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265 related items for PubMed ID: 26363783

  • 1. Protein kinase Cδ regulates nuclear export of FOXO1 through phosphorylation of the chaperone 14-3-3ζ.
    Gerst F, Kaiser G, Panse M, Sartorius T, Pujol A, Hennige AM, Machicao F, Lammers R, Bosch F, Häring HU, Ullrich S.
    Diabetologia; 2015 Dec; 58(12):2819-31. PubMed ID: 26363783
    [Abstract] [Full Text] [Related]

  • 2. Overexpression of kinase-negative protein kinase Cdelta in pancreatic beta-cells protects mice from diet-induced glucose intolerance and beta-cell dysfunction.
    Hennige AM, Ranta F, Heinzelmann I, Düfer M, Michael D, Braumüller H, Lutz SZ, Lammers R, Drews G, Bosch F, Häring HU, Ullrich S.
    Diabetes; 2010 Jan; 59(1):119-27. PubMed ID: 19826167
    [Abstract] [Full Text] [Related]

  • 3. Regulation of forkhead box O1 (FOXO1) by protein kinase B and glucocorticoids: different mechanisms of induction of beta cell death in vitro.
    Kaiser G, Gerst F, Michael D, Berchtold S, Friedrich B, Strutz-Seebohm N, Lang F, Häring HU, Ullrich S.
    Diabetologia; 2013 Jul; 56(7):1587-95. PubMed ID: 23435785
    [Abstract] [Full Text] [Related]

  • 4. Protein kinase C delta (PKCδ) affects proliferation of insulin-secreting cells by promoting nuclear extrusion of the cell cycle inhibitor p21Cip1/WAF1.
    Ranta F, Leveringhaus J, Theilig D, Schulz-Raffelt G, Hennige AM, Hildebrand DG, Handrick R, Jendrossek V, Bosch F, Schulze-Osthoff K, Häring HU, Ullrich S.
    PLoS One; 2011 Jul; 6(12):e28828. PubMed ID: 22216119
    [Abstract] [Full Text] [Related]

  • 5. Glucose regulates Foxo1 through insulin receptor signaling in the pancreatic islet beta-cell.
    Martinez SC, Cras-Méneur C, Bernal-Mizrachi E, Permutt MA.
    Diabetes; 2006 Jun; 55(6):1581-91. PubMed ID: 16731820
    [Abstract] [Full Text] [Related]

  • 6. Nucleo-cytosolic shuttling of FoxO1 directly regulates mouse Ins2 but not Ins1 gene expression in pancreatic beta cells (MIN6).
    Meur G, Qian Q, da Silva Xavier G, Pullen TJ, Tsuboi T, McKinnon C, Fletcher L, Tavaré JM, Hughes S, Johnson P, Rutter GA.
    J Biol Chem; 2011 Apr 15; 286(15):13647-56. PubMed ID: 21335550
    [Abstract] [Full Text] [Related]

  • 7. Apolipoprotein A-I increases insulin secretion and production from pancreatic β-cells via a G-protein-cAMP-PKA-FoxO1-dependent mechanism.
    Cochran BJ, Bisoendial RJ, Hou L, Glaros EN, Rossy J, Thomas SR, Barter PJ, Rye KA.
    Arterioscler Thromb Vasc Biol; 2014 Oct 15; 34(10):2261-7. PubMed ID: 25147338
    [Abstract] [Full Text] [Related]

  • 8. Forkhead box O1/pancreatic and duodenal homeobox 1 intracellular translocation is regulated by c-Jun N-terminal kinase and involved in prostaglandin E2-induced pancreatic beta-cell dysfunction.
    Meng Z, Lv J, Luo Y, Lin Y, Zhu Y, Nie J, Yang T, Sun Y, Han X.
    Endocrinology; 2009 Dec 15; 150(12):5284-93. PubMed ID: 19837872
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.
    Martinez SC, Tanabe K, Cras-Méneur C, Abumrad NA, Bernal-Mizrachi E, Permutt MA.
    Diabetes; 2008 Apr 15; 57(4):846-59. PubMed ID: 18174526
    [Abstract] [Full Text] [Related]

  • 10. Glucose-dependent insulinotropic polypeptide (GIP) stimulation of pancreatic beta-cell survival is dependent upon phosphatidylinositol 3-kinase (PI3K)/protein kinase B (PKB) signaling, inactivation of the forkhead transcription factor Foxo1, and down-regulation of bax expression.
    Kim SJ, Winter K, Nian C, Tsuneoka M, Koda Y, McIntosh CH.
    J Biol Chem; 2005 Jun 10; 280(23):22297-307. PubMed ID: 15817464
    [Abstract] [Full Text] [Related]

  • 11. Inhibition of Foxo1 mediates protective effects of ghrelin against lipotoxicity in MIN6 pancreatic beta-cells.
    Wang W, Liu Y, Chen Y, Cao C, Xiang Y, Zhang D, Han L, Zhao H, Liu G.
    Peptides; 2010 Feb 10; 31(2):307-14. PubMed ID: 19944124
    [Abstract] [Full Text] [Related]

  • 12. LRP16 gene protects mouse insulinoma MIN6 cells against fatty acid-induced apoptosis through Akt/FoxO1 signaling.
    Li XJ, Guo QH, Wang X, Xue B, Sun LQ, Meng QT, Lu JM, Mu YM.
    Chin Med J (Engl); 2012 May 10; 125(10):1695-702. PubMed ID: 22800886
    [Abstract] [Full Text] [Related]

  • 13. The forkhead transcription factor Foxo1 bridges the JNK pathway and the transcription factor PDX-1 through its intracellular translocation.
    Kawamori D, Kaneto H, Nakatani Y, Matsuoka TA, Matsuhisa M, Hori M, Yamasaki Y.
    J Biol Chem; 2006 Jan 13; 281(2):1091-8. PubMed ID: 16282329
    [Abstract] [Full Text] [Related]

  • 14. FoxO1 Plays an Important Role in Regulating β-Cell Compensation for Insulin Resistance in Male Mice.
    Zhang T, Kim DH, Xiao X, Lee S, Gong Z, Muzumdar R, Calabuig-Navarro V, Yamauchi J, Harashima H, Wang R, Bottino R, Alvarez-Perez JC, Garcia-Ocaña A, Gittes G, Dong HH.
    Endocrinology; 2016 Mar 13; 157(3):1055-70. PubMed ID: 26727107
    [Abstract] [Full Text] [Related]

  • 15. Forkhead box O1 mediates defects in palmitate-induced insulin granule exocytosis by downregulation of calcium/calmodulin-dependent serine protein kinase expression in INS-1 cells.
    Wang Y, Lin H, Hao N, Zhu Z, Wang D, Li Y, Chen H, Zhu Y, Han X.
    Diabetologia; 2015 Jun 13; 58(6):1272-81. PubMed ID: 25796372
    [Abstract] [Full Text] [Related]

  • 16. The B55α-containing PP2A holoenzyme dephosphorylates FOXO1 in islet β-cells under oxidative stress.
    Yan L, Guo S, Brault M, Harmon J, Robertson RP, Hamid R, Stein R, Yang E.
    Biochem J; 2012 Jun 01; 444(2):239-47. PubMed ID: 22417654
    [Abstract] [Full Text] [Related]

  • 17. Peroxisome proliferator-activated receptorβ/δ activation is essential for modulating p-Foxo1/Foxo1 status in functional insulin-positive cell differentiation.
    Li L, Li T, Zhang Y, Pan Z, Wu B, Huang X, Zhang Y, Mei Y, Ge L, Shen G, Ge RS, Zhu D, Lou Y.
    Cell Death Dis; 2015 Apr 09; 6(4):e1715. PubMed ID: 25855963
    [Abstract] [Full Text] [Related]

  • 18. Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure.
    Kluth O, Mirhashemi F, Scherneck S, Kaiser D, Kluge R, Neschen S, Joost HG, Schürmann A.
    Diabetologia; 2011 Mar 09; 54(3):605-16. PubMed ID: 21107520
    [Abstract] [Full Text] [Related]

  • 19. Translocation of forkhead box O1 to the nuclear periphery induces histone modifications that regulate transcriptional repression of PCK1 in HepG2 cells.
    Arai T, Kano F, Murata M.
    Genes Cells; 2015 Apr 09; 20(4):340-57. PubMed ID: 25736587
    [Abstract] [Full Text] [Related]

  • 20. Mathematical modeling reveals modulation of both nuclear influx and efflux of Foxo1 by the IGF-I/PI3K/Akt pathway in skeletal muscle fibers.
    Wimmer RJ, Liu Y, Schachter TN, Stonko DP, Peercy BE, Schneider MF.
    Am J Physiol Cell Physiol; 2014 Mar 15; 306(6):C570-84. PubMed ID: 24429066
    [Abstract] [Full Text] [Related]

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