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Journal Abstract Search
395 related items for PubMed ID: 26359498
1. Shedding of Endogenous Interleukin-6 Receptor (IL-6R) Is Governed by A Disintegrin and Metalloproteinase (ADAM) Proteases while a Full-length IL-6R Isoform Localizes to Circulating Microvesicles. Schumacher N, Meyer D, Mauermann A, von der Heyde J, Wolf J, Schwarz J, Knittler K, Murphy G, Michalek M, Garbers C, Bartsch JW, Guo S, Schacher B, Eickholz P, Chalaris A, Rose-John S, Rabe B. J Biol Chem; 2015 Oct 23; 290(43):26059-71. PubMed ID: 26359498 [Abstract] [Full Text] [Related]
5. Species specificity of ADAM10 and ADAM17 proteins in interleukin-6 (IL-6) trans-signaling and novel role of ADAM10 in inducible IL-6 receptor shedding. Garbers C, Jänner N, Chalaris A, Moss ML, Floss DM, Meyer D, Koch-Nolte F, Rose-John S, Scheller J. J Biol Chem; 2011 Apr 29; 286(17):14804-11. PubMed ID: 21454673 [Abstract] [Full Text] [Related]
9. Cutting edge: soluble IL-6R is produced by IL-6R ectodomain shedding in activated CD4 T cells. Briso EM, Dienz O, Rincon M. J Immunol; 2008 Jun 01; 180(11):7102-6. PubMed ID: 18490707 [Abstract] [Full Text] [Related]
10. Proteolytic Origin of the Soluble Human IL-6R In Vivo and a Decisive Role of N-Glycosylation. Riethmueller S, Somasundaram P, Ehlers JC, Hung CW, Flynn CM, Lokau J, Agthe M, Düsterhöft S, Zhu Y, Grötzinger J, Lorenzen I, Koudelka T, Yamamoto K, Pickhinke U, Wichert R, Becker-Pauly C, Rädisch M, Albrecht A, Hessefort M, Stahnke D, Unverzagt C, Rose-John S, Tholey A, Garbers C. PLoS Biol; 2017 Jan 01; 15(1):e2000080. PubMed ID: 28060820 [Abstract] [Full Text] [Related]
11. Meprin Metalloproteases Generate Biologically Active Soluble Interleukin-6 Receptor to Induce Trans-Signaling. Arnold P, Boll I, Rothaug M, Schumacher N, Schmidt F, Wichert R, Schneppenheim J, Lokau J, Pickhinke U, Koudelka T, Tholey A, Rabe B, Scheller J, Lucius R, Garbers C, Rose-John S, Becker-Pauly C. Sci Rep; 2017 Mar 09; 7():44053. PubMed ID: 28276471 [Abstract] [Full Text] [Related]
12. Cellular senescence or EGFR signaling induces Interleukin 6 (IL-6) receptor expression controlled by mammalian target of rapamycin (mTOR). Garbers C, Kuck F, Aparicio-Siegmund S, Konzak K, Kessenbrock M, Sommerfeld A, Häussinger D, Lang PA, Brenner D, Mak TW, Rose-John S, Essmann F, Schulze-Osthoff K, Piekorz RP, Scheller J. Cell Cycle; 2013 Nov 01; 12(21):3421-32. PubMed ID: 24047696 [Abstract] [Full Text] [Related]
13. The Antiatherogenic Effect of Fish Oil in Male Mice Is Associated with a Diminished Release of Endothelial ADAM17 and ADAM10 Substrates. Speck N, Brandsch C, Schmidt N, Yazdekhasti N, Hirche F, Lucius R, Rimbach G, Stangl GI, Reiss K. J Nutr; 2015 Jun 01; 145(6):1218-26. PubMed ID: 25926412 [Abstract] [Full Text] [Related]
14. Proteolytic Cleavage Governs Interleukin-11 Trans-signaling. Lokau J, Nitz R, Agthe M, Monhasery N, Aparicio-Siegmund S, Schumacher N, Wolf J, Möller-Hackbarth K, Waetzig GH, Grötzinger J, Müller-Newen G, Rose-John S, Scheller J, Garbers C. Cell Rep; 2016 Feb 23; 14(7):1761-1773. PubMed ID: 26876177 [Abstract] [Full Text] [Related]
15. Different Soluble Forms of the Interleukin-6 Family Signal Transducer gp130 Fine-tune the Blockade of Interleukin-6 Trans-signaling. Wolf J, Waetzig GH, Chalaris A, Reinheimer TM, Wege H, Rose-John S, Garbers C. J Biol Chem; 2016 Jul 29; 291(31):16186-96. PubMed ID: 27226573 [Abstract] [Full Text] [Related]
16. Role of ADAM10 and ADAM17 in CD16b shedding mediated by different stimulators. Guo S, Peng M, Zhao Q, Zhang W. Chin Med Sci J; 2012 Jun 29; 27(2):73-9. PubMed ID: 22770404 [Abstract] [Full Text] [Related]
18. Proteolytically active ADAM10 and ADAM17 carried on membrane microvesicles in human abdominal aortic aneurysms. Folkesson M, Li C, Frebelius S, Swedenborg J, Wågsäter D, Williams KJ, Eriksson P, Roy J, Liu ML. Thromb Haemost; 2015 Nov 25; 114(6):1165-74. PubMed ID: 26422658 [Abstract] [Full Text] [Related]
19. Metalloproteinase inhibitors for the disintegrin-like metalloproteinases ADAM10 and ADAM17 that differentially block constitutive and phorbol ester-inducible shedding of cell surface molecules. Ludwig A, Hundhausen C, Lambert MH, Broadway N, Andrews RC, Bickett DM, Leesnitzer MA, Becherer JD. Comb Chem High Throughput Screen; 2005 Mar 25; 8(2):161-71. PubMed ID: 15777180 [Abstract] [Full Text] [Related]