These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Journal Abstract Search

264 related items for PubMed ID: 26453300

  • 1. GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site.
    Lu S, Banerjee A, Jang H, Zhang J, Gaponenko V, Nussinov R.
    J Biol Chem; 2015 Nov 27; 290(48):28887-900. PubMed ID: 26453300
    [Abstract] [Full Text] [Related]

  • 2. The higher level of complexity of K-Ras4B activation at the membrane.
    Jang H, Banerjee A, Chavan TS, Lu S, Zhang J, Gaponenko V, Nussinov R.
    FASEB J; 2016 Apr 27; 30(4):1643-55. PubMed ID: 26718888
    [Abstract] [Full Text] [Related]

  • 3. The Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B.
    Lu S, Jang H, Nussinov R, Zhang J.
    Sci Rep; 2016 Feb 23; 6():21949. PubMed ID: 26902995
    [Abstract] [Full Text] [Related]

  • 4. Conformational Dynamics Allows Sampling of an "Active-like" State by Oncogenic K-Ras-GDP.
    Grudzien P, Jang H, Leschinsky N, Nussinov R, Gaponenko V.
    J Mol Biol; 2022 Sep 15; 434(17):167695. PubMed ID: 35752212
    [Abstract] [Full Text] [Related]

  • 5. Markov State Models and Molecular Dynamics Simulations Reveal the Conformational Transition of the Intrinsically Disordered Hypervariable Region of K-Ras4B to the Ordered Conformation.
    Zhang H, Ni D, Fan J, Li M, Zhang J, Hua C, Nussinov R, Lu S.
    J Chem Inf Model; 2022 Sep 12; 62(17):4222-4231. PubMed ID: 35994329
    [Abstract] [Full Text] [Related]

  • 6. High-Affinity Interaction of the K-Ras4B Hypervariable Region with the Ras Active Site.
    Chavan TS, Jang H, Khavrutskii L, Abraham SJ, Banerjee A, Freed BC, Johannessen L, Tarasov SG, Gaponenko V, Nussinov R, Tarasova NI.
    Biophys J; 2015 Dec 15; 109(12):2602-2613. PubMed ID: 26682817
    [Abstract] [Full Text] [Related]

  • 7. Mechanisms of membrane binding of small GTPase K-Ras4B farnesylated hypervariable region.
    Jang H, Abraham SJ, Chavan TS, Hitchinson B, Khavrutskii L, Tarasova NI, Nussinov R, Gaponenko V.
    J Biol Chem; 2015 Apr 10; 290(15):9465-77. PubMed ID: 25713064
    [Abstract] [Full Text] [Related]

  • 8. Oncogenic and RASopathy-associated K-RAS mutations relieve membrane-dependent occlusion of the effector-binding site.
    Mazhab-Jafari MT, Marshall CB, Smith MJ, Gasmi-Seabrook GM, Stathopulos PB, Inagaki F, Kay LE, Neel BG, Ikura M.
    Proc Natl Acad Sci U S A; 2015 May 26; 112(21):6625-30. PubMed ID: 25941399
    [Abstract] [Full Text] [Related]

  • 9. The disordered hypervariable region and the folded catalytic domain of oncogenic K-Ras4B partner in phospholipid binding.
    Banerjee A, Jang H, Nussinov R, Gaponenko V.
    Curr Opin Struct Biol; 2016 Feb 26; 36():10-7. PubMed ID: 26709496
    [Abstract] [Full Text] [Related]

  • 10. Nucleotide-Specific Autoinhibition of Full-Length K-Ras4B Identified by Extensive Conformational Sampling.
    Dudas B, Merzel F, Jang H, Nussinov R, Perahia D, Balog E.
    Front Mol Biosci; 2020 Feb 26; 7():145. PubMed ID: 32754617
    [Abstract] [Full Text] [Related]

  • 11. Flexible-body motions of calmodulin and the farnesylated hypervariable region yield a high-affinity interaction enabling K-Ras4B membrane extraction.
    Jang H, Banerjee A, Chavan T, Gaponenko V, Nussinov R.
    J Biol Chem; 2017 Jul 28; 292(30):12544-12559. PubMed ID: 28623230
    [Abstract] [Full Text] [Related]

  • 12. Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling.
    Muratcioglu S, Aydin C, Odabasi E, Ozdemir ES, Firat-Karalar EN, Jang H, Tsai CJ, Nussinov R, Kavakli IH, Gursoy A, Keskin O.
    J Mol Biol; 2020 Feb 14; 432(4):1199-1215. PubMed ID: 31931009
    [Abstract] [Full Text] [Related]

  • 13.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 14.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 15.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 16. Electrostatic control of GTP and GDP binding in the oncoprotein p21ras.
    Muegge I, Schweins T, Langen R, Warshel A.
    Structure; 1996 Apr 15; 4(4):475-89. PubMed ID: 8740369
    [Abstract] [Full Text] [Related]

  • 17.
    ; . PubMed ID:
    [No Abstract] [Full Text] [Related]

  • 18. Comparison of ras-p21 bound to GDP and GTP: differences in protein and ligand dynamics.
    Mello LV, van Aalten DM, Findlay JB.
    Protein Eng; 1997 Apr 15; 10(4):381-7. PubMed ID: 9194162
    [Abstract] [Full Text] [Related]

  • 19. Guanine-nucleotide binding activity, interaction with GTPase-activating protein and solution conformation of the human c-Ha-Ras protein catalytic domain are retained upon deletion of C-terminal 18 amino acid residues.
    Fujita-Yoshigaki J, Ito Y, Yamasaki K, Muto Y, Miyazawa T, Nishimura S, Yokoyama S.
    J Protein Chem; 1992 Dec 15; 11(6):731-9. PubMed ID: 1466766
    [Abstract] [Full Text] [Related]

  • 20. The hypervariable region of K-Ras4B is responsible for its specific interactions with calmodulin.
    Abraham SJ, Nolet RP, Calvert RJ, Anderson LM, Gaponenko V.
    Biochemistry; 2009 Aug 18; 48(32):7575-83. PubMed ID: 19583261
    [Abstract] [Full Text] [Related]

    Page: [Next] [New Search]
    of 14.