimEL-Bax pro-apoptotic cascade in phagocytes.
    Ahmad JN, Cerny O, Linhartova I, Masin J, Osicka R, Sebo P.
    Cell Microbiol; 2016 Mar; 18(3):384-98. PubMed ID: 26334669
    [Abstract] [Full Text] [Related]

  • 2. Bordetella pertussis Adenylate Cyclase Toxin Blocks Induction of Bactericidal Nitric Oxide in Macrophages through cAMP-Dependent Activation of the SHP-1 Phosphatase.
    Cerny O, Kamanova J, Masin J, Bibova I, Skopova K, Sebo P.
    J Immunol; 2015 May 15; 194(10):4901-13. PubMed ID: 25876760
    [Abstract] [Full Text] [Related]

  • 3. Cyclic AMP-Elevating Capacity of Adenylate Cyclase Toxin-Hemolysin Is Sufficient for Lung Infection but Not for Full Virulence of Bordetella pertussis.
    Skopova K, Tomalova B, Kanchev I, Rossmann P, Svedova M, Adkins I, Bibova I, Tomala J, Masin J, Guiso N, Osicka R, Sedlacek R, Kovar M, Sebo P.
    Infect Immun; 2017 Jun 15; 85(6):. PubMed ID: 28396322
    [Abstract] [Full Text] [Related]

  • 4. Bordetella Adenylate Cyclase Toxin Inhibits Monocyte-to-Macrophage Transition and Dedifferentiates Human Alveolar Macrophages into Monocyte-like Cells.
    Ahmad JN, Holubova J, Benada O, Kofronova O, Stehlik L, Vasakova M, Sebo P.
    mBio; 2019 Sep 24; 10(5):. PubMed ID: 31551332
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  • 6. Bordetella adenylate cyclase toxin: a unique combination of a pore-forming moiety with a cell-invading adenylate cyclase enzyme.
    Masin J, Osicka R, Bumba L, Sebo P.
    Pathog Dis; 2015 Nov 24; 73(8):ftv075. PubMed ID: 26391732
    [Abstract] [Full Text] [Related]

  • 7. Transmembrane segments of complement receptor 3 do not participate in cytotoxic activities but determine receptor structure required for action of Bordetella adenylate cyclase toxin.
    Wald T, Osickova A, Masin J, Liskova PM, Petry-Podgorska I, Matousek T, Sebo P, Osicka R.
    Pathog Dis; 2016 Apr 24; 74(3):. PubMed ID: 26802078
    [Abstract] [Full Text] [Related]

  • 8. cAMP Signaling of Adenylate Cyclase Toxin Blocks the Oxidative Burst of Neutrophils through Epac-Mediated Inhibition of Phospholipase C Activity.
    Cerny O, Anderson KE, Stephens LR, Hawkins PT, Sebo P.
    J Immunol; 2017 Feb 01; 198(3):1285-1296. PubMed ID: 28039302
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  • 9. Structure-Function Relationships Underlying the Capacity of Bordetella Adenylate Cyclase Toxin to Disarm Host Phagocytes.
    Novak J, Cerny O, Osickova A, Linhartova I, Masin J, Bumba L, Sebo P, Osicka R.
    Toxins (Basel); 2017 Sep 24; 9(10):. PubMed ID: 28946636
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  • 11. Adenylate cyclase toxin subverts phagocyte function by RhoA inhibition and unproductive ruffling.
    Kamanova J, Kofronova O, Masin J, Genth H, Vojtova J, Linhartova I, Benada O, Just I, Sebo P.
    J Immunol; 2008 Oct 15; 181(8):5587-97. PubMed ID: 18832717
    [Abstract] [Full Text] [Related]

  • 12. Pore-forming and enzymatic activities of Bordetella pertussis adenylate cyclase toxin synergize in promoting lysis of monocytes.
    Basler M, Masin J, Osicka R, Sebo P.
    Infect Immun; 2006 Apr 15; 74(4):2207-14. PubMed ID: 16552051
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  • 13. The adenylate cyclase toxin of Bordetella pertussis binds to target cells via the alpha(M)beta(2) integrin (CD11b/CD18).
    Guermonprez P, Khelef N, Blouin E, Rieu P, Ricciardi-Castagnoli P, Guiso N, Ladant D, Leclerc C.
    J Exp Med; 2001 May 07; 193(9):1035-44. PubMed ID: 11342588
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  • 14. Third activity of Bordetella adenylate cyclase (AC) toxin-hemolysin. Membrane translocation of AC domain polypeptide promotes calcium influx into CD11b+ monocytes independently of the catalytic and hemolytic activities.
    Fiser R, Masín J, Basler M, Krusek J, Spuláková V, Konopásek I, Sebo P.
    J Biol Chem; 2007 Feb 02; 282(5):2808-20. PubMed ID: 17148436
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  • 15. Ca2+ influx and tyrosine kinases trigger Bordetella adenylate cyclase toxin (ACT) endocytosis. Cell physiology and expression of the CD11b/CD18 integrin major determinants of the entry route.
    Uribe KB, Martín C, Etxebarria A, González-Bullón D, Gómez-Bilbao G, Ostolaza H.
    PLoS One; 2013 Feb 02; 8(9):e74248. PubMed ID: 24058533
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  • 16. Phospholipase A activity of adenylate cyclase toxin mediates translocation of its adenylate cyclase domain.
    González-Bullón D, Uribe KB, Martín C, Ostolaza H.
    Proc Natl Acad Sci U S A; 2017 Aug 15; 114(33):E6784-E6793. PubMed ID: 28760979
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  • 17. Bordetella adenylate cyclase toxin: a swift saboteur of host defense.
    Vojtova J, Kamanova J, Sebo P.
    Curr Opin Microbiol; 2006 Feb 15; 9(1):69-75. PubMed ID: 16406775
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  • 18. Bordetella pertussis Adenylate Cyclase Toxin Disrupts Functional Integrity of Bronchial Epithelial Layers.
    Hasan S, Kulkarni NN, Asbjarnarson A, Linhartova I, Osicka R, Sebo P, Gudmundsson GH.
    Infect Immun; 2018 Mar 15; 86(3):. PubMed ID: 29203545
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  • 20. Bordetella adenylate cyclase toxin is a unique ligand of the integrin complement receptor 3.
    Osicka R, Osickova A, Hasan S, Bumba L, Cerny J, Sebo P.
    Elife; 2015 Dec 09; 4():e10766. PubMed ID: 26650353
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