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219 related items for PubMed ID: 26348575

  • 1. Fibrosis and hypoxia-inducible factor-1α-dependent tumors of the soft tissue on loss of von Hippel-Lindau in mesenchymal progenitors.
    Mangiavini L, Merceron C, Araldi E, Khatri R, Gerard-O'Riley R, Wilson TL, Sandusky G, Abadie J, Lyons KM, Giaccia AJ, Schipani E.
    Am J Pathol; 2015 Nov; 185(11):3090-101. PubMed ID: 26348575
    [Abstract] [Full Text] [Related]

  • 2. Loss of VHL in mesenchymal progenitors of the limb bud alters multiple steps of endochondral bone development.
    Mangiavini L, Merceron C, Araldi E, Khatri R, Gerard-O'Riley R, Wilson TL, Rankin EB, Giaccia AJ, Schipani E.
    Dev Biol; 2014 Sep 01; 393(1):124-36. PubMed ID: 24972088
    [Abstract] [Full Text] [Related]

  • 3. Expression of hypoxia-inducible factor 1alpha, hypoxia-inducible factor 2alpha, and von Hippel-Lindau protein in epithelial ovarian neoplasms and allelic loss of von Hippel-Lindau gene: nuclear expression of hypoxia-inducible factor 1alpha is an independent prognostic factor in ovarian carcinoma.
    Osada R, Horiuchi A, Kikuchi N, Yoshida J, Hayashi A, Ota M, Katsuyama Y, Melillo G, Konishi I.
    Hum Pathol; 2007 Sep 01; 38(9):1310-20. PubMed ID: 17555795
    [Abstract] [Full Text] [Related]

  • 4. Up-regulation of hypoxia-inducible factors HIF-1alpha and HIF-2alpha under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function.
    Krieg M, Haas R, Brauch H, Acker T, Flamme I, Plate KH.
    Oncogene; 2000 Nov 16; 19(48):5435-43. PubMed ID: 11114720
    [Abstract] [Full Text] [Related]

  • 5. The relationship of erythropoietin overexpression with von Hippel-Lindau tumour suppressor gene mutations between hypoxia-inducible factor-1α and -2α in sporadic clear cell renal carcinoma.
    Gong K, Zhang N, Zhang K, Na Y.
    Int J Mol Med; 2010 Dec 16; 26(6):907-12. PubMed ID: 21042786
    [Abstract] [Full Text] [Related]

  • 6. Role of hypoxia-inducible factor (HIF)-1alpha versus HIF-2alpha in the regulation of HIF target genes in response to hypoxia, insulin-like growth factor-I, or loss of von Hippel-Lindau function: implications for targeting the HIF pathway.
    Carroll VA, Ashcroft M.
    Cancer Res; 2006 Jun 15; 66(12):6264-70. PubMed ID: 16778202
    [Abstract] [Full Text] [Related]

  • 7. Hypoxia, Hypoxia-inducible Transcription Factors, and Renal Cancer.
    Schödel J, Grampp S, Maher ER, Moch H, Ratcliffe PJ, Russo P, Mole DR.
    Eur Urol; 2016 Apr 15; 69(4):646-657. PubMed ID: 26298207
    [Abstract] [Full Text] [Related]

  • 8. Reduction of hepatic fibrosis by overexpression of von Hippel-Lindau protein in experimental models of chronic liver disease.
    Wang J, Lu Z, Xu Z, Tian P, Miao H, Pan S, Song R, Sun X, Zhao B, Wang D, Ma Y, Song X, Zhang S, Liu L, Jiang H.
    Sci Rep; 2017 Jan 23; 7():41038. PubMed ID: 28112200
    [Abstract] [Full Text] [Related]

  • 9. Action of hypoxia-inducible factor in liver and kidney from mice with Pax8-rtTA-based deletion of von Hippel-Lindau protein.
    Mathia S, Paliege A, Koesters R, Peters H, Neumayer HH, Bachmann S, Rosenberger C.
    Acta Physiol (Oxf); 2013 Mar 23; 207(3):565-76. PubMed ID: 23384425
    [Abstract] [Full Text] [Related]

  • 10. Epigenetic regulation of HIF-1α in renal cancer cells involves HIF-1α/2α binding to a reverse hypoxia-response element.
    Xu J, Wang B, Xu Y, Sun L, Tian W, Shukla D, Barod R, Grillari J, Grillari-Voglauer R, Maxwell PH, Esteban MA.
    Oncogene; 2012 Feb 23; 31(8):1065-72. PubMed ID: 21841824
    [Abstract] [Full Text] [Related]

  • 11. Renal tubular HIF-2α expression requires VHL inactivation and causes fibrosis and cysts.
    Schietke RE, Hackenbeck T, Tran M, Günther R, Klanke B, Warnecke CL, Knaup KX, Shukla D, Rosenberger C, Koesters R, Bachmann S, Betz P, Schley G, Schödel J, Willam C, Winkler T, Amann K, Eckardt KU, Maxwell P, Wiesener MS.
    PLoS One; 2012 Feb 23; 7(1):e31034. PubMed ID: 22299048
    [Abstract] [Full Text] [Related]

  • 12. Hypoxia-inducible factor augments experimental colitis through an MIF-dependent inflammatory signaling cascade.
    Shah YM, Ito S, Morimura K, Chen C, Yim SH, Haase VH, Gonzalez FJ.
    Gastroenterology; 2008 Jun 23; 134(7):2036-48, 2048.e1-3. PubMed ID: 18439915
    [Abstract] [Full Text] [Related]

  • 13. Prolyl hydroxylase 2 dependent and Von-Hippel-Lindau independent degradation of Hypoxia-inducible factor 1 and 2 alpha by selenium in clear cell renal cell carcinoma leads to tumor growth inhibition.
    Chintala S, Najrana T, Toth K, Cao S, Durrani FA, Pili R, Rustum YM.
    BMC Cancer; 2012 Jul 17; 12():293. PubMed ID: 22804960
    [Abstract] [Full Text] [Related]

  • 14. Hypoxia-inducible factor-dependent degeneration, failure, and malignant transformation of the heart in the absence of the von Hippel-Lindau protein.
    Lei L, Mason S, Liu D, Huang Y, Marks C, Hickey R, Jovin IS, Pypaert M, Johnson RS, Giordano FJ.
    Mol Cell Biol; 2008 Jun 17; 28(11):3790-803. PubMed ID: 18285456
    [Abstract] [Full Text] [Related]

  • 15. Role of VHL, HIF1A and SDH on the expression of miR-210: Implications for tumoral pseudo-hypoxic fate.
    Merlo A, Bernardo-Castiñeira C, Sáenz-de-Santa-María I, Pitiot AS, Balbín M, Astudillo A, Valdés N, Scola B, Del Toro R, Méndez-Ferrer S, Piruat JI, Suarez C, Chiara MD.
    Oncotarget; 2017 Jan 24; 8(4):6700-6717. PubMed ID: 28036268
    [Abstract] [Full Text] [Related]

  • 16. Loss of von Hippel-Lindau protein (VHL) increases systemic cholesterol levels through targeting hypoxia-inducible factor 2α and regulation of bile acid homeostasis.
    Ramakrishnan SK, Taylor M, Qu A, Ahn SH, Suresh MV, Raghavendran K, Gonzalez FJ, Shah YM.
    Mol Cell Biol; 2014 Apr 24; 34(7):1208-20. PubMed ID: 24421394
    [Abstract] [Full Text] [Related]

  • 17. Identification of Ror2 as a hypoxia-inducible factor target in von Hippel-Lindau-associated renal cell carcinoma.
    Wright TM, Rathmell WK.
    J Biol Chem; 2010 Apr 23; 285(17):12916-24. PubMed ID: 20185829
    [Abstract] [Full Text] [Related]

  • 18. The role of aberrant VHL/HIF pathway elements in predicting clinical outcome to pazopanib therapy in patients with metastatic clear-cell renal cell carcinoma.
    Choueiri TK, Fay AP, Gagnon R, Lin Y, Bahamon B, Brown V, Rosenberg JE, Hutson TE, Baker-Neblett KL, Carpenter C, Liu Y, Pandite L, Signoretti S.
    Clin Cancer Res; 2013 Sep 15; 19(18):5218-26. PubMed ID: 23881929
    [Abstract] [Full Text] [Related]

  • 19. Research resource: Transcriptional profiling reveals different pseudohypoxic signatures in SDHB and VHL-related pheochromocytomas.
    López-Jiménez E, Gómez-López G, Leandro-García LJ, Muñoz I, Schiavi F, Montero-Conde C, de Cubas AA, Ramires R, Landa I, Leskelä S, Maliszewska A, Inglada-Pérez L, de la Vega L, Rodríguez-Antona C, Letón R, Bernal C, de Campos JM, Diez-Tascón C, Fraga MF, Boullosa C, Pisano DG, Opocher G, Robledo M, Cascón A.
    Mol Endocrinol; 2010 Dec 15; 24(12):2382-91. PubMed ID: 20980436
    [Abstract] [Full Text] [Related]

  • 20. von Hippel-Lindau mutation in mice recapitulates Chuvash polycythemia via hypoxia-inducible factor-2alpha signaling and splenic erythropoiesis.
    Hickey MM, Lam JC, Bezman NA, Rathmell WK, Simon MC.
    J Clin Invest; 2007 Dec 15; 117(12):3879-89. PubMed ID: 17992257
    [Abstract] [Full Text] [Related]

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