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326 related items for PubMed ID: 26558612

  • 21. A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice.
    Zins K, Lucas T, Reichl P, Abraham D, Aharinejad S.
    PLoS One; 2013; 8(9):e74924. PubMed ID: 24040362
    [Abstract] [Full Text] [Related]

  • 22. Small molecule targeting Cdc42-intersectin interaction disrupts Golgi organization and suppresses cell motility.
    Friesland A, Zhao Y, Chen YH, Wang L, Zhou H, Lu Q.
    Proc Natl Acad Sci U S A; 2013 Jan 22; 110(4):1261-6. PubMed ID: 23284167
    [Abstract] [Full Text] [Related]

  • 23. Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer.
    Humphries-Bickley T, Castillo-Pichardo L, Hernandez-O'Farrill E, Borrero-Garcia LD, Forestier-Roman I, Gerena Y, Blanco M, Rivera-Robles MJ, Rodriguez-Medina JR, Cubano LA, Vlaar CP, Dharmawardhane S.
    Mol Cancer Ther; 2017 May 22; 16(5):805-818. PubMed ID: 28450422
    [Abstract] [Full Text] [Related]

  • 24. Molecular basis for Rac1 recognition by guanine nucleotide exchange factors.
    Karnoub AE, Worthylake DK, Rossman KL, Pruitt WM, Campbell SL, Sondek J, Der CJ.
    Nat Struct Biol; 2001 Dec 22; 8(12):1037-41. PubMed ID: 11685227
    [Abstract] [Full Text] [Related]

  • 25. How Vav proteins discriminate the GTPases Rac1 and RhoA from Cdc42.
    Movilla N, Dosil M, Zheng Y, Bustelo XR.
    Oncogene; 2001 Dec 06; 20(56):8057-65. PubMed ID: 11781818
    [Abstract] [Full Text] [Related]

  • 26. The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor.
    Mishima W, Suzuki A, Yamaji S, Yoshimi R, Ueda A, Kaneko T, Tanaka J, Miwa Y, Ohno S, Ishigatsubo Y.
    Genes Cells; 2004 Mar 06; 9(3):193-204. PubMed ID: 15005707
    [Abstract] [Full Text] [Related]

  • 27. Developmental expression of three small GTPases in the mouse eye.
    Mitchell DC, Bryan BA, Liu JP, Liu WB, Zhang L, Qu J, Zhou X, Liu M, Li DW.
    Mol Vis; 2007 Jul 13; 13():1144-53. PubMed ID: 17653061
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  • 28. Evaluating the enantiospecific differences of non-steroidal anti-inflammatory drugs (NSAIDs) using an ecotoxicity bioassay test battery.
    Neale PA, Branch A, Khan SJ, Leusch FDL.
    Sci Total Environ; 2019 Dec 01; 694():133659. PubMed ID: 31386950
    [Abstract] [Full Text] [Related]

  • 29. Cdc42 and Rac1 activity is reduced in human pheochromocytoma and correlates with FARP1 and ARHGEF1 expression.
    Croisé P, Houy S, Gand M, Lanoix J, Calco V, Tóth P, Brunaud L, Lomazzi S, Paramithiotis E, Chelsky D, Ory S, Gasman S.
    Endocr Relat Cancer; 2016 Apr 01; 23(4):281-93. PubMed ID: 26911374
    [Abstract] [Full Text] [Related]

  • 30. Cooperative anti-invasive effect of Cdc42/Rac1 activation and ROCK inhibition in SW620 colorectal cancer cells with elevated blebbing activity.
    de Toledo M, Anguille C, Roger L, Roux P, Gadea G.
    PLoS One; 2012 Apr 01; 7(11):e48344. PubMed ID: 23144867
    [Abstract] [Full Text] [Related]

  • 31. ROCK and nuclear factor-kappaB-dependent activation of cyclooxygenase-2 by Rho GTPases: effects on tumor growth and therapeutic consequences.
    Benitah SA, Valerón PF, Lacal JC.
    Mol Biol Cell; 2003 Jul 01; 14(7):3041-54. PubMed ID: 12857884
    [Abstract] [Full Text] [Related]

  • 32. Prostaglandin E2-mediated migration of human trophoblast requires RAC1 and CDC42.
    Nicola C, Lala PK, Chakraborty C.
    Biol Reprod; 2008 Jun 01; 78(6):976-82. PubMed ID: 18235104
    [Abstract] [Full Text] [Related]

  • 33. Cardiomyocytes, cardiac endothelial cells and fibroblasts contribute to anthracycline-induced cardiac injury through RAS-homologous small GTPases RAC1 and CDC42.
    Kücük P, Abbey L, Schmitt J, Henninger C, Fritz G.
    Pharmacol Res; 2024 May 01; 203():107165. PubMed ID: 38561112
    [Abstract] [Full Text] [Related]

  • 34. Neuroglobin Plays a Protective Role in Arsenite-Induced Cytotoxicity by Inhibition of Cdc42 and Rac1GTPases in Rat Cerebellar Granule Neurons.
    Liu X, Gao Y, An Y, Fu X, Li Y, Sun D, Wang J.
    Cell Physiol Biochem; 2015 May 01; 36(4):1613-27. PubMed ID: 26160017
    [Abstract] [Full Text] [Related]

  • 35. miR-148b-3p inhibits gastric cancer metastasis by inhibiting the Dock6/Rac1/Cdc42 axis.
    Li X, Jiang M, Chen D, Xu B, Wang R, Chu Y, Wang W, Zhou L, Lei Z, Nie Y, Fan D, Shang Y, Wu K, Liang J.
    J Exp Clin Cancer Res; 2018 Mar 27; 37(1):71. PubMed ID: 29587866
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  • 36. Optogenetic dissection of Rac1 and Cdc42 gradient shaping.
    de Beco S, Vaidžiulytė K, Manzi J, Dalier F, di Federico F, Cornilleau G, Dahan M, Coppey M.
    Nat Commun; 2018 Nov 16; 9(1):4816. PubMed ID: 30446664
    [Abstract] [Full Text] [Related]

  • 37. Modulation of the Pol II CTD Phosphorylation Code by Rac1 and Cdc42 Small GTPases in Cultured Human Cancer Cells and Its Implication for Developing a Synthetic-Lethal Cancer Therapy.
    Zhang B, Zhong X, Sauane M, Zhao Y, Zheng ZL.
    Cells; 2020 Mar 04; 9(3):. PubMed ID: 32143485
    [Abstract] [Full Text] [Related]

  • 38. Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity.
    Zins K, Gunawardhana S, Lucas T, Abraham D, Aharinejad S.
    J Transl Med; 2013 Nov 27; 11():295. PubMed ID: 24279335
    [Abstract] [Full Text] [Related]

  • 39. Thiopurine Prodrugs Mediate Immunosuppressive Effects by Interfering with Rac1 Protein Function.
    Shin JY, Wey M, Umutesi HG, Sun X, Simecka J, Heo J.
    J Biol Chem; 2016 Jun 24; 291(26):13699-714. PubMed ID: 27189938
    [Abstract] [Full Text] [Related]

  • 40. Regulation of platelet Rac1 and Cdc42 activation through interaction with calmodulin.
    Elsaraj SM, Bhullar RP.
    Biochim Biophys Acta; 2008 May 24; 1783(5):770-8. PubMed ID: 18328269
    [Abstract] [Full Text] [Related]

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