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Journal Abstract Search

620 related items for PubMed ID: 26586529

  • 1. Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy.
    Xu CC, Denton KR, Wang ZB, Zhang X, Li XJ.
    Dis Model Mech; 2016 Jan; 9(1):39-49. PubMed ID: 26586529
    [Abstract] [Full Text] [Related]

  • 2. Established Stem Cell Model of Spinal Muscular Atrophy Is Applicable in the Evaluation of the Efficacy of Thyrotropin-Releasing Hormone Analog.
    Ohuchi K, Funato M, Kato Z, Seki J, Kawase C, Tamai Y, Ono Y, Nagahara Y, Noda Y, Kameyama T, Ando S, Tsuruma K, Shimazawa M, Hara H, Kaneko H.
    Stem Cells Transl Med; 2016 Feb; 5(2):152-63. PubMed ID: 26683872
    [Abstract] [Full Text] [Related]

  • 3. Recapitulation of spinal motor neuron-specific disease phenotypes in a human cell model of spinal muscular atrophy.
    Wang ZB, Zhang X, Li XJ.
    Cell Res; 2013 Mar; 23(3):378-93. PubMed ID: 23208423
    [Abstract] [Full Text] [Related]

  • 4. Modeling the differential phenotypes of spinal muscular atrophy with high-yield generation of motor neurons from human induced pluripotent stem cells.
    Lin X, Li JJ, Qian WJ, Zhang QJ, Wang ZF, Lu YQ, Dong EL, He J, Wang N, Ma LX, Chen WJ.
    Oncotarget; 2017 Jun 27; 8(26):42030-42042. PubMed ID: 28159932
    [Abstract] [Full Text] [Related]

  • 5. Edaravone is a candidate agent for spinal muscular atrophy: In vitro analysis using a human induced pluripotent stem cells-derived disease model.
    Ando S, Funato M, Ohuchi K, Kameyama T, Inagaki S, Seki J, Kawase C, Tsuruma K, Shimazawa M, Kaneko H, Hara H.
    Eur J Pharmacol; 2017 Nov 05; 814():161-168. PubMed ID: 28826912
    [Abstract] [Full Text] [Related]

  • 6. The Protective Effects of Levetiracetam on a Human iPSCs-Derived Spinal Muscular Atrophy Model.
    Ando S, Funato M, Ohuchi K, Inagaki S, Sato A, Seki J, Kawase C, Saito T, Nishio H, Nakamura S, Shimazawa M, Kaneko H, Hara H.
    Neurochem Res; 2019 Jul 05; 44(7):1773-1779. PubMed ID: 31102025
    [Abstract] [Full Text] [Related]

  • 7. Tissue-specific models of spinal muscular atrophy confirm a critical role of SMN in motor neurons from embryonic to adult stages.
    Laird AS, Mackovski N, Rinkwitz S, Becker TS, Giacomotto J.
    Hum Mol Genet; 2016 May 01; 25(9):1728-38. PubMed ID: 26908606
    [Abstract] [Full Text] [Related]

  • 8. SMN deficiency alters Nrxn2 expression and splicing in zebrafish and mouse models of spinal muscular atrophy.
    See K, Yadav P, Giegerich M, Cheong PS, Graf M, Vyas H, Lee SG, Mathavan S, Fischer U, Sendtner M, Winkler C.
    Hum Mol Genet; 2014 Apr 01; 23(7):1754-70. PubMed ID: 24218366
    [Abstract] [Full Text] [Related]

  • 9. The water extract of Liuwei dihuang possesses multi-protective properties on neurons and muscle tissue against deficiency of survival motor neuron protein.
    Tseng YT, Jong YJ, Liang WF, Chang FR, Lo YC.
    Phytomedicine; 2017 Oct 15; 34():97-105. PubMed ID: 28899515
    [Abstract] [Full Text] [Related]

  • 10. Spinal muscular atrophy patient-derived motor neurons exhibit hyperexcitability.
    Liu H, Lu J, Chen H, Du Z, Li XJ, Zhang SC.
    Sci Rep; 2015 Jul 20; 5():12189. PubMed ID: 26190808
    [Abstract] [Full Text] [Related]

  • 11. SMA Human iPSC-Derived Motor Neurons Show Perturbed Differentiation and Reduced miR-335-5p Expression.
    Murdocca M, Ciafrè SA, Spitalieri P, Talarico RV, Sanchez M, Novelli G, Sangiuolo F.
    Int J Mol Sci; 2016 Jul 30; 17(8):. PubMed ID: 27483257
    [Abstract] [Full Text] [Related]

  • 12. Spinal motor neuron loss occurs through a p53-and-p21-independent mechanism in the Smn2B/- mouse model of spinal muscular atrophy.
    Reedich EJ, Kalski M, Armijo N, Cox GA, DiDonato CJ.
    Exp Neurol; 2021 Mar 30; 337():113587. PubMed ID: 33382987
    [Abstract] [Full Text] [Related]

  • 13. Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models.
    de la Fuente S, Sansa A, Hidalgo I, Vivancos N, Romero-Guevara R, Garcera A, Soler RM.
    Cell Death Dis; 2020 Jun 25; 11(6):487. PubMed ID: 32587237
    [Abstract] [Full Text] [Related]

  • 14. Motor neuron mitochondrial dysfunction in spinal muscular atrophy.
    Miller N, Shi H, Zelikovich AS, Ma YC.
    Hum Mol Genet; 2016 Aug 15; 25(16):3395-3406. PubMed ID: 27488123
    [Abstract] [Full Text] [Related]

  • 15. Decreased Motor Neuron Support by SMA Astrocytes due to Diminished MCP1 Secretion.
    Martin JE, Nguyen TT, Grunseich C, Nofziger JH, Lee PR, Fields D, Fischbeck KH, Foran E.
    J Neurosci; 2017 May 24; 37(21):5309-5318. PubMed ID: 28450545
    [Abstract] [Full Text] [Related]

  • 16. A Perturbed MicroRNA Expression Pattern Characterizes Embryonic Neural Stem Cells Derived from a Severe Mouse Model of Spinal Muscular Atrophy (SMA).
    Luchetti A, Ciafrè SA, Murdocca M, Malgieri A, Masotti A, Sanchez M, Farace MG, Novelli G, Sangiuolo F.
    Int J Mol Sci; 2015 Aug 06; 16(8):18312-27. PubMed ID: 26258776
    [Abstract] [Full Text] [Related]

  • 17. A transgene carrying an A2G missense mutation in the SMN gene modulates phenotypic severity in mice with severe (type I) spinal muscular atrophy.
    Monani UR, Pastore MT, Gavrilina TO, Jablonka S, Le TT, Andreassi C, DiCocco JM, Lorson C, Androphy EJ, Sendtner M, Podell M, Burghes AH.
    J Cell Biol; 2003 Jan 06; 160(1):41-52. PubMed ID: 12515823
    [Abstract] [Full Text] [Related]

  • 18. Brief report: phenotypic rescue of induced pluripotent stem cell-derived motoneurons of a spinal muscular atrophy patient.
    Chang T, Zheng W, Tsark W, Bates S, Huang H, Lin RJ, Yee JK.
    Stem Cells; 2011 Dec 06; 29(12):2090-3. PubMed ID: 21956898
    [Abstract] [Full Text] [Related]

  • 19. Hypothermia improves disease manifestations in SMA mice via SMN augmentation.
    Tsai LK, Chen CL, Tsai YC, Ting CH, Chien YH, Lee NC, Hwu WL.
    Hum Mol Genet; 2016 Feb 15; 25(4):631-41. PubMed ID: 26647309
    [Abstract] [Full Text] [Related]

  • 20. Calpain Inhibition Increases SMN Protein in Spinal Cord Motoneurons and Ameliorates the Spinal Muscular Atrophy Phenotype in Mice.
    de la Fuente S, Sansa A, Periyakaruppiah A, Garcera A, Soler RM.
    Mol Neurobiol; 2019 Jun 15; 56(6):4414-4427. PubMed ID: 30327977
    [Abstract] [Full Text] [Related]

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