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104 related items for PubMed ID: 2649467

  • 1. Assessment of the repair and damage of DNA induced by parent and reduced RSU-1069, a 2-nitroimidazole-aziridine.
    O'Neill P, Cunniffe SM.
    Int J Radiat Oncol Biol Phys; 1989 Apr; 16(4):963-6. PubMed ID: 2649467
    [Abstract] [Full Text] [Related]

  • 2. Enhancement of DNA damage in mammalian cells upon bioreduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131.
    Jenner TJ, Sapora O, O'Neill P, Fielden EM.
    Biochem Pharmacol; 1988 Oct 15; 37(20):3837-42. PubMed ID: 3190731
    [Abstract] [Full Text] [Related]

  • 3. The repair of DNA damage induced in V79 mammalian cells by the nitroimidazole-aziridine, RSU-1069. Implications for radiosensitization.
    Jenner TJ, O'Neill P, Crump PW, Fielden EM, Sapora O, Santodonato L.
    Biochem Pharmacol; 1991 Oct 09; 42(9):1705-10. PubMed ID: 1930296
    [Abstract] [Full Text] [Related]

  • 4. Comparative DNA damage and repair induced by misonidazole, CB 1954 and RSU 1069.
    Dale LD, Widdick DA, Edwards DI, Biol GI.
    Int J Radiat Oncol Biol Phys; 1989 Apr 09; 16(4):995-9. PubMed ID: 2649469
    [Abstract] [Full Text] [Related]

  • 5. The phosphate-group of DNA as a potential target for RSU-1069, a nitroimidazole-aziridine radiosensitizer.
    Silver AR, O'Neill P, Jenkins TC, McNeil SS.
    Int J Radiat Oncol Biol Phys; 1986 Jul 09; 12(7):1203-6. PubMed ID: 3755715
    [Abstract] [Full Text] [Related]

  • 6. Induction of DNA strand breaks by RSU-1069, a nitroimidazole-aziridine radiosensitizer. Role of binding of both unreduced and radiation-reduced forms to DNA, in vitro.
    Silver AR, O'Neill P, Jenkins TC.
    Biochem Pharmacol; 1985 Oct 01; 34(19):3537-42. PubMed ID: 3902026
    [Abstract] [Full Text] [Related]

  • 7. Studies on the toxicity of RSU-1069.
    Whitmore GF, Gulyas S.
    Int J Radiat Oncol Biol Phys; 1986 Jul 01; 12(7):1219-22. PubMed ID: 3755716
    [Abstract] [Full Text] [Related]

  • 8. Induction of DNA crosslinks in vitro upon reduction of the nitroimidazole-aziridines RSU-1069 and RSU-1131.
    O'Neill P, McNeil SS, Jenkins TC.
    Biochem Pharmacol; 1987 Jun 01; 36(11):1787-92. PubMed ID: 3579973
    [Abstract] [Full Text] [Related]

  • 9. Mechanism of action of some bioreducible 2-nitroimidazoles: comparison of in vitro cytotoxicity and ability to induce DNA strand breakage.
    O'Neill P, Jenkins TC, Stratford IJ, Silver AR, Ahmed I, McNeil SS, Fielden EM, Adams GE.
    Anticancer Drug Des; 1987 Apr 01; 1(4):271-80. PubMed ID: 3450299
    [Abstract] [Full Text] [Related]

  • 10. Comparative DNA damage induced by nitroimidazole-aziridine drugs: 1. Effects of methyl substitution on drug action.
    Dale LD, Tocher JH, Edwards DI.
    Anticancer Drug Des; 1988 Dec 01; 3(3):169-75. PubMed ID: 3207464
    [Abstract] [Full Text] [Related]

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  • 12. Studies with bifunctional bioreductive drugs. II. Cytotoxicity assayed with A-549 lung carcinoma cells of human origin.
    Roizin-Towle L, Pirro JP, Hall EJ.
    Radiat Res; 1990 Oct 01; 124(1 Suppl):S50-5. PubMed ID: 2236511
    [Abstract] [Full Text] [Related]

  • 13. Variation of the radiosensitizing efficiency of RSU-1069 with pre-irradiation contact times: a rapid mix study.
    Austen KR, Jenner TJ, O'Neill P, Fielden EM.
    Int J Radiat Biol Relat Stud Phys Chem Med; 1987 Aug 01; 52(2):281-8. PubMed ID: 3497125
    [Abstract] [Full Text] [Related]

  • 14. The differential cytotoxicity of RSU 1069: cell survival studies indicating interaction with DNA as a possible mode of action.
    Stratford IJ, Walling JM, Silver AR.
    Br J Cancer; 1986 Mar 01; 53(3):339-44. PubMed ID: 3754453
    [Abstract] [Full Text] [Related]

  • 15. Induction of DNA strand breaks by reduced nitroimidazoles. Implications for DNA base damage.
    Silver AR, McNeil SS, O'Neill P, Jenkins TC, Ahmed I.
    Biochem Pharmacol; 1986 Nov 15; 35(22):3923-8. PubMed ID: 3778516
    [Abstract] [Full Text] [Related]

  • 16. Cytotoxicity of RSU 1069 in spheroids and murine tumors.
    Olive PL, Durand RE, Chaplin DJ.
    Int J Radiat Oncol Biol Phys; 1987 Sep 15; 13(9):1361-6. PubMed ID: 3624045
    [Abstract] [Full Text] [Related]

  • 17. Inactivation and repair of double-stranded DNA damaged by the aziridinyl nitroimidazole RSU 1069.
    Lafleur MV, Westmijze EJ, Visser OJ, Wagenaar N, Soetekouw R, Loman H, Retel J.
    Chem Biol Interact; 1992 Mar 15; 82(1):55-71. PubMed ID: 1532139
    [Abstract] [Full Text] [Related]

  • 18. Analogues of RSU-1069: radiosensitization and toxicity in vitro and in vivo.
    Ahmed I, Jenkins TC, Walling JM, Stratford IJ, Sheldon PW, Adams GE, Fielden EM.
    Int J Radiat Oncol Biol Phys; 1986 Jul 15; 12(7):1079-81. PubMed ID: 3755711
    [Abstract] [Full Text] [Related]

  • 19. Dual-function radiation sensitizers and bioreductive drugs: factors affecting cellular uptake and sensitizing efficiency in analogues of RSU 1069.
    Walling J, Stratford IJ, Adams GE, Stephens MA.
    Int J Radiat Biol Relat Stud Phys Chem Med; 1988 Apr 15; 53(4):641-9. PubMed ID: 3258298
    [Abstract] [Full Text] [Related]

  • 20. Studies on the mechanisms of the radiosensitizing and cytotoxic properties of RSU-1069 and its analogues.
    Walling JM, Stratford IJ, Adams GE, Silver AR, Ahmed I, Jenkins TC, Fielden EM.
    Int J Radiat Oncol Biol Phys; 1986 Jul 15; 12(7):1083-6. PubMed ID: 3755712
    [Abstract] [Full Text] [Related]

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