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Journal Abstract Search


117 related items for PubMed ID: 2657723

  • 1. Determinants of EcoRI endonuclease sequence discrimination.
    Needels MC, Fried SR, Love R, Rosenberg JM, Boyer HW, Greene PJ.
    Proc Natl Acad Sci U S A; 1989 May; 86(10):3579-83. PubMed ID: 2657723
    [Abstract] [Full Text] [Related]

  • 2. Asn141 is essential for DNA recognition by EcoRI restriction endonuclease.
    Fritz A, Küster W, Alves J.
    FEBS Lett; 1998 Oct 30; 438(1-2):66-70. PubMed ID: 9821960
    [Abstract] [Full Text] [Related]

  • 3. Thermodynamic and kinetic basis for the relaxed DNA sequence specificity of "promiscuous" mutant EcoRI endonucleases.
    Sapienza PJ, Dela Torre CA, McCoy WH, Jana SV, Jen-Jacobson L.
    J Mol Biol; 2005 Apr 29; 348(2):307-24. PubMed ID: 15811370
    [Abstract] [Full Text] [Related]

  • 4. Changing the hydrogen-bonding potential in the DNA binding site of EcoRI by site-directed mutagenesis drastically reduces the enzymatic activity, not, however, the preference of this restriction endonuclease for cleavage within the site-GAATTC-.
    Alves J, Rüter T, Geiger R, Fliess A, Maass G, Pingoud A.
    Biochemistry; 1989 Mar 21; 28(6):2678-84. PubMed ID: 2659077
    [Abstract] [Full Text] [Related]

  • 5. Substrate recognition by the EcoRI endonuclease.
    Heitman J, Model P.
    Proteins; 1990 Mar 21; 7(2):185-97. PubMed ID: 2139225
    [Abstract] [Full Text] [Related]

  • 6. Genetic engineering of EcoRI mutants with altered amino acid residues in the DNA binding site: physicochemical investigations give evidence for an altered monomer/dimer equilibrium for the Gln144Lys145 and Gln144Lys145Lys200 mutants.
    Geiger R, Rüter T, Alves J, Fliess A, Wolfes H, Pingoud V, Urbanke C, Maass G, Pingoud A, Düsterhöft A.
    Biochemistry; 1989 Mar 21; 28(6):2667-77. PubMed ID: 2499352
    [Abstract] [Full Text] [Related]

  • 7. Temperature-sensitive mutants of the EcoRI endonuclease.
    Muir RS, Flores H, Zinder ND, Model P, Soberon X, Heitman J.
    J Mol Biol; 1997 Dec 19; 274(5):722-37. PubMed ID: 9405154
    [Abstract] [Full Text] [Related]

  • 8. Probing the function of individual amino acid residues in the DNA binding site of the EcoRI restriction endonuclease by analysing the toxicity of genetically engineered mutants.
    Oelgeschläger T, Geiger R, Rüter T, Alves J, Fliess A, Pingoud A.
    Gene; 1990 Apr 30; 89(1):19-27. PubMed ID: 2142667
    [Abstract] [Full Text] [Related]

  • 9. How the EcoRI endonuclease recognizes and cleaves DNA.
    Heitman J.
    Bioessays; 1992 Jul 30; 14(7):445-54. PubMed ID: 1445286
    [Abstract] [Full Text] [Related]

  • 10. Mutants of the EcoRI endonuclease with promiscuous substrate specificity implicate residues involved in substrate recognition.
    Heitman J, Model P.
    EMBO J; 1990 Oct 30; 9(10):3369-78. PubMed ID: 2209548
    [Abstract] [Full Text] [Related]

  • 11. Probing the role of glutamic acid 144 in the EcoRI endonuclease using aspartic acid and glutamine replacements.
    Hager PW, Reich NO, Day JP, Coche TG, Boyer HW, Rosenberg JM, Greene PJ.
    J Biol Chem; 1990 Dec 15; 265(35):21520-6. PubMed ID: 2254311
    [Abstract] [Full Text] [Related]

  • 12. Mutational analysis of the function of Gln115 in the EcoRI restriction endonuclease, a critical amino acid for recognition of the inner thymidine residue in the sequence -GAATTC- and for coupling specific DNA binding to catalysis.
    Jeltsch A, Alves J, Oelgeschläger T, Wolfes H, Maass G, Pingoud A.
    J Mol Biol; 1993 Jan 05; 229(1):221-34. PubMed ID: 8421302
    [Abstract] [Full Text] [Related]

  • 13. Structural and thermodynamic basis for enhanced DNA binding by a promiscuous mutant EcoRI endonuclease.
    Sapienza PJ, Rosenberg JM, Jen-Jacobson L.
    Structure; 2007 Nov 05; 15(11):1368-82. PubMed ID: 17997963
    [Abstract] [Full Text] [Related]

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  • 16. Saturation mutagenesis of His114 of EcoRI reveals relaxed-specificity mutants.
    Flores H, Osuna J, Heitman J, Soberón X.
    Gene; 1995 May 19; 157(1-2):295-301. PubMed ID: 7607511
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  • 18. Structure-based redesign of the catalytic/metal binding site of Cfr10I restriction endonuclease reveals importance of spatial rather than sequence conservation of active centre residues.
    Skirgaila R, Grazulis S, Bozic D, Huber R, Siksnys V.
    J Mol Biol; 1998 Jun 05; 279(2):473-81. PubMed ID: 9642051
    [Abstract] [Full Text] [Related]

  • 19. Clustering of null mutations in the EcoRI endonuclease.
    Yanofsky SD, Love R, McClarin JA, Rosenberg JM, Boyer HW, Greene PJ.
    Proteins; 1987 Jun 05; 2(4):273-82. PubMed ID: 2834717
    [Abstract] [Full Text] [Related]

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