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Journal Abstract Search

722 related items for PubMed ID: 26481827

  • 1. Emerging Approaches to GPCR Ligand Screening for Drug Discovery.
    Kumari P, Ghosh E, Shukla AK.
    Trends Mol Med; 2015 Nov; 21(11):687-701. PubMed ID: 26481827
    [Abstract] [Full Text] [Related]

  • 2. Fragment-based lead discovery on G-protein-coupled receptors.
    Visegrády A, Keserű GM.
    Expert Opin Drug Discov; 2013 Jul; 8(7):811-20. PubMed ID: 23621346
    [Abstract] [Full Text] [Related]

  • 3. The identification of high-affinity G protein-coupled receptor ligands from large combinatorial libraries using multicolor quantum dot-labeled cell-based screening.
    Fu J, Lee T, Qi X.
    Future Med Chem; 2014 May; 6(7):809-23. PubMed ID: 24941874
    [Abstract] [Full Text] [Related]

  • 4. GPCR profiling: from hits to leads and from genotype to phenotype.
    Cvijic ME, Sum CS, Alt A, Zhang L.
    Drug Discov Today Technol; 2015 Nov; 18():30-7. PubMed ID: 26723890
    [Abstract] [Full Text] [Related]

  • 5. X-ray structure breakthroughs in the GPCR transmembrane region.
    Topiol S, Sabio M.
    Biochem Pharmacol; 2009 Jul 01; 78(1):11-20. PubMed ID: 19447219
    [Abstract] [Full Text] [Related]

  • 6. Surface plasmon resonance analysis of seven-transmembrane receptors.
    Aristotelous T, Hopkins AL, Navratilova I.
    Methods Enzymol; 2015 Jul 01; 556():499-525. PubMed ID: 25857797
    [Abstract] [Full Text] [Related]

  • 7. Modeling and Deorphanization of Orphan GPCRs.
    Diaz C, Angelloz-Nicoud P, Pihan E.
    Methods Mol Biol; 2018 Jul 01; 1705():413-429. PubMed ID: 29188576
    [Abstract] [Full Text] [Related]

  • 8. GPCR structures in drug design, emerging opportunities with new structures.
    Tautermann CS.
    Bioorg Med Chem Lett; 2014 Sep 01; 24(17):4073-9. PubMed ID: 25086683
    [Abstract] [Full Text] [Related]

  • 9. Ligand Discovery for a Peptide-Binding GPCR by Structure-Based Screening of Fragment- and Lead-Like Chemical Libraries.
    Ranganathan A, Heine P, Rudling A, Plückthun A, Kummer L, Carlsson J.
    ACS Chem Biol; 2017 Mar 17; 12(3):735-745. PubMed ID: 28032980
    [Abstract] [Full Text] [Related]

  • 10. Structural insights into ligand recognition and selectivity for classes A, B, and C GPCRs.
    Lee SM, Booe JM, Pioszak AA.
    Eur J Pharmacol; 2015 Sep 15; 763(Pt B):196-205. PubMed ID: 25981303
    [Abstract] [Full Text] [Related]

  • 11. Allosteric inhibition of g-protein coupled receptor oligomerization: strategies and challenges for drug development.
    Hurevich M, Talhami A, Shalev DE, Gilon C.
    Curr Top Med Chem; 2014 Sep 15; 14(15):1842-63. PubMed ID: 25175995
    [Abstract] [Full Text] [Related]

  • 12. Applications of machine learning in GPCR bioactive ligand discovery.
    Jabeen A, Ranganathan S.
    Curr Opin Struct Biol; 2019 Apr 15; 55():66-76. PubMed ID: 31005679
    [Abstract] [Full Text] [Related]

  • 13. Small Molecule Allosteric Modulators of G-Protein-Coupled Receptors: Drug-Target Interactions.
    Lu S, Zhang J.
    J Med Chem; 2019 Jan 10; 62(1):24-45. PubMed ID: 29457894
    [Abstract] [Full Text] [Related]

  • 14. Discovery of GPCR Ligands by Molecular Docking Screening: Novel Opportunities Provided by Crystal Structures.
    Rodríguez D, Ranganathan A, Carlsson J.
    Curr Top Med Chem; 2015 Jan 10; 15(24):2484-503. PubMed ID: 26126906
    [Abstract] [Full Text] [Related]

  • 15. Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts.
    Wold EA, Chen J, Cunningham KA, Zhou J.
    J Med Chem; 2019 Jan 10; 62(1):88-127. PubMed ID: 30106578
    [Abstract] [Full Text] [Related]

  • 16. Ligand and decoy sets for docking to G protein-coupled receptors.
    Gatica EA, Cavasotto CN.
    J Chem Inf Model; 2012 Jan 23; 52(1):1-6. PubMed ID: 22168315
    [Abstract] [Full Text] [Related]

  • 17. G-protein-coupled receptor-focused drug discovery using a target class platform approach.
    Heilker R, Wolff M, Tautermann CS, Bieler M.
    Drug Discov Today; 2009 Mar 23; 14(5-6):231-40. PubMed ID: 19121411
    [Abstract] [Full Text] [Related]

  • 18. Emerging structural insights into biased GPCR signaling.
    Shukla AK, Singh G, Ghosh E.
    Trends Biochem Sci; 2014 Dec 23; 39(12):594-602. PubMed ID: 25458114
    [Abstract] [Full Text] [Related]

  • 19. From purified GPCRs to drug discovery: the promise of protein-based methodologies.
    Alkhalfioui F, Magnin T, Wagner R.
    Curr Opin Pharmacol; 2009 Oct 23; 9(5):629-35. PubMed ID: 19443270
    [Abstract] [Full Text] [Related]

  • 20. How Ligands Illuminate GPCR Molecular Pharmacology.
    Wacker D, Stevens RC, Roth BL.
    Cell; 2017 Jul 27; 170(3):414-427. PubMed ID: 28753422
    [Abstract] [Full Text] [Related]

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