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1205 related items for PubMed ID: 26420645

  • 1. Continuous activation of Nrf2 and its target antioxidant enzymes leads to arsenite-induced malignant transformation of human bronchial epithelial cells.
    Yang X, Wang D, Ma Y, Xu X, Zhu Z, Wang X, Deng H, Li C, Chen M, Tong J, Yamanaka K, An Y.
    Toxicol Appl Pharmacol; 2015 Dec 01; 289(2):231-9. PubMed ID: 26420645
    [Abstract] [Full Text] [Related]

  • 2. Hypermethylation of the Keap1 gene inactivates its function, promotes Nrf2 nuclear accumulation, and is involved in arsenite-induced human keratinocyte transformation.
    Wang D, Ma Y, Yang X, Xu X, Zhao Y, Zhu Z, Wang X, Deng H, Li C, Gao F, Tong J, Yamanaka K, An Y.
    Free Radic Biol Med; 2015 Dec 01; 89():209-19. PubMed ID: 26409248
    [Abstract] [Full Text] [Related]

  • 3. MicroRNA-155 regulates arsenite-induced malignant transformation by targeting Nrf2-mediated oxidative damage in human bronchial epithelial cells.
    Chen C, Jiang X, Gu S, Zhang Z.
    Toxicol Lett; 2017 Aug 15; 278():38-47. PubMed ID: 28688901
    [Abstract] [Full Text] [Related]

  • 4. MicroRNA-21, up-regulated by arsenite, directs the epithelial-mesenchymal transition and enhances the invasive potential of transformed human bronchial epithelial cells by targeting PDCD4.
    Luo F, Ji J, Liu Y, Xu Y, Zheng G, Jing J, Wang B, Xu W, Shi L, Lu X, Liu Q.
    Toxicol Lett; 2015 Jan 05; 232(1):301-9. PubMed ID: 25445583
    [Abstract] [Full Text] [Related]

  • 5. [Role of nuclear factor E2 related factor 2 signaling pathway in malignant transformation induced by sodium arsenite].
    Gu S, Chen C, Jiang X, Zhang Z.
    Wei Sheng Yan Jiu; 2016 May 05; 45(3):356-61. PubMed ID: 27459794
    [Abstract] [Full Text] [Related]

  • 6. Nrf2/p62 signaling in apoptosis resistance and its role in cadmium-induced carcinogenesis.
    Son YO, Pratheeshkumar P, Roy RV, Hitron JA, Wang L, Zhang Z, Shi X.
    J Biol Chem; 2014 Oct 10; 289(41):28660-75. PubMed ID: 25157103
    [Abstract] [Full Text] [Related]

  • 7. Molecular changes during arsenic-induced cell transformation.
    Li G, Lee LS, Li M, Tsao SW, Chiu JF.
    J Cell Physiol; 2011 Dec 10; 226(12):3225-32. PubMed ID: 21344382
    [Abstract] [Full Text] [Related]

  • 8. Involvement of HIF-2α-mediated inflammation in arsenite-induced transformation of human bronchial epithelial cells.
    Xu Y, Zhao Y, Xu W, Luo F, Wang B, Li Y, Pang Y, Liu Q.
    Toxicol Appl Pharmacol; 2013 Oct 15; 272(2):542-50. PubMed ID: 23811328
    [Abstract] [Full Text] [Related]

  • 9. N6-methyladenosine mediates the cellular proliferation and apoptosis via microRNAs in arsenite-transformed cells.
    Gu S, Sun D, Dai H, Zhang Z.
    Toxicol Lett; 2018 Aug 15; 292():1-11. PubMed ID: 29680375
    [Abstract] [Full Text] [Related]

  • 10. Constitutive Activation of NAD-Dependent Sirtuin 3 Plays an Important Role in Tumorigenesis of Chromium(VI)-Transformed Cells.
    Clementino M, Kim D, Zhang Z.
    Toxicol Sci; 2019 May 01; 169(1):224-234. PubMed ID: 30715550
    [Abstract] [Full Text] [Related]

  • 11. Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells.
    Yang SP, Yang XZ, Cao GP.
    Mol Med Rep; 2015 Jul 01; 12(1):1145-50. PubMed ID: 25776802
    [Abstract] [Full Text] [Related]

  • 12. Sodium arsenite induced reactive oxygen species generation, nuclear factor (erythroid-2 related) factor 2 activation, heme oxygenase-1 expression, and glutathione elevation in Chang human hepatocytes.
    Li B, Li X, Zhu B, Zhang X, Wang Y, Xu Y, Wang H, Hou Y, Zheng Q, Sun G.
    Environ Toxicol; 2013 Jul 01; 28(7):401-10. PubMed ID: 21809430
    [Abstract] [Full Text] [Related]

  • 13. 2,3,5,6-Tetramethylpyrazine (TMP) down-regulated arsenic-induced heme oxygenase-1 and ARS2 expression by inhibiting Nrf2, NF-κB, AP-1 and MAPK pathways in human proximal tubular cells.
    Gong X, Ivanov VN, Hei TK.
    Arch Toxicol; 2016 Sep 01; 90(9):2187-2200. PubMed ID: 26404762
    [Abstract] [Full Text] [Related]

  • 14. Sustained high expression of NRF2 and its target genes induces dysregulation of cellular proliferation and apoptosis is associated with arsenite-induced malignant transformation of human bronchial epithelial cells.
    Kong Q, Deng H, Li C, Wang X, Shimoda Y, Tao S, Kato K, Zhang J, Yamanaka K, An Y.
    Sci Total Environ; 2021 Feb 20; 756():143840. PubMed ID: 33261869
    [Abstract] [Full Text] [Related]

  • 15. Hesperetin protects against H2O2-triggered oxidative damage via upregulation of the Keap1-Nrf2/HO-1 signal pathway in ARPE-19 cells.
    Zhu C, Dong Y, Liu H, Ren H, Cui Z.
    Biomed Pharmacother; 2017 Apr 20; 88():124-133. PubMed ID: 28103505
    [Abstract] [Full Text] [Related]

  • 16. PM2.5 induces Nrf2-mediated defense mechanisms against oxidative stress by activating PIK3/AKT signaling pathway in human lung alveolar epithelial A549 cells.
    Deng X, Rui W, Zhang F, Ding W.
    Cell Biol Toxicol; 2013 Jun 20; 29(3):143-57. PubMed ID: 23525690
    [Abstract] [Full Text] [Related]

  • 17. Luteolin inhibits Cr(VI)-induced malignant cell transformation of human lung epithelial cells by targeting ROS mediated multiple cell signaling pathways.
    Pratheeshkumar P, Son YO, Divya SP, Roy RV, Hitron JA, Wang L, Kim D, Dai J, Asha P, Zhang Z, Wang Y, Shi X.
    Toxicol Appl Pharmacol; 2014 Dec 01; 281(2):230-41. PubMed ID: 25448439
    [Abstract] [Full Text] [Related]

  • 18. Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling.
    Lee HH, Park SA, Almazari I, Kim EH, Na HK, Surh YJ.
    Arch Biochem Biophys; 2010 Sep 01; 501(1):142-50. PubMed ID: 20558128
    [Abstract] [Full Text] [Related]

  • 19. Sodium arsenite induces cyclooxygenase-2 expression in human uroepithelial cells through MAPK pathway activation and reactive oxygen species induction.
    Wang H, Xi S, Xu Y, Wang F, Zheng Y, Li B, Li X, Zheng Q, Sun G.
    Toxicol In Vitro; 2013 Apr 01; 27(3):1043-8. PubMed ID: 23376440
    [Abstract] [Full Text] [Related]

  • 20. Exosomal miR-21 derived from arsenite-transformed human bronchial epithelial cells promotes cell proliferation associated with arsenite carcinogenesis.
    Xu Y, Luo F, Liu Y, Shi L, Lu X, Xu W, Liu Q.
    Arch Toxicol; 2015 Jul 01; 89(7):1071-82. PubMed ID: 24912785
    [Abstract] [Full Text] [Related]


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