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307 related items for PubMed ID: 26503893

  • 1. PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase.
    Inoue M, Yoshimura M, Kobayashi M, Morinibu A, Itasaka S, Hiraoka M, Harada H.
    Sci Rep; 2015 Oct 27; 5():15666. PubMed ID: 26503893
    [Abstract] [Full Text] [Related]

  • 2. Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer.
    Klauck PJ, Bagby SM, Capasso A, Bradshaw-Pierce EL, Selby HM, Spreafico A, Tentler JJ, Tan AC, Kim J, Arcaroli JJ, Purkey A, Messersmith WA, Kuida K, Eckhardt SG, Pitts TM.
    BMC Cancer; 2018 Feb 05; 18(1):136. PubMed ID: 29402316
    [Abstract] [Full Text] [Related]

  • 3. TAK-960, a novel, orally available, selective inhibitor of polo-like kinase 1, shows broad-spectrum preclinical antitumor activity in multiple dosing regimens.
    Hikichi Y, Honda K, Hikami K, Miyashita H, Kaieda I, Murai S, Uchiyama N, Hasegawa M, Kawamoto T, Sato T, Ichikawa T, Cao S, Nie Z, Zhang L, Yang J, Kuida K, Kupperman E.
    Mol Cancer Ther; 2012 Mar 05; 11(3):700-9. PubMed ID: 22188812
    [Abstract] [Full Text] [Related]

  • 4. Inhibition of polo-like kinase 1 leads to the suppression of osteosarcoma cell growth in vitro and in vivo.
    Liu X, Choy E, Harmon D, Yang S, Yang C, Mankin H, Hornicek FJ, Duan Z.
    Anticancer Drugs; 2011 Jun 05; 22(5):444-53. PubMed ID: 21399492
    [Abstract] [Full Text] [Related]

  • 5. Polo-like kinase 1 inhibitor BI2536 causes mitotic catastrophe following activation of the spindle assembly checkpoint in non-small cell lung cancer cells.
    Choi M, Kim W, Cheon MG, Lee CW, Kim JE.
    Cancer Lett; 2015 Feb 28; 357(2):591-601. PubMed ID: 25524551
    [Abstract] [Full Text] [Related]

  • 6. PLK1 Inhibition Sensitizes Breast Cancer Cells to Radiation via Suppressing Autophagy.
    Wang B, Huang X, Liang H, Yang H, Guo Z, Ai M, Zhang J, Khan M, Tian Y, Sun Q, Mao Z, Zheng R, Yuan Y.
    Int J Radiat Oncol Biol Phys; 2021 Jul 15; 110(4):1234-1247. PubMed ID: 33621661
    [Abstract] [Full Text] [Related]

  • 7. Efficient inhibition of human colorectal carcinoma growth by RNA interference targeting polo-like kinase 1 in vitro and in vivo.
    Xu WJ, Zhang S, Yang Y, Zhang N, Wang W, Liu SY, Tian HW, Dai L, Xie Q, Zhao X, Wei YQ, Deng HX.
    Cancer Biother Radiopharm; 2011 Aug 15; 26(4):427-36. PubMed ID: 21797676
    [Abstract] [Full Text] [Related]

  • 8. Radiosensitization in esophageal squamous cell carcinoma: Effect of polo-like kinase 1 inhibition.
    Chen JL, Chen JP, Huang YS, Tsai YC, Tsai MH, Jaw FS, Cheng JC, Kuo SH, Shieh MJ.
    Strahlenther Onkol; 2016 Apr 15; 192(4):260-8. PubMed ID: 26952039
    [Abstract] [Full Text] [Related]

  • 9. Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo.
    Yuan J, Sanhaji M, Krämer A, Reindl W, Hofmann M, Kreis NN, Zimmer B, Berg T, Strebhardt K.
    Am J Pathol; 2011 Oct 15; 179(4):2091-9. PubMed ID: 21839059
    [Abstract] [Full Text] [Related]

  • 10. Targeting polo-like kinase 1 enhances radiation efficacy for head-and-neck squamous cell carcinoma.
    Gerster K, Shi W, Ng B, Yue S, Ito E, Waldron J, Gilbert R, Liu FF.
    Int J Radiat Oncol Biol Phys; 2010 May 01; 77(1):253-60. PubMed ID: 20394857
    [Abstract] [Full Text] [Related]

  • 11. Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.
    Harris PS, Venkataraman S, Alimova I, Birks DK, Donson AM, Knipstein J, Dubuc A, Taylor MD, Handler MH, Foreman NK, Vibhakar R.
    BMC Cancer; 2012 Mar 05; 12():80. PubMed ID: 22390279
    [Abstract] [Full Text] [Related]

  • 12. Small molecule inhibition of polo-like kinase 1 by volasertib (BI 6727) causes significant melanoma growth delay and regression in vivo.
    Cholewa BD, Ndiaye MA, Huang W, Liu X, Ahmad N.
    Cancer Lett; 2017 Jan 28; 385():179-187. PubMed ID: 27793694
    [Abstract] [Full Text] [Related]

  • 13. In vitro PLK1 inhibition by BI 2536 decreases proliferation and induces cell-cycle arrest in melanoma cells.
    de Oliveira JC, Brassesco MS, Pezuk JA, Morales AG, Valera ET, Montaldi AP, Sakamoto-Hojo ET, Scrideli CA, Tone LG.
    J Drugs Dermatol; 2012 May 28; 11(5):587-92. PubMed ID: 22527426
    [Abstract] [Full Text] [Related]

  • 14. Influence of chk1 and plk1 silencing on radiation- or cisplatin-induced cytotoxicity in human malignant cells.
    Gao Q, Huang X, Tang D, Cao Y, Chen G, Lu Y, Zhuang L, Wang S, Xu G, Zhou J, Ma D.
    Apoptosis; 2006 Oct 28; 11(10):1789-800. PubMed ID: 16927022
    [Abstract] [Full Text] [Related]

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  • 16. RO3280: A Novel PLK1 Inhibitor, Suppressed the Proliferation of MCF-7 Breast Cancer Cells Through the Induction of Cell Cycle Arrest at G2/M Point.
    Ergul M, Bakar-Ates F.
    Anticancer Agents Med Chem; 2019 Oct 28; 19(15):1846-1854. PubMed ID: 31244432
    [Abstract] [Full Text] [Related]

  • 17. Distinct concentration-dependent effects of the polo-like kinase 1-specific inhibitor GSK461364A, including differential effect on apoptosis.
    Gilmartin AG, Bleam MR, Richter MC, Erskine SG, Kruger RG, Madden L, Hassler DF, Smith GK, Gontarek RR, Courtney MP, Sutton D, Diamond MA, Jackson JR, Laquerre SG.
    Cancer Res; 2009 Sep 01; 69(17):6969-77. PubMed ID: 19690138
    [Abstract] [Full Text] [Related]

  • 18. Discovery of TAK-960: an orally available small molecule inhibitor of polo-like kinase 1 (PLK1).
    Nie Z, Feher V, Natala S, McBride C, Kiryanov A, Jones B, Lam B, Liu Y, Kaldor S, Stafford J, Hikami K, Uchiyama N, Kawamoto T, Hikichi Y, Matsumoto S, Amano N, Zhang L, Hosfield D, Skene R, Zou H, Cao X, Ichikawa T.
    Bioorg Med Chem Lett; 2013 Jun 15; 23(12):3662-6. PubMed ID: 23664874
    [Abstract] [Full Text] [Related]

  • 19. Polo-like kinase 1 inhibitors, mitotic stress and the tumor suppressor p53.
    Sanhaji M, Louwen F, Zimmer B, Kreis NN, Roth S, Yuan J.
    Cell Cycle; 2013 May 01; 12(9):1340-51. PubMed ID: 23574746
    [Abstract] [Full Text] [Related]

  • 20. Enhanced chemosensitivity to CPT-11 in colorectal carcinoma xenografts by small hairpin RNA interference targeting PLK1.
    Fan P, Zhang S, Tian H, Yan N, Dai L, Zhang X, Cheng L, Li C, Li Y, Chen X, Shi G, Yang Y, Wei Y, Deng H.
    Neoplasma; 2012 May 01; 59(6):676-84. PubMed ID: 22862168
    [Abstract] [Full Text] [Related]

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