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1257 related items for PubMed ID: 26588065

  • 1. Synthesis, pharmacological assessment, molecular modeling and in silico studies of fused tricyclic coumarin derivatives as a new family of multifunctional anti-Alzheimer agents.
    Shaik JB, Palaka BK, Penumala M, Kotapati KV, Devineni SR, Eadlapalli S, Darla MM, Ampasala DR, Vadde R, Amooru GD.
    Eur J Med Chem; 2016 Jan 01; 107():219-32. PubMed ID: 26588065
    [Abstract] [Full Text] [Related]

  • 2. Synthesis, biological evaluation and molecular modeling study of novel tacrine-carbazole hybrids as potential multifunctional agents for the treatment of Alzheimer's disease.
    Thiratmatrakul S, Yenjai C, Waiwut P, Vajragupta O, Reubroycharoen P, Tohda M, Boonyarat C.
    Eur J Med Chem; 2014 Mar 21; 75():21-30. PubMed ID: 24508831
    [Abstract] [Full Text] [Related]

  • 3. 3-Aryl Coumarin Derivatives Bearing Aminoalkoxy Moiety as Multi-Target-Directed Ligands against Alzheimer's Disease.
    Abdshahzadeh H, Golshani M, Nadri H, Saberi Kia I, Abdolahi Z, Forootanfar H, Ameri A, Tüylü Küçükkılınç T, Ayazgok B, Jalili-Baleh L, Sadat Ebrahimi SE, Moghimi S, Haririan I, Khoobi M, Foroumadi A.
    Chem Biodivers; 2019 May 21; 16(5):e1800436. PubMed ID: 30957958
    [Abstract] [Full Text] [Related]

  • 4. Synthesis, biological assessment, and molecular modeling of racemic 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amines as potential drugs for the treatment of Alzheimer's disease.
    Maalej E, Chabchoub F, Oset-Gasque MJ, Esquivias-Pérez M, González MP, Monjas L, Pérez C, de los Ríos C, Rodríguez-Franco MI, Iriepa I, Moraleda I, Chioua M, Romero A, Marco-Contelles J, Samadi A.
    Eur J Med Chem; 2012 Aug 21; 54():750-63. PubMed ID: 22795665
    [Abstract] [Full Text] [Related]

  • 5. Development of cyanopyridine-triazine hybrids as lead multitarget anti-Alzheimer agents.
    Maqbool M, Manral A, Jameel E, Kumar J, Saini V, Shandilya A, Tiwari M, Hoda N, Jayaram B.
    Bioorg Med Chem; 2016 Jun 15; 24(12):2777-88. PubMed ID: 27157006
    [Abstract] [Full Text] [Related]

  • 6. Design and synthesis of novel coumarin derivatives as potential acetylcholinesterase inhibitors for Alzheimer's disease.
    Amin KM, Abdel Rahman DE, Abdelrasheed Allam H, El-Zoheiry HH.
    Bioorg Chem; 2021 May 15; 110():104792. PubMed ID: 33799178
    [Abstract] [Full Text] [Related]

  • 7. Multifunctional novel Diallyl disulfide (DADS) derivatives with β-amyloid-reducing, cholinergic, antioxidant and metal chelating properties for the treatment of Alzheimer's disease.
    Manral A, Saini V, Meena P, Tiwari M.
    Bioorg Med Chem; 2015 Oct 01; 23(19):6389-403. PubMed ID: 26337018
    [Abstract] [Full Text] [Related]

  • 8. Synthesis, antioxidant and anticholinesterase activities of novel coumarylthiazole derivatives.
    Kurt BZ, Gazioglu I, Sonmez F, Kucukislamoglu M.
    Bioorg Chem; 2015 Apr 01; 59():80-90. PubMed ID: 25706320
    [Abstract] [Full Text] [Related]

  • 9. Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles.
    Samadi A, Marco-Contelles J, Soriano E, Alvarez-Pérez M, Chioua M, Romero A, González-Lafuente L, Gandía L, Roda JM, López MG, Villarroya M, García AG, Ríos Cde L.
    Bioorg Med Chem; 2010 Aug 15; 18(16):5861-72. PubMed ID: 20656495
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, Biological Evaluation, and Molecular Docking of 8-imino-2-oxo-2H,8H-pyrano[2,3-f]chromene Analogs: New Dual AChE Inhibitors as Potential Drugs for the Treatment of Alzheimer's Disease.
    Shaik JB, Palaka BK, Penumala M, Eadlapalli S, Darla Mark M, Ampasala DR, Vadde R, Amooru Gangaiah D.
    Chem Biol Drug Des; 2016 Jul 15; 88(1):43-53. PubMed ID: 26833890
    [Abstract] [Full Text] [Related]

  • 11. Bis-Amiridines as Acetylcholinesterase and Butyrylcholinesterase Inhibitors: N-Functionalization Determines the Multitarget Anti-Alzheimer's Activity Profile.
    Makhaeva GF, Kovaleva NV, Boltneva NP, Rudakova EV, Lushchekina SV, Astakhova TY, Serkov IV, Proshin AN, Radchenko EV, Palyulin VA, Korabecny J, Soukup O, Bachurin SO, Richardson RJ.
    Molecules; 2022 Feb 04; 27(3):. PubMed ID: 35164325
    [Abstract] [Full Text] [Related]

  • 12. Phytochemical profiling and in vitro screening for anticholinesterase, antioxidant, antiglucosidase and neuroprotective effect of three traditional medicinal plants for Alzheimer's Disease and Diabetes Mellitus dual therapy.
    Penumala M, Zinka RB, Shaik JB, Mallepalli SKR, Vadde R, Amooru DG.
    BMC Complement Altern Med; 2018 Mar 02; 18(1):77. PubMed ID: 29499679
    [Abstract] [Full Text] [Related]

  • 13. Amiridine-piperazine hybrids as cholinesterase inhibitors and potential multitarget agents for Alzheimer's disease treatment.
    Makhaeva GF, Lushchekina SV, Kovaleva NV, Yu Astakhova T, Boltneva NP, Rudakova EV, Serebryakova OG, Proshin AN, Serkov IV, Trofimova TP, Tafeenko VA, Radchenko EV, Palyulin VA, Fisenko VP, Korábečný J, Soukup O, Richardson RJ.
    Bioorg Chem; 2021 Jul 02; 112():104974. PubMed ID: 34029971
    [Abstract] [Full Text] [Related]

  • 14. Design, synthesis and biological activity of novel donepezil derivatives bearing N-benzyl pyridinium moiety as potent and dual binding site acetylcholinesterase inhibitors.
    Lan JS, Zhang T, Liu Y, Yang J, Xie SS, Liu J, Miao ZY, Ding Y.
    Eur J Med Chem; 2017 Jun 16; 133():184-196. PubMed ID: 28388521
    [Abstract] [Full Text] [Related]

  • 15. Design, synthesis and evaluation of novel tacrine-(β-carboline) hybrids as multifunctional agents for the treatment of Alzheimer's disease.
    Lan JS, Xie SS, Li SY, Pan LF, Wang XB, Kong LY.
    Bioorg Med Chem; 2014 Nov 01; 22(21):6089-104. PubMed ID: 25282654
    [Abstract] [Full Text] [Related]

  • 16. Synthesis and evaluation of 7-substituted coumarin derivatives as multimodal monoamine oxidase-B and cholinesterase inhibitors for the treatment of Alzheimer's disease.
    Joubert J, Foka GB, Repsold BP, Oliver DW, Kapp E, Malan SF.
    Eur J Med Chem; 2017 Jan 05; 125():853-864. PubMed ID: 27744252
    [Abstract] [Full Text] [Related]

  • 17. Novel thiophene Chalcones-Coumarin as acetylcholinesterase inhibitors: Design, synthesis, biological evaluation, molecular docking, ADMET prediction and molecular dynamics simulation.
    Hasan AH, Murugesan S, Amran SI, Chander S, Alanazi MM, Hadda TB, Shakya S, Pratama MRF, Das B, Biswas S, Jamalis J.
    Bioorg Chem; 2022 Feb 05; 119():105572. PubMed ID: 34971946
    [Abstract] [Full Text] [Related]

  • 18. Novel tacrine-based acetylcholinesterase inhibitors as potential agents for the treatment of Alzheimer's disease: Quinolotacrine hybrids.
    Sadafi Kohnehshahri M, Chehardoli G, Bahiraei M, Akbarzadeh T, Ranjbar A, Rastegari A, Najafi Z.
    Mol Divers; 2022 Feb 05; 26(1):489-503. PubMed ID: 34491490
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and evaluation of 4-substituted coumarins as novel acetylcholinesterase inhibitors.
    Razavi SF, Khoobi M, Nadri H, Sakhteman A, Moradi A, Emami S, Foroumadi A, Shafiee A.
    Eur J Med Chem; 2013 Jun 05; 64():252-9. PubMed ID: 23644208
    [Abstract] [Full Text] [Related]

  • 20. Evaluation of Anti-Alzheimer Activity of Synthetic Coumarins by Combination of in Vitro and in Silico Approaches.
    Erdogan Orhan I, Deniz FSS, Salmas RE, Irmak S, Acar OO, Turgut GC, Sen A, Zbancioc AM, Luca SV, Skiba A, Skalicka-Woźniak K, Tataringa G.
    Chem Biodivers; 2022 Dec 05; 19(12):e202200315. PubMed ID: 36282001
    [Abstract] [Full Text] [Related]

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