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Journal Abstract Search

557 related items for PubMed ID: 26381178

  • 1. PF-4708671, a specific inhibitor of p70 ribosomal S6 kinase 1, activates Nrf2 by promoting p62-dependent autophagic degradation of Keap1.
    Park JS, Kang DH, Lee DH, Bae SH.
    Biochem Biophys Res Commun; 2015 Oct 23; 466(3):499-504. PubMed ID: 26381178
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  • 9. p62/SQSTM1 is a target gene for transcription factor NRF2 and creates a positive feedback loop by inducing antioxidant response element-driven gene transcription.
    Jain A, Lamark T, Sjøttem E, Larsen KB, Awuh JA, Øvervatn A, McMahon M, Hayes JD, Johansen T.
    J Biol Chem; 2010 Jul 16; 285(29):22576-91. PubMed ID: 20452972
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  • 10. The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
    Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M.
    Nat Cell Biol; 2010 Mar 16; 12(3):213-23. PubMed ID: 20173742
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  • 13. Dissection of the role of p62/Sqstm1 in activation of Nrf2 during xenophagy.
    Ishimura R, Tanaka K, Komatsu M.
    FEBS Lett; 2014 Mar 03; 588(5):822-8. PubMed ID: 24492006
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  • 16. Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies.
    Duleh S, Wang X, Komirenko A, Margeta M.
    Acta Neuropathol Commun; 2016 Oct 31; 4(1):115. PubMed ID: 27799074
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  • 17. A noncanonical mechanism of Nrf2 activation by autophagy deficiency: direct interaction between Keap1 and p62.
    Lau A, Wang XJ, Zhao F, Villeneuve NF, Wu T, Jiang T, Sun Z, White E, Zhang DD.
    Mol Cell Biol; 2010 Jul 31; 30(13):3275-85. PubMed ID: 20421418
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  • 18. The hypertension drug, verapamil, activates Nrf2 by promoting p62-dependent autophagic Keap1 degradation and prevents acetaminophen-induced cytotoxicity.
    Lee DH, Park JS, Lee YS, Sung SH, Lee YH, Bae SH.
    BMB Rep; 2017 Feb 31; 50(2):91-96. PubMed ID: 27998394
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  • 19. p62/SQSTM1 functions as a signaling hub and an autophagy adaptor.
    Katsuragi Y, Ichimura Y, Komatsu M.
    FEBS J; 2015 Dec 31; 282(24):4672-8. PubMed ID: 26432171
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  • 20. p62/SQSTM1 protects against cisplatin-induced oxidative stress in kidneys by mediating the cross talk between autophagy and the Keap1-Nrf2 signalling pathway.
    Liao W, Wang Z, Fu Z, Ma H, Jiang M, Xu A, Zhang W.
    Free Radic Res; 2019 Jul 31; 53(7):800-814. PubMed ID: 31223046
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