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163 related items for PubMed ID: 2655891

  • 1. Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002.
    Shimada T, Iwasaki M, Martin MV, Guengerich FP.
    Cancer Res; 1989 Jun 15; 49(12):3218-28. PubMed ID: 2655891
    [Abstract] [Full Text] [Related]

  • 2. Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons.
    Shimada T, Martin MV, Pruess-Schwartz D, Marnett LJ, Guengerich FP.
    Cancer Res; 1989 Nov 15; 49(22):6304-12. PubMed ID: 2509067
    [Abstract] [Full Text] [Related]

  • 3. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
    Shimada T, Hayes CL, Yamazaki H, Amin S, Hecht SS, Guengerich FP, Sutter TR.
    Cancer Res; 1996 Jul 01; 56(13):2979-84. PubMed ID: 8674051
    [Abstract] [Full Text] [Related]

  • 4. Inactivation of 1,3-, 1,6-, and 1,8-dinitropyrene by cytochrome P-450 enzymes in human and rat liver microsomes.
    Shimada T, Guengerich FP.
    Cancer Res; 1990 Apr 01; 50(7):2036-43. PubMed ID: 2180560
    [Abstract] [Full Text] [Related]

  • 5. Rat pulmonary microsomal cytochrome P-450 enzymes involved in the activation of procarcinogens.
    Shimada T, Yamazaki H, Mimura M, Guengerich FP.
    Mutat Res; 1992 Dec 16; 284(2):233-41. PubMed ID: 1281274
    [Abstract] [Full Text] [Related]

  • 6. Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes.
    Shimada T, Guengerich FP.
    Cancer Res; 1991 Oct 01; 51(19):5284-91. PubMed ID: 1913651
    [Abstract] [Full Text] [Related]

  • 7. Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.
    Shimada T, Yamazaki H, Mimura M, Wakamiya N, Ueng YF, Guengerich FP, Inui Y.
    Drug Metab Dispos; 1996 May 01; 24(5):515-22. PubMed ID: 8723730
    [Abstract] [Full Text] [Related]

  • 8. Activation and inactivation of carcinogenic dihaloalkanes and other compounds by glutathione S-transferase 5-5 in Salmonella typhimurium tester strain NM5004.
    Shimada T, Yamazaki H, Oda Y, Hiratsuka A, Watabe T, Guengerich FP.
    Chem Res Toxicol; 1996 May 01; 9(1):333-40. PubMed ID: 8924613
    [Abstract] [Full Text] [Related]

  • 9. Inhibition of human cytochrome P450-catalyzed oxidations of xenobiotics and procarcinogens by synthetic organoselenium compounds.
    Shimada T, El-Bayoumy K, Upadhyaya P, Sutter TR, Guengerich FP, Yamazaki H.
    Cancer Res; 1997 Nov 01; 57(21):4757-64. PubMed ID: 9354437
    [Abstract] [Full Text] [Related]

  • 10. Characterization of human lung microsomal cytochrome P-450 1A1 and its role in the oxidation of chemical carcinogens.
    Shimada T, Yun CH, Yamazaki H, Gautier JC, Beaune PH, Guengerich FP.
    Mol Pharmacol; 1992 May 01; 41(5):856-64. PubMed ID: 1588920
    [Abstract] [Full Text] [Related]

  • 11. Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver.
    Shimada T, Guengerich FP.
    Proc Natl Acad Sci U S A; 1989 Jan 01; 86(2):462-5. PubMed ID: 2492107
    [Abstract] [Full Text] [Related]

  • 12. Metabolic activation of environmental carcinogens and mutagens by human liver microsomes. Role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver.
    Shimada T, Okuda Y.
    Biochem Pharmacol; 1988 Feb 01; 37(3):459-65. PubMed ID: 3337745
    [Abstract] [Full Text] [Related]

  • 13. Use of a newly developed tester strain Salmonella typhimurium NM2009 for the study of metabolic activation of carcinogenic aromatic amines by rat liver microsomal cytochrome P-450 enzymes.
    Yamazaki H, Oda Y, Shimada T.
    Mutat Res; 1992 Oct 01; 272(2):183-92. PubMed ID: 1383750
    [Abstract] [Full Text] [Related]

  • 14. Activation of 6-aminochrysene to genotoxic products by different forms of rat liver cytochrome P450 in an O-acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).
    Yamazaki H, Shimada T.
    Biochem Pharmacol; 1992 Sep 01; 44(5):913-20. PubMed ID: 1530660
    [Abstract] [Full Text] [Related]

  • 15. Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.
    Oda Y, Aryal P, Terashita T, Gillam EM, Guengerich FP, Shimada T.
    Mutat Res; 2001 May 31; 492(1-2):81-90. PubMed ID: 11377247
    [Abstract] [Full Text] [Related]

  • 16. Roles of human liver cytochrome P4502C and 3A enzymes in the 3-hydroxylation of benzo(a)pyrene.
    Yun CH, Shimada T, Guengerich FP.
    Cancer Res; 1992 Apr 01; 52(7):1868-74. PubMed ID: 1551116
    [Abstract] [Full Text] [Related]

  • 17. Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.
    Butler MA, Iwasaki M, Guengerich FP, Kadlubar FF.
    Proc Natl Acad Sci U S A; 1989 Oct 01; 86(20):7696-700. PubMed ID: 2813353
    [Abstract] [Full Text] [Related]

  • 18. Metabolic oxidation of the carcinogens 4-aminobiphenyl and 4,4'-methylene-bis(2-chloroaniline) by human hepatic microsomes and by purified rat hepatic cytochrome P-450 monooxygenases.
    Butler MA, Guengerich FP, Kadlubar FF.
    Cancer Res; 1989 Jan 01; 49(1):25-31. PubMed ID: 2908851
    [Abstract] [Full Text] [Related]

  • 19. Inhibition of mutagenicity of food-derived heterocyclic amines by sulforaphane--a constituent of broccoli.
    Shishu, Kaur IP.
    Indian J Exp Biol; 2003 Mar 01; 41(3):216-9. PubMed ID: 15267150
    [Abstract] [Full Text] [Related]

  • 20. Purification and characterization of human liver microsomal cytochrome P-450 2A6.
    Yun CH, Shimada T, Guengerich FP.
    Mol Pharmacol; 1991 Nov 01; 40(5):679-85. PubMed ID: 1944238
    [Abstract] [Full Text] [Related]

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