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Journal Abstract Search

296 related items for PubMed ID: 26439302

  • 1. The PZP Domain of AF10 Senses Unmodified H3K27 to Regulate DOT1L-Mediated Methylation of H3K79.
    Chen S, Yang Z, Wilkinson AW, Deshpande AJ, Sidoli S, Krajewski K, Strahl BD, Garcia BA, Armstrong SA, Patel DJ, Gozani O.
    Mol Cell; 2015 Oct 15; 60(2):319-27. PubMed ID: 26439302
    [Abstract] [Full Text] [Related]

  • 2. AF10 (MLLT10) prevents somatic cell reprogramming through regulation of DOT1L-mediated H3K79 methylation.
    Uğurlu-Çimen D, Odluyurt D, Sevinç K, Özkan-Küçük NE, Özçimen B, Demirtaş D, Enüstün E, Aztekin C, Philpott M, Oppermann U, Özlü N, Önder TT.
    Epigenetics Chromatin; 2021 Jul 02; 14(1):32. PubMed ID: 34215314
    [Abstract] [Full Text] [Related]

  • 3. DOT1L interaction partner AF10 controls patterning of H3K79 methylation and RNA polymerase II to maintain cell identity.
    Wille CK, Neumann EN, Deshpande AJ, Sridharan R.
    Stem Cell Reports; 2023 Dec 12; 18(12):2451-2463. PubMed ID: 37995701
    [Abstract] [Full Text] [Related]

  • 4. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells.
    Steger DJ, Lefterova MI, Ying L, Stonestrom AJ, Schupp M, Zhuo D, Vakoc AL, Kim JE, Chen J, Lazar MA, Blobel GA, Vakoc CR.
    Mol Cell Biol; 2008 Apr 12; 28(8):2825-39. PubMed ID: 18285465
    [Abstract] [Full Text] [Related]

  • 5. Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation.
    Kim W, Kim R, Park G, Park JW, Kim JE.
    J Biol Chem; 2012 Feb 17; 287(8):5588-99. PubMed ID: 22190683
    [Abstract] [Full Text] [Related]

  • 6. Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias.
    Lin YH, Kakadia PM, Chen Y, Li YQ, Deshpande AJ, Buske C, Zhang KL, Zhang Y, Xu GL, Bohlander SK.
    Blood; 2009 Jul 16; 114(3):651-8. PubMed ID: 19443658
    [Abstract] [Full Text] [Related]

  • 7. AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation.
    Li Y, Wen H, Xi Y, Tanaka K, Wang H, Peng D, Ren Y, Jin Q, Dent SY, Li W, Li H, Shi X.
    Cell; 2014 Oct 23; 159(3):558-71. PubMed ID: 25417107
    [Abstract] [Full Text] [Related]

  • 8. The histone methyltransferase Dot1/DOT1L as a critical regulator of the cell cycle.
    Kim W, Choi M, Kim JE.
    Cell Cycle; 2014 Oct 23; 13(5):726-38. PubMed ID: 24526115
    [Abstract] [Full Text] [Related]

  • 9. A higher-order configuration of the heterodimeric DOT1L-AF10 coiled-coil domains potentiates their leukemogenenic activity.
    Song X, Yang L, Wang M, Gu Y, Ye B, Fan Z, Xu RM, Yang N.
    Proc Natl Acad Sci U S A; 2019 Oct 01; 116(40):19917-19923. PubMed ID: 31527241
    [Abstract] [Full Text] [Related]

  • 10. DOT1L-mediated H3K79 methylation in chromatin is dispensable for Wnt pathway-specific and other intestinal epithelial functions.
    Ho LL, Sinha A, Verzi M, Bernt KM, Armstrong SA, Shivdasani RA.
    Mol Cell Biol; 2013 May 01; 33(9):1735-45. PubMed ID: 23428873
    [Abstract] [Full Text] [Related]

  • 11. The histone H3K79 methyltransferase Dot1L is essential for mammalian development and heterochromatin structure.
    Jones B, Su H, Bhat A, Lei H, Bajko J, Hevi S, Baltus GA, Kadam S, Zhai H, Valdez R, Gonzalo S, Zhang Y, Li E, Chen T.
    PLoS Genet; 2008 Sep 12; 4(9):e1000190. PubMed ID: 18787701
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  • 15. Bat3 facilitates H3K79 dimethylation by DOT1L and promotes DNA damage-induced 53BP1 foci at G1/G2 cell-cycle phases.
    Wakeman TP, Wang Q, Feng J, Wang XF.
    EMBO J; 2012 May 02; 31(9):2169-81. PubMed ID: 22373577
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  • 17. Regulation of the DNA damage response and gene expression by the Dot1L histone methyltransferase and the 53Bp1 tumour suppressor.
    FitzGerald J, Moureau S, Drogaris P, O'Connell E, Abshiru N, Verreault A, Thibault P, Grenon M, Lowndes NF.
    PLoS One; 2011 Feb 24; 6(2):e14714. PubMed ID: 21383990
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  • 18. Dot1L mediated histone H3 lysine79 methylation is essential to meiosis progression in mouse oocytes.
    Wang X, Gao W, Ma X, Wang X, Song C, Huang X, Liu H.
    Neuro Endocrinol Lett; 2014 Feb 24; 35(6):523-30. PubMed ID: 25433842
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  • 19. A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L.
    Anglin JL, Song Y.
    J Med Chem; 2013 Nov 27; 56(22):8972-83. PubMed ID: 23879463
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