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139 related items for PubMed ID: 26441251

  • 1. Use of physiologically based kinetic (PBK) modeling to study interindividual human variation and species differences in plasma concentrations of quercetin and its metabolites.
    Boonpawa R, Moradi N, Spenkelink A, Rietjens IM, Punt A.
    Biochem Pharmacol; 2015 Dec 15; 98(4):690-702. PubMed ID: 26441251
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  • 2. A physiologically based kinetic (PBK) model describing plasma concentrations of quercetin and its metabolites in rats.
    Boonpawa R, Spenkelink A, Rietjens IM, Punt A.
    Biochem Pharmacol; 2014 May 15; 89(2):287-99. PubMed ID: 24561179
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  • 3. Plasma metabolites of dietary flavonoids after combination meal consumption with onion and tofu in humans.
    Nakamura T, Murota K, Kumamoto S, Misumi K, Bando N, Ikushiro S, Takahashi N, Sekido K, Kato Y, Terao J.
    Mol Nutr Food Res; 2014 Feb 15; 58(2):310-7. PubMed ID: 24039174
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  • 4. UHPLC-(ESI)QTOF MS/MS profiling of quercetin metabolites in human plasma postconsumption of applesauce enriched with apple peel and onion.
    Lee J, Ebeler SE, Zweigenbaum JA, Mitchell AE.
    J Agric Food Chem; 2012 Aug 29; 60(34):8510-20. PubMed ID: 22867437
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  • 6. Human metabolism of dietary flavonoids: identification of plasma metabolites of quercetin.
    Day AJ, Mellon F, Barron D, Sarrazin G, Morgan MR, Williamson G.
    Free Radic Res; 2001 Dec 29; 35(6):941-52. PubMed ID: 11811545
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  • 7. Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose-response curves for developmental toxicity of phenol in rat and human.
    Strikwold M, Spenkelink B, Woutersen RA, Rietjens IM, Punt A.
    Arch Toxicol; 2013 Sep 29; 87(9):1709-23. PubMed ID: 23943240
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  • 10. Development of a Combined In Vitro Physiologically Based Kinetic (PBK) and Monte Carlo Modelling Approach to Predict Interindividual Human Variation in Phenol-Induced Developmental Toxicity.
    Strikwold M, Spenkelink B, Woutersen RA, Rietjens IMCM, Punt A.
    Toxicol Sci; 2017 Jun 01; 157(2):365-376. PubMed ID: 28498972
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  • 11. Flavonoid conjugates interact with organic anion transporters (OATs) and attenuate cytotoxicity of adefovir mediated by organic anion transporter 1 (OAT1/SLC22A6).
    Wong CC, Botting NP, Orfila C, Al-Maharik N, Williamson G.
    Biochem Pharmacol; 2011 Apr 01; 81(7):942-9. PubMed ID: 21244849
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  • 12. Intestinal disposition of quercetin and its phase-II metabolites after oral administration in healthy volunteers.
    Chalet C, Rubbens J, Tack J, Duchateau GS, Augustijns P.
    J Pharm Pharmacol; 2018 Aug 01; 70(8):1002-1008. PubMed ID: 29761870
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  • 16. Physiologically based kinetic modeling of hesperidin metabolism and its use to predict in vivo effective doses in humans.
    Boonpawa R, Spenkelink A, Punt A, Rietjens IMCM.
    Mol Nutr Food Res; 2017 Aug 01; 61(8):. PubMed ID: 28218440
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  • 17. Co-administration of quercetin and catechin in rats alters their absorption but not their metabolism.
    Silberberg M, Morand C, Manach C, Scalbert A, Remesy C.
    Life Sci; 2005 Nov 04; 77(25):3156-67. PubMed ID: 15979103
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  • 18. Evaluation of Interindividual Human Variation in Bioactivation and DNA Adduct Formation of Estragole in Liver Predicted by Physiologically Based Kinetic/Dynamic and Monte Carlo Modeling.
    Punt A, Paini A, Spenkelink A, Scholz G, Schilter B, van Bladeren PJ, Rietjens IM.
    Chem Res Toxicol; 2016 Apr 18; 29(4):659-68. PubMed ID: 26952143
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  • 19. Conjugated metabolites represent the major circulating forms of Abelmoschus manihot in vivo and show an altered pharmacokinetic profile in renal pathology.
    Guo J, Du L, Shang E, Li T, Liu Y, Qian D, Tang Y, Duan J.
    Pharm Biol; 2016 Apr 18; 54(4):595-603. PubMed ID: 26186460
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  • 20. Predicting points of departure for risk assessment based on in vitro cytotoxicity data and physiologically based kinetic (PBK) modeling: The case of kidney toxicity induced by aristolochic acid I.
    Abdullah R, Alhusainy W, Woutersen J, Rietjens IM, Punt A.
    Food Chem Toxicol; 2016 Jun 18; 92():104-16. PubMed ID: 27016491
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