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Journal Abstract Search

156 related items for PubMed ID: 26506423

  • 1. Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells.
    Wu S, Guo Z, Hopkins CD, Wei N, Chu E, Wipf P, Schmitz JC.
    Oncotarget; 2015 Dec 01; 6(38):40866-79. PubMed ID: 26506423
    [Abstract] [Full Text] [Related]

  • 2. YSL-12, a novel microtubule-destabilizing agent, exerts potent anti-tumor activity against colon cancer in vitro and in vivo.
    Cai D, Qiu Z, Yao W, Liu Y, Huang H, Liao S, Luo Q, Xie L, Lin Z.
    Cancer Chemother Pharmacol; 2016 Jun 01; 77(6):1217-29. PubMed ID: 27107592
    [Abstract] [Full Text] [Related]

  • 3. Identifying a resistance determinant for the antimitotic natural products disorazole C1 and A1.
    Lazo JS, Reese CE, Vogt A, Vollmer LL, Kitchens CA, Günther E, Graham TH, Hopkins CD, Wipf P.
    J Pharmacol Exp Ther; 2010 Mar 01; 332(3):906-11. PubMed ID: 20008956
    [Abstract] [Full Text] [Related]

  • 4. A novel synthetic compound exerts effective anti-tumour activity in vivo via the inhibition of tubulin polymerisation in A549 cells.
    Yan J, Pang Y, Sheng J, Wang Y, Chen J, Hu J, Huang L, Li X.
    Biochem Pharmacol; 2015 Sep 01; 97(1):51-61. PubMed ID: 26212540
    [Abstract] [Full Text] [Related]

  • 5. Microtubule binding and disruption and induction of premature senescence by disorazole C(1).
    Tierno MB, Kitchens CA, Petrik B, Graham TH, Wipf P, Xu FL, Saunders WS, Raccor BS, Balachandran R, Day BW, Stout JR, Walczak CE, Ducruet AP, Reese CE, Lazo JS.
    J Pharmacol Exp Ther; 2009 Mar 01; 328(3):715-22. PubMed ID: 19066338
    [Abstract] [Full Text] [Related]

  • 6. Leiodermatolide, a novel marine natural product, has potent cytotoxic and antimitotic activity against cancer cells, appears to affect microtubule dynamics, and exhibits antitumor activity.
    Guzmán EA, Xu Q, Pitts TP, Mitsuhashi KO, Baker C, Linley PA, Oestreicher J, Tendyke K, Winder PL, Suh EM, Wright AE.
    Int J Cancer; 2016 Nov 01; 139(9):2116-26. PubMed ID: 27376928
    [Abstract] [Full Text] [Related]

  • 7. Repurposing of phentolamine as a potential anticancer agent against human castration-resistant prostate cancer: A central role on microtubule stabilization and mitochondrial apoptosis pathway.
    Ho CH, Hsu JL, Liu SP, Hsu LC, Chang WL, Chao CC, Guh JH.
    Prostate; 2015 Sep 01; 75(13):1454-66. PubMed ID: 26180030
    [Abstract] [Full Text] [Related]

  • 8. Salvinal, a novel microtubule inhibitor isolated from Salvia miltiorrhizae Bunge (Danshen), with antimitotic activity in multidrug-sensitive and -resistant human tumor cells.
    Chang JY, Chang CY, Kuo CC, Chen LT, Wein YS, Kuo YH.
    Mol Pharmacol; 2004 Jan 01; 65(1):77-84. PubMed ID: 14722239
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.
    Wang F, Yang Z, Liu Y, Ma L, Wu Y, He L, Shao M, Yu K, Wu W, Pu Y, Nie C, Chen L.
    Bioorg Med Chem; 2015 Jul 01; 23(13):3337-50. PubMed ID: 25937236
    [Abstract] [Full Text] [Related]

  • 10. Development of Novel Bis(indolyl)-hydrazide-Hydrazone Derivatives as Potent Microtubule-Targeting Cytotoxic Agents against A549 Lung Cancer Cells.
    Das Mukherjee D, Kumar NM, Tantak MP, Das A, Ganguli A, Datta S, Kumar D, Chakrabarti G.
    Biochemistry; 2016 May 31; 55(21):3020-35. PubMed ID: 27110637
    [Abstract] [Full Text] [Related]

  • 11. Pyrrolotetrazinones deazaanalogues of temozolomide induce apoptosis in Jurkat cell line: involvement of tubulin polymerization inhibition.
    Viola G, Cecconet L, Leszl A, Basso G, Brun P, Salvador A, Dall'Acqua F, Diana P, Barraja P, Cirrincione G.
    Cancer Chemother Pharmacol; 2009 Nov 31; 64(6):1235-51. PubMed ID: 19363609
    [Abstract] [Full Text] [Related]

  • 12. Discovery of novel 2-N-aryl-substituted benzenesulfonamidoacetamides: orally bioavailable tubulin polymerization inhibitors with marked antitumor activities.
    Liu Z, Zhou Z, Tian W, Fan X, Xue D, Yu L, Yu Q, Long YQ.
    ChemMedChem; 2012 Apr 31; 7(4):680-93. PubMed ID: 22311585
    [Abstract] [Full Text] [Related]

  • 13. Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.
    Wong VK, Chiu P, Chung SS, Chow LM, Zhao YZ, Yang BB, Ko BC.
    Clin Cancer Res; 2005 Aug 15; 11(16):6002-11. PubMed ID: 16115945
    [Abstract] [Full Text] [Related]

  • 14. Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product.
    Wipf P, Graham TH, Vogt A, Sikorski RP, Ducruet AP, Lazo JS.
    Chem Biol Drug Des; 2006 Jan 15; 67(1):66-73. PubMed ID: 16492150
    [Abstract] [Full Text] [Related]

  • 15. Quinolone analogue inhibits tubulin polymerization and induces apoptosis via Cdk1-involved signaling pathways.
    Chen YC, Lu PH, Pan SL, Teng CM, Kuo SC, Lin TP, Ho YF, Huang YC, Guh JH.
    Biochem Pharmacol; 2007 Jun 30; 74(1):10-9. PubMed ID: 17475221
    [Abstract] [Full Text] [Related]

  • 16. Tubulozole-induced G2/M cell cycle arrest in human colon cancer cells through formation of microtubule polymerization mediated by ERK1/2 and Chk1 kinase activation.
    Chou YH, Ho YS, Wu CC, Chai CY, Chen SC, Lee CH, Tsai PS, Wu CH.
    Food Chem Toxicol; 2007 Aug 30; 45(8):1356-67. PubMed ID: 17329004
    [Abstract] [Full Text] [Related]

  • 17. N-(4-iodophenyl)-N'-(2-chloroethyl)urea as a microtubule disrupter: in vitro and in vivo profiling of antitumoral activity on CT-26 murine colon carcinoma cell line cultured and grafted to mice.
    Borel M, Degoul F, Communal Y, Mounetou E, Bouchon B, C-Gaudreault R, Madelmont JC, Miot-Noirault E.
    Br J Cancer; 2007 Jun 04; 96(11):1684-91. PubMed ID: 17486131
    [Abstract] [Full Text] [Related]

  • 18. Colchicine derivatives with potent anticancer activity and reduced P-glycoprotein induction liability.
    Singh B, Kumar A, Joshi P, Guru SK, Kumar S, Wani ZA, Mahajan G, Hussain A, Qazi AK, Kumar A, Bharate SS, Gupta BD, Sharma PR, Hamid A, Saxena AK, Mondhe DM, Bhushan S, Bharate SB, Vishwakarma RA.
    Org Biomol Chem; 2015 May 28; 13(20):5674-89. PubMed ID: 25895604
    [Abstract] [Full Text] [Related]

  • 19. A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors.
    Tahir SK, Han EK, Credo B, Jae HS, Pietenpol JA, Scatena CD, Wu-Wong JR, Frost D, Sham H, Rosenberg SH, Ng SC.
    Cancer Res; 2001 Jul 15; 61(14):5480-5. PubMed ID: 11454695
    [Abstract] [Full Text] [Related]

  • 20. A novel microtubule depolymerizing colchicine analogue triggers apoptosis and autophagy in HCT-116 colon cancer cells.
    Kumar A, Singh B, Sharma PR, Bharate SB, Saxena AK, Mondhe DM.
    Cell Biochem Funct; 2016 Mar 15; 34(2):69-81. PubMed ID: 26919061
    [Abstract] [Full Text] [Related]

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