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488 related items for PubMed ID: 26496737

  • 1. RIP1K and RIP3K provoked by shikonin induce cell cycle arrest in the triple negative breast cancer cell line, MDA-MB-468: necroptosis as a desperate programmed suicide pathway.
    Shahsavari Z, Karami-Tehrani F, Salami S, Ghasemzadeh M.
    Tumour Biol; 2016 Apr; 37(4):4479-91. PubMed ID: 26496737
    [Abstract] [Full Text] [Related]

  • 2. Targeting Cell Necroptosis and Apoptosis Induced by Shikonin via Receptor Interacting Protein Kinases in Estrogen Receptor Positive Breast Cancer Cell Line, MCF-7.
    Shahsavari Z, Karami-Tehrani F, Salami S.
    Anticancer Agents Med Chem; 2018 Apr; 18(2):245-254. PubMed ID: 28933271
    [Abstract] [Full Text] [Related]

  • 3. Shikonin Induced Necroptosis via Reactive Oxygen Species in the T-47D Breast Cancer Cell Line.
    Shahsavari Z, Karami-Tehrani F, Salami S.
    Asian Pac J Cancer Prev; 2015 Apr; 16(16):7261-6. PubMed ID: 26514521
    [Abstract] [Full Text] [Related]

  • 4. Evaluation of RIP1K and RIP3K expressions in the malignant and benign breast tumors.
    Karami-Tehrani F, Malek AR, Shahsavari Z, Atri M.
    Tumour Biol; 2016 Jul; 37(7):8849-56. PubMed ID: 26749282
    [Abstract] [Full Text] [Related]

  • 5. Shikonin induces glioma cell necroptosis in vitro by ROS overproduction and promoting RIP1/RIP3 necrosome formation.
    Lu B, Gong X, Wang ZQ, Ding Y, Wang C, Luo TF, Piao MH, Meng FK, Chi GF, Luo YN, Ge PF.
    Acta Pharmacol Sin; 2017 Nov; 38(11):1543-1553. PubMed ID: 28816233
    [Abstract] [Full Text] [Related]

  • 6. Pyoluteorin induces cell cycle arrest and apoptosis in human triple-negative breast cancer cells MDA-MB-231.
    Ding T, Yang LJ, Zhang WD, Shen YH.
    J Pharm Pharmacol; 2020 Jul; 72(7):969-978. PubMed ID: 32246778
    [Abstract] [Full Text] [Related]

  • 7. Shikonin induces apoptosis of HaCaT cells via the mitochondrial, Erk and Akt pathways.
    Jing H, Sun W, Fan J, Zhang Y, Yang J, Jia J, Li J, Guo J, Luo S, Zheng Y.
    Mol Med Rep; 2016 Apr; 13(4):3009-16. PubMed ID: 26935874
    [Abstract] [Full Text] [Related]

  • 8. Shikonin kills glioma cells through necroptosis mediated by RIP-1.
    Huang C, Luo Y, Zhao J, Yang F, Zhao H, Fan W, Ge P.
    PLoS One; 2013 Apr; 8(6):e66326. PubMed ID: 23840441
    [Abstract] [Full Text] [Related]

  • 9. Dillenia suffruticosa dichloromethane root extract induced apoptosis towards MDA-MB-231 triple-negative breast cancer cells.
    Foo JB, Saiful Yazan L, Tor YS, Wibowo A, Ismail N, Armania N, Cheah YK, Abdullah R.
    J Ethnopharmacol; 2016 Jul 01; 187():195-204. PubMed ID: 27131434
    [Abstract] [Full Text] [Related]

  • 10. The anti-tumor effect of shikonin on osteosarcoma by inducing RIP1 and RIP3 dependent necroptosis.
    Fu Z, Deng B, Liao Y, Shan L, Yin F, Wang Z, Zeng H, Zuo D, Hua Y, Cai Z.
    BMC Cancer; 2013 Dec 06; 13():580. PubMed ID: 24314238
    [Abstract] [Full Text] [Related]

  • 11. Shikonin-induced necroptosis is enhanced by the inhibition of autophagy in non-small cell lung cancer cells.
    Kim HJ, Hwang KE, Park DS, Oh SH, Jun HY, Yoon KH, Jeong ET, Kim HR, Kim YS.
    J Transl Med; 2017 May 31; 15(1):123. PubMed ID: 28569199
    [Abstract] [Full Text] [Related]

  • 12. Shikonin time-dependently induced necrosis or apoptosis in gastric cancer cells via generation of reactive oxygen species.
    Lee MJ, Kao SH, Hunag JE, Sheu GT, Yeh CW, Hseu YC, Wang CJ, Hsu LS.
    Chem Biol Interact; 2014 Mar 25; 211():44-53. PubMed ID: 24463199
    [Abstract] [Full Text] [Related]

  • 13. Ginsenoside Rk1 induces cell cycle arrest and apoptosis in MDA-MB-231 triple negative breast cancer cells.
    Hong Y, Fan D.
    Toxicology; 2019 Apr 15; 418():22-31. PubMed ID: 30797898
    [Abstract] [Full Text] [Related]

  • 14. ERK-modulated intrinsic signaling and G(2)/M phase arrest contribute to the induction of apoptotic death by allyl isothiocyanate in MDA-MB-468 human breast adenocarcinoma cells.
    Tsai SC, Huang WW, Huang WC, Lu CC, Chiang JH, Peng SF, Chung JG, Lin YH, Hsu YM, Amagaya S, Yang JS.
    Int J Oncol; 2012 Dec 15; 41(6):2065-72. PubMed ID: 23008020
    [Abstract] [Full Text] [Related]

  • 15. The molecular mechanisms and gene expression profiling for shikonin-induced apoptotic and necroptotic cell death in U937 cells.
    Piao JL, Cui ZG, Furusawa Y, Ahmed K, Rehman MU, Tabuchi Y, Kadowaki M, Kondo T.
    Chem Biol Interact; 2013 Sep 25; 205(2):119-27. PubMed ID: 23811387
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of ROS production, autophagy or apoptosis signaling reversed the anticancer properties of Antrodia salmonea in triple-negative breast cancer (MDA-MB-231) cells.
    Chang CT, Korivi M, Huang HC, Thiyagarajan V, Lin KY, Huang PJ, Liu JY, Hseu YC, Yang HL.
    Food Chem Toxicol; 2017 May 25; 103():1-17. PubMed ID: 28219700
    [Abstract] [Full Text] [Related]

  • 17. Gene Expression Alterations Associated with Oleuropein-Induced Antiproliferative Effects and S-Phase Cell Cycle Arrest in Triple-Negative Breast Cancer Cells.
    Messeha SS, Zarmouh NO, Asiri A, Soliman KFA.
    Nutrients; 2020 Dec 07; 12(12):. PubMed ID: 33297339
    [Abstract] [Full Text] [Related]

  • 18. Shikonin induces necroptosis by reactive oxygen species activation in nasopharyngeal carcinoma cell line CNE-2Z.
    Zhang Z, Zhang Z, Li Q, Jiao H, Chong D, Sun X, Zhang P, Huo Q, Liu H.
    J Bioenerg Biomembr; 2017 Jun 07; 49(3):265-272. PubMed ID: 28547157
    [Abstract] [Full Text] [Related]

  • 19. A new pyrrole based small molecule from Tinospora cordifolia induces apoptosis in MDA-MB-231 breast cancer cells via ROS mediated mitochondrial damage and restoration of p53 activity.
    Rashmi KC, Harsha Raj M, Paul M, Girish KS, Salimath BP, Aparna HS.
    Chem Biol Interact; 2019 Feb 01; 299():120-130. PubMed ID: 30543781
    [Abstract] [Full Text] [Related]

  • 20. Shikonin induces cell cycle arrest in human gastric cancer (AGS) by early growth response 1 (Egr1)-mediated p21 gene expression.
    Kim SJ, Kim JM, Shim SH, Chang HI.
    J Ethnopharmacol; 2014 Feb 12; 151(3):1064-1071. PubMed ID: 24384380
    [Abstract] [Full Text] [Related]

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