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169 related items for PubMed ID: 26514521

  • 21. Nec-1 enhances shikonin-induced apoptosis in leukemia cells by inhibition of RIP-1 and ERK1/2.
    Han W, Xie J, Fang Y, Wang Z, Pan H.
    Int J Mol Sci; 2012; 13(6):7212-7225. PubMed ID: 22837689
    [Abstract] [Full Text] [Related]

  • 22. Mechanism of juglone-induced apoptosis of MCF-7 cells by the mitochondrial pathway.
    Ji YB, Xin GS, Qu ZY, Zou X, Yu M.
    Genet Mol Res; 2016 Jul 25; 15(3):. PubMed ID: 27525860
    [Abstract] [Full Text] [Related]

  • 23. Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells.
    Sun W, Wu X, Gao H, Yu J, Zhao W, Lu JJ, Wang J, Du G, Chen X.
    Free Radic Biol Med; 2017 Jul 25; 108():433-444. PubMed ID: 28414098
    [Abstract] [Full Text] [Related]

  • 24. Reactive oxygen species-mediated activation of the Akt/ASK1/p38 signaling cascade and p21(Cip1) downregulation are required for shikonin-induced apoptosis.
    Ahn J, Won M, Choi JH, Kim YS, Jung CR, Im DS, Kyun ML, Lee K, Song KB, Chung KS.
    Apoptosis; 2013 Jul 25; 18(7):870-81. PubMed ID: 23546866
    [Abstract] [Full Text] [Related]

  • 25. Shikonin-induced Apoptosis of Colon Cancer Cells Is Reduced by Peroxiredoxin V Expression.
    Chandimali N, Sun HN, Kong LZ, Zhen X, Liu R, Kwon T, Lee DS.
    Anticancer Res; 2019 Nov 25; 39(11):6115-6123. PubMed ID: 31704839
    [Abstract] [Full Text] [Related]

  • 26. Chimaphilin induces apoptosis in human breast cancer MCF-7 cells through a ROS-mediated mitochondrial pathway.
    Ma WD, Zou YP, Wang P, Yao XH, Sun Y, Duan MH, Fu YJ, Yu B.
    Food Chem Toxicol; 2014 Aug 25; 70():1-8. PubMed ID: 24793375
    [Abstract] [Full Text] [Related]

  • 27. Shikonin induces mitochondria-mediated apoptosis and enhances chemotherapeutic sensitivity of gastric cancer through reactive oxygen species.
    Liang W, Cai A, Chen G, Xi H, Wu X, Cui J, Zhang K, Zhao X, Yu J, Wei B, Chen L.
    Sci Rep; 2016 Dec 01; 6():38267. PubMed ID: 27905569
    [Abstract] [Full Text] [Related]

  • 28. Shikonin in breast cancer treatment: a comprehensive review of molecular pathways and innovative strategies.
    Iranzadeh S, Dalil D, Kohansal S, Isakhani M.
    J Pharm Pharmacol; 2024 Aug 02; 76(8):967-982. PubMed ID: 38652046
    [Abstract] [Full Text] [Related]

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  • 30. An oxidative stress mechanism of shikonin in human glioma cells.
    Yang JT, Li ZL, Wu JY, Lu FJ, Chen CH.
    PLoS One; 2014 Aug 02; 9(4):e94180. PubMed ID: 24714453
    [Abstract] [Full Text] [Related]

  • 31. Advance in Anti-tumor Mechanisms of Shikonin, Alkannin and their Derivatives.
    Zhang X, Cui JH, Meng QQ, Li SS, Zhou W, Xiao S.
    Mini Rev Med Chem; 2018 Aug 02; 18(2):164-172. PubMed ID: 28245783
    [Abstract] [Full Text] [Related]

  • 32. Shikonin-induced necroptosis in nasopharyngeal carcinoma cells via ROS overproduction and upregulation of RIPK1/RIPK3/MLKL expression.
    Liu T, Sun X, Cao Z.
    Onco Targets Ther; 2019 Aug 02; 12():2605-2614. PubMed ID: 31118661
    [Abstract] [Full Text] [Related]

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  • 34. Bufalin Induces Programmed Necroptosis in Triple-Negative Breast Cancer Drug-Resistant Cell Lines through RIP1/ROS-Mediated Pathway.
    Liu XD, Song CY, Kong CC, Tian X.
    Chin J Integr Med; 2022 Oct 02; 28(10):900-908. PubMed ID: 34826043
    [Abstract] [Full Text] [Related]

  • 35. Involvement of reactive oxygen species, but not mitochondrial permeability transition in the apoptotic induction of human SK-Hep-1 hepatoma cells by shikonin.
    Chen CH, Chern CL, Lin CC, Lu FJ, Shih MK, Hsieh PY, Liu TZ.
    Planta Med; 2003 Dec 02; 69(12):1119-24. PubMed ID: 14750028
    [Abstract] [Full Text] [Related]

  • 36. Shikonin selectively induces apoptosis in human prostate cancer cells through the endoplasmic reticulum stress and mitochondrial apoptotic pathway.
    Gara RK, Srivastava VK, Duggal S, Bagga JK, Bhatt M, Sanyal S, Mishra DP.
    J Biomed Sci; 2015 Apr 01; 22(1):26. PubMed ID: 25879420
    [Abstract] [Full Text] [Related]

  • 37. Shikonin-induced apoptosis involves caspase-3 activity in a human bladder cancer cell line (T24).
    Yeh CC, Kuo HM, Li TM, Lin JP, Yu FS, Lu HF, Chung JG, Yang JS.
    In Vivo; 2007 Apr 01; 21(6):1011-9. PubMed ID: 18210748
    [Abstract] [Full Text] [Related]

  • 38. Shikonin circumvents cancer drug resistance by induction of a necroptotic death.
    Han W, Li L, Qiu S, Lu Q, Pan Q, Gu Y, Luo J, Hu X.
    Mol Cancer Ther; 2007 May 01; 6(5):1641-9. PubMed ID: 17513612
    [Abstract] [Full Text] [Related]

  • 39. PKM2 Inhibitor Shikonin Overcomes the Cisplatin Resistance in Bladder Cancer by Inducing Necroptosis.
    Wang Y, Hao F, Nan Y, Qu L, Na W, Jia C, Chen X.
    Int J Biol Sci; 2018 May 01; 14(13):1883-1891. PubMed ID: 30443191
    [Abstract] [Full Text] [Related]

  • 40. Shikonin inhibits gefitinib-resistant non-small cell lung cancer by inhibiting TrxR and activating the EGFR proteasomal degradation pathway.
    Li X, Fan XX, Jiang ZB, Loo WT, Yao XJ, Leung EL, Chow LW, Liu L.
    Pharmacol Res; 2017 Jan 01; 115():45-55. PubMed ID: 27864022
    [Abstract] [Full Text] [Related]

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