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Journal Abstract Search

364 related items for PubMed ID: 26507467

  • 1. Multitarget Strategy to Address Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and Computational Studies of Coumarin-Based Derivatives.
    Montanari S, Bartolini M, Neviani P, Belluti F, Gobbi S, Pruccoli L, Tarozzi A, Falchi F, Andrisano V, Miszta P, Cavalli A, Filipek S, Bisi A, Rampa A.
    ChemMedChem; 2016 Jun 20; 11(12):1296-308. PubMed ID: 26507467
    [Abstract] [Full Text] [Related]

  • 2. 3-Aryl Coumarin Derivatives Bearing Aminoalkoxy Moiety as Multi-Target-Directed Ligands against Alzheimer's Disease.
    Abdshahzadeh H, Golshani M, Nadri H, Saberi Kia I, Abdolahi Z, Forootanfar H, Ameri A, Tüylü Küçükkılınç T, Ayazgok B, Jalili-Baleh L, Sadat Ebrahimi SE, Moghimi S, Haririan I, Khoobi M, Foroumadi A.
    Chem Biodivers; 2019 May 20; 16(5):e1800436. PubMed ID: 30957958
    [Abstract] [Full Text] [Related]

  • 3. Targeting Alzheimer's disease: Novel indanone hybrids bearing a pharmacophoric fragment of AP2238.
    Rizzo S, Bartolini M, Ceccarini L, Piazzi L, Gobbi S, Cavalli A, Recanatini M, Andrisano V, Rampa A.
    Bioorg Med Chem; 2010 Mar 01; 18(5):1749-60. PubMed ID: 20171894
    [Abstract] [Full Text] [Related]

  • 4. 3-(4-[[Benzyl(methyl)amino]methyl]phenyl)-6,7-dimethoxy-2H-2-chromenone (AP2238) inhibits both acetylcholinesterase and acetylcholinesterase-induced beta-amyloid aggregation: a dual function lead for Alzheimer's disease therapy.
    Piazzi L, Rampa A, Bisi A, Gobbi S, Belluti F, Cavalli A, Bartolini M, Andrisano V, Valenti P, Recanatini M.
    J Med Chem; 2003 Jun 05; 46(12):2279-82. PubMed ID: 12773032
    [Abstract] [Full Text] [Related]

  • 5. Multiple Ligands Targeting Cholinesterases and β-Amyloid: Synthesis, Biological Evaluation of Heterodimeric Compounds with Benzylamine Pharmacophore.
    Szałaj N, Bajda M, Dudek K, Brus B, Gobec S, Malawska B.
    Arch Pharm (Weinheim); 2015 Aug 05; 348(8):556-63. PubMed ID: 26032855
    [Abstract] [Full Text] [Related]

  • 6. Synthesis, Biological Evaluation, and Molecular Docking of 8-imino-2-oxo-2H,8H-pyrano[2,3-f]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease.
    Shaik JB, Palaka BK, Penumala M, Eadlapalli S, Darla Mark M, Ampasala DR, Vadde R, Amooru Gangaiah D.
    Chem Biol Drug Des; 2016 Jul 05; 88(1):43-53. PubMed ID: 26833890
    [Abstract] [Full Text] [Related]

  • 7. Discovery of Potent Dual Binding Site Acetylcholinesterase Inhibitors via Homo- and Heterodimerization of Coumarin-Based Moieties.
    Pisani L, Catto M, De Palma A, Farina R, Cellamare S, Altomare CD.
    ChemMedChem; 2017 Aug 22; 12(16):1349-1358. PubMed ID: 28570763
    [Abstract] [Full Text] [Related]

  • 8. The bivalent ligand approach as a tool for improving the in vitro anti-Alzheimer multitarget profile of dimebon.
    Rosini M, Simoni E, Bartolini M, Soriano E, Marco-Contelles J, Andrisano V, Monti B, Windisch M, Hutter-Paier B, McClymont DW, Mellor IR, Bolognesi ML.
    ChemMedChem; 2013 Aug 22; 8(8):1276-81. PubMed ID: 23824986
    [No Abstract] [Full Text] [Related]

  • 9. Design and synthesis of novel coumarin derivatives as potential acetylcholinesterase inhibitors for Alzheimer's disease.
    Amin KM, Abdel Rahman DE, Abdelrasheed Allam H, El-Zoheiry HH.
    Bioorg Chem; 2021 May 22; 110():104792. PubMed ID: 33799178
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, biological evaluation, and molecular modeling of donepezil and N-[(5-(benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine hybrids as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
    Bolea I, Juárez-Jiménez J, de Los Ríos C, Chioua M, Pouplana R, Luque FJ, Unzeta M, Marco-Contelles J, Samadi A.
    J Med Chem; 2011 Dec 22; 54(24):8251-70. PubMed ID: 22023459
    [Abstract] [Full Text] [Related]

  • 11. Extensive SAR and computational studies of 3-{4-[(benzylmethylamino)methyl]phenyl}-6,7-dimethoxy-2H-2-chromenone (AP2238) derivatives.
    Piazzi L, Cavalli A, Belluti F, Bisi A, Gobbi S, Rizzo S, Bartolini M, Andrisano V, Recanatini M, Rampa A.
    J Med Chem; 2007 Aug 23; 50(17):4250-4. PubMed ID: 17655212
    [Abstract] [Full Text] [Related]

  • 12. Design, synthesis and biological evaluation of coumarin alkylamines as potent and selective dual binding site inhibitors of acetylcholinesterase.
    Catto M, Pisani L, Leonetti F, Nicolotti O, Pesce P, Stefanachi A, Cellamare S, Carotti A.
    Bioorg Med Chem; 2013 Jan 01; 21(1):146-52. PubMed ID: 23199476
    [Abstract] [Full Text] [Related]

  • 13. Structure-activity relationship studies of benzyl-, phenethyl-, and pyridyl-substituted tetrahydroacridin-9-amines as multitargeting agents to treat Alzheimer's disease.
    Osman W, Mohamed T, Sit VM, Vasefi MS, Beazely MA, Rao PP.
    Chem Biol Drug Des; 2016 Nov 01; 88(5):710-723. PubMed ID: 27282589
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and evaluation of flavonoid derivatives as potential multifunctional acetylcholinesterase inhibitors against Alzheimer's disease.
    Li RS, Wang XB, Hu XJ, Kong LY.
    Bioorg Med Chem Lett; 2013 May 01; 23(9):2636-41. PubMed ID: 23511019
    [Abstract] [Full Text] [Related]

  • 15. Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents.
    Shaik JB, Palaka BK, Penumala M, Kotapati KV, Devineni SR, Eadlapalli S, Darla MM, Ampasala DR, Vadde R, Amooru GD.
    Eur J Med Chem; 2016 Jan 01; 107():219-32. PubMed ID: 26588065
    [Abstract] [Full Text] [Related]

  • 16. Design and Synthesis of Novel Arylisoxazole-Chromenone Carboxamides: Investigation of Biological Activities Associated with Alzheimer's Disease.
    Saeedi M, Rastegari A, Hariri R, Mirfazli SS, Mahdavi M, Edraki N, Firuzi O, Akbarzadeh T.
    Chem Biodivers; 2020 May 01; 17(5):e1900746. PubMed ID: 32154628
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and screening of triazolopyrimidine scaffold as multi-functional agents for Alzheimer's disease therapies.
    Kumar J, Meena P, Singh A, Jameel E, Maqbool M, Mobashir M, Shandilya A, Tiwari M, Hoda N, Jayaram B.
    Eur J Med Chem; 2016 Aug 25; 119():260-77. PubMed ID: 27227482
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis and biological activity of multifunctional α,β-unsaturated carbonyl scaffolds for Alzheimer's disease.
    Bag S, Ghosh S, Tulsan R, Sood A, Zhou W, Schifone C, Foster M, LeVine H, Török B, Török M.
    Bioorg Med Chem Lett; 2013 May 01; 23(9):2614-8. PubMed ID: 23540646
    [Abstract] [Full Text] [Related]

  • 19. Isoxazolotacrines as non-toxic and selective butyrylcholinesterase inhibitors for Alzheimer's disease.
    Cherif O, Allouche F, Chabchoub F, Chioua M, Soriano E, Yañez M, Cacabelos R, Romero A, López MG, Marco-Contelles J.
    Future Med Chem; 2014 May 01; 6(17):1883-91. PubMed ID: 25495982
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and biological evaluation of 4-arylcoumarins as potential anti-Alzheimer's disease agents.
    Yun Y, Yang J, Miao Y, Wang X, Sun J.
    Bioorg Med Chem Lett; 2020 Feb 15; 30(4):126900. PubMed ID: 31882295
    [Abstract] [Full Text] [Related]

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