These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
24. Comparison of inhibition potentials of drugs against zidovudine glucuronidation in rat hepatocytes and liver microsomes. Mano Y, Usui T, Kamimura H. Drug Metab Dispos; 2007 Apr; 35(4):602-6. PubMed ID: 17267620 [Abstract] [Full Text] [Related]
25. Metabolic activation of TM5441 in vitro and in vivo: Formation of reactive metabolites and human enzymes involved. Lang SQ, Lang WH, Yu HY, Wang L. Eur J Pharm Sci; 2020 Feb 15; 143():105195. PubMed ID: 31852629 [Abstract] [Full Text] [Related]
26. Development of an in vitro screening model for the biosynthesis of acyl glucuronide metabolites and the assessment of their reactivity toward human serum albumin. Bolze S, Bromet N, Gay-Feutry C, Massiere F, Boulieu R, Hulot T. Drug Metab Dispos; 2002 Apr 15; 30(4):404-13. PubMed ID: 11901094 [Abstract] [Full Text] [Related]
30. Roles of human hepatic cytochrome P450s 2C9 and 3A4 in the metabolic activation of diclofenac. Tang W, Stearns RA, Wang RW, Chiu SH, Baillie TA. Chem Res Toxicol; 1999 Feb 15; 12(2):192-9. PubMed ID: 10027798 [Abstract] [Full Text] [Related]
34. Bioactivation of flutamide metabolites by human liver microsomes. Kang P, Dalvie D, Smith E, Zhou S, Deese A, Nieman JA. Drug Metab Dispos; 2008 Jul 15; 36(7):1425-37. PubMed ID: 18411402 [Abstract] [Full Text] [Related]
35. A novel trapping system for the detection of reactive drug metabolites using the fungus Cunninghamella elegans and high resolution mass spectrometry. Rydevik A, Hansson A, Hellqvist A, Bondesson U, Hedeland M. Drug Test Anal; 2015 Jul 15; 7(7):626-33. PubMed ID: 25209992 [Abstract] [Full Text] [Related]
36. Studies on cytochrome P-450-mediated bioactivation of diclofenac in rats and in human hepatocytes: identification of glutathione conjugated metabolites. Tang W, Stearns RA, Bandiera SM, Zhang Y, Raab C, Braun MP, Dean DC, Pang J, Leung KH, Doss GA, Strauss JR, Kwei GY, Rushmore TH, Chiu SH, Baillie TA. Drug Metab Dispos; 1999 Mar 15; 27(3):365-72. PubMed ID: 10064567 [Abstract] [Full Text] [Related]
37. Identification of a novel glutathione adduct of diclofenac, 4'-hydroxy-2'-glutathion-deschloro-diclofenac, upon incubation with human liver microsomes. Yu LJ, Chen Y, Deninno MP, O'Connell TN, Hop CE. Drug Metab Dispos; 2005 Apr 15; 33(4):484-8. PubMed ID: 15640374 [Abstract] [Full Text] [Related]
38. Bioactivation of phencyclidine in rat and human liver microsomes and recombinant P450 2B enzymes: evidence for the formation of a novel quinone methide intermediate. Driscoll JP, Kornecki K, Wolkowski JP, Chupak L, Kalgutkar AS, O'Donnell JP. Chem Res Toxicol; 2007 Oct 15; 20(10):1488-97. PubMed ID: 17892269 [Abstract] [Full Text] [Related]