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756 related items for PubMed ID: 26539645

  • 1. Myristic acid potentiates palmitic acid-induced lipotoxicity and steatohepatitis associated with lipodystrophy by sustaning de novo ceramide synthesis.
    Martínez L, Torres S, Baulies A, Alarcón-Vila C, Elena M, Fabriàs G, Casas J, Caballeria J, Fernandez-Checa JC, García-Ruiz C.
    Oncotarget; 2015 Dec 08; 6(39):41479-96. PubMed ID: 26539645
    [Abstract] [Full Text] [Related]

  • 2. Sab (Sh3bp5) dependence of JNK mediated inhibition of mitochondrial respiration in palmitic acid induced hepatocyte lipotoxicity.
    Win S, Than TA, Le BH, García-Ruiz C, Fernandez-Checa JC, Kaplowitz N.
    J Hepatol; 2015 Jun 08; 62(6):1367-74. PubMed ID: 25666017
    [Abstract] [Full Text] [Related]

  • 3. Hepatocyte free cholesterol lipotoxicity results from JNK1-mediated mitochondrial injury and is HMGB1 and TLR4-dependent.
    Gan LT, Van Rooyen DM, Koina ME, McCuskey RS, Teoh NC, Farrell GC.
    J Hepatol; 2014 Dec 08; 61(6):1376-84. PubMed ID: 25064435
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  • 4. Essential role of Nrf2 in the protective effect of lipoic acid against lipoapoptosis in hepatocytes.
    Pilar Valdecantos M, Prieto-Hontoria PL, Pardo V, Módol T, Santamaría B, Weber M, Herrero L, Serra D, Muntané J, Cuadrado A, Moreno-Aliaga MJ, Alfredo Martínez J, Valverde ÁM.
    Free Radic Biol Med; 2015 Jul 08; 84():263-278. PubMed ID: 25841776
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  • 5. Therapeutic effect and autophagy regulation of myriocin in nonalcoholic steatohepatitis.
    Yang RX, Pan Q, Liu XL, Zhou D, Xin FZ, Zhao ZH, Zhang RN, Zeng J, Qiao L, Hu CX, Xu GW, Fan JG.
    Lipids Health Dis; 2019 Oct 21; 18(1):179. PubMed ID: 31639005
    [Abstract] [Full Text] [Related]

  • 6. C/EBP homologous protein modulates liraglutide-mediated attenuation of non-alcoholic steatohepatitis.
    Rahman K, Liu Y, Kumar P, Smith T, Thorn NE, Farris AB, Anania FA.
    Lab Invest; 2016 Aug 21; 96(8):895-908. PubMed ID: 27239734
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  • 7. Attenuated lipotoxicity and apoptosis is linked to exogenous and endogenous augmenter of liver regeneration by different pathways.
    Weiss TS, Lupke M, Ibrahim S, Buechler C, Lorenz J, Ruemmele P, Hofmann U, Melter M, Dayoub R.
    PLoS One; 2017 Aug 21; 12(9):e0184282. PubMed ID: 28877220
    [Abstract] [Full Text] [Related]

  • 8. Elevation of liver endoplasmic reticulum stress in a modified choline-deficient l-amino acid-defined diet-fed non-alcoholic steatohepatitis mouse model.
    Muraki Y, Makita Y, Yamasaki M, Amano Y, Matsuo T.
    Biochem Biophys Res Commun; 2017 May 06; 486(3):632-638. PubMed ID: 28322783
    [Abstract] [Full Text] [Related]

  • 9. Hepatocyte X-box binding protein 1 deficiency increases liver injury in mice fed a high-fat/sugar diet.
    Liu X, Henkel AS, LeCuyer BE, Schipma MJ, Anderson KA, Green RM.
    Am J Physiol Gastrointest Liver Physiol; 2015 Dec 15; 309(12):G965-74. PubMed ID: 26472223
    [Abstract] [Full Text] [Related]

  • 10. Oleic acid protects saturated fatty acid mediated lipotoxicity in hepatocytes and rat of non-alcoholic steatohepatitis.
    Chen X, Li L, Liu X, Luo R, Liao G, Li L, Liu J, Cheng J, Lu Y, Chen Y.
    Life Sci; 2018 Jun 15; 203():291-304. PubMed ID: 29709653
    [Abstract] [Full Text] [Related]

  • 11. Targeting alkaline ceramidase 3 alleviates the severity of nonalcoholic steatohepatitis by reducing oxidative stress.
    Wang K, Li C, Lin X, Sun H, Xu R, Li Q, Wei Y, Li Y, Qian J, Liu C, Zhang Q, Yu S, Cui Z, Huang X, Zhu B, Zhou J, Mao C.
    Cell Death Dis; 2020 Jan 16; 11(1):28. PubMed ID: 31949129
    [Abstract] [Full Text] [Related]

  • 12. Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner.
    Kakazu E, Mauer AS, Yin M, Malhi H.
    J Lipid Res; 2016 Feb 16; 57(2):233-45. PubMed ID: 26621917
    [Abstract] [Full Text] [Related]

  • 13. Hepatic FTO expression is increased in NASH and its silencing attenuates palmitic acid-induced lipotoxicity.
    Lim A, Zhou J, Sinha RA, Singh BK, Ghosh S, Lim KH, Chow PK, Woon ECY, Yen PM.
    Biochem Biophys Res Commun; 2016 Oct 21; 479(3):476-481. PubMed ID: 27651333
    [Abstract] [Full Text] [Related]

  • 14. Toyocamycin attenuates free fatty acid-induced hepatic steatosis and apoptosis in cultured hepatocytes and ameliorates nonalcoholic fatty liver disease in mice.
    Takahara I, Akazawa Y, Tabuchi M, Matsuda K, Miyaaki H, Kido Y, Kanda Y, Taura N, Ohnita K, Takeshima F, Sakai Y, Eguchi S, Nakashima M, Nakao K.
    PLoS One; 2017 Oct 21; 12(3):e0170591. PubMed ID: 28278289
    [Abstract] [Full Text] [Related]

  • 15. Palmitic acid induces autophagy in hepatocytes via JNK2 activation.
    Tu QQ, Zheng RY, Li J, Hu L, Chang YX, Li L, Li MH, Wang RY, Huang DD, Wu MC, Hu HP, Chen L, Wang HY.
    Acta Pharmacol Sin; 2014 Apr 21; 35(4):504-12. PubMed ID: 24608675
    [Abstract] [Full Text] [Related]

  • 16. Palmitate activation by fatty acid transport protein 4 as a model system for hepatocellular apoptosis and steatosis.
    Seeßle J, Liebisch G, Schmitz G, Stremmel W, Chamulitrat W.
    Biochim Biophys Acta; 2015 May 21; 1851(5):549-65. PubMed ID: 25603556
    [Abstract] [Full Text] [Related]

  • 17. Non-Alcoholic Fatty Liver Disease.
    Engin A.
    Adv Exp Med Biol; 2017 May 21; 960():443-467. PubMed ID: 28585211
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  • 18. ASMase regulates autophagy and lysosomal membrane permeabilization and its inhibition prevents early stage non-alcoholic steatohepatitis.
    Fucho R, Martínez L, Baulies A, Torres S, Tarrats N, Fernandez A, Ribas V, Astudillo AM, Balsinde J, Garcia-Rovés P, Elena M, Bergheim I, Lotersztajn S, Trautwein C, Appelqvist H, Paton AW, Paton JC, Czaja MJ, Kaplowitz N, Fernandez-Checa JC, García-Ruiz C.
    J Hepatol; 2014 Nov 21; 61(5):1126-34. PubMed ID: 24946279
    [Abstract] [Full Text] [Related]

  • 19. IRE1A Stimulates Hepatocyte-Derived Extracellular Vesicles That Promote Inflammation in Mice With Steatohepatitis.
    Dasgupta D, Nakao Y, Mauer AS, Thompson JM, Sehrawat TS, Liao CY, Krishnan A, Lucien F, Guo Q, Liu M, Xue F, Fukushima M, Katsumi T, Bansal A, Pandey MK, Maiers JL, DeGrado T, Ibrahim SH, Revzin A, Pavelko KD, Barry MA, Kaufman RJ, Malhi H.
    Gastroenterology; 2020 Oct 21; 159(4):1487-1503.e17. PubMed ID: 32574624
    [Abstract] [Full Text] [Related]

  • 20. Peroxisome proliferator-activated receptor-delta agonist ameliorated inflammasome activation in nonalcoholic fatty liver disease.
    Lee HJ, Yeon JE, Ko EJ, Yoon EL, Suh SJ, Kang K, Kim HR, Kang SH, Yoo YJ, Je J, Lee BJ, Kim JH, Seo YS, Yim HJ, Byun KS.
    World J Gastroenterol; 2015 Dec 07; 21(45):12787-99. PubMed ID: 26668503
    [Abstract] [Full Text] [Related]

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