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Journal Abstract Search

438 related items for PubMed ID: 2665964

  • 1. Genotoxicity of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): formation of 2-hydroxamino-PhIP, a directly acting genotoxic metabolite.
    Holme JA, Wallin H, Brunborg G, Søderlund EJ, Hongslo JK, Alexander J.
    Carcinogenesis; 1989 Aug; 10(8):1389-96. PubMed ID: 2665964
    [Abstract] [Full Text] [Related]

  • 2. Genotoxic activity of the N-acetylated metabolites of the food mutagens 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ).
    Brunborg G, Holme JA, Alexander J, Becher G, Hongslo JK.
    Mutagenesis; 1988 Jul; 3(4):303-9. PubMed ID: 3062317
    [Abstract] [Full Text] [Related]

  • 3. Comparative genotoxic effects of IQ and MeIQ in Salmonella typhimurium and cultured mammalian cells.
    Holme JA, Hongslo JK, Søderlund E, Brunborg G, Christensen T, Alexander J, Dybing E.
    Mutat Res; 1987 Apr; 187(4):181-90. PubMed ID: 3550445
    [Abstract] [Full Text] [Related]

  • 4. Metabolic formation, synthesis and genotoxicity of the N-hydroxy derivative of the food mutagen 2-amino-1-methyl-6-phenylimidazo (4,5-b) pyridine (PhIP).
    Frandsen H, Rasmussen ES, Nielsen PA, Farmer P, Dragsted L, Larsen JC.
    Mutagenesis; 1991 Jan; 6(1):93-8. PubMed ID: 1903830
    [Abstract] [Full Text] [Related]

  • 5. 4-(2-amino-1-methylimidazo[4,5-b]pyrid-6-yl)phenyl sulfate--a major metabolite of the food mutagen 2-amino-1-methyl-6- phenylimidazo[4,5-b]pyridine (PhIP) in the rat.
    Alexander J, Wallin H, Holme JA, Becher G.
    Carcinogenesis; 1989 Aug; 10(8):1543-7. PubMed ID: 2752529
    [Abstract] [Full Text] [Related]

  • 6. Formation of a glutathione conjugate and a semistable transportable glucuronide conjugate of N2-oxidized species of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in rat liver.
    Alexander J, Wallin H, Rossland OJ, Solberg KE, Holme JA, Becher G, Andersson R, Grivas S.
    Carcinogenesis; 1991 Dec; 12(12):2239-45. PubMed ID: 1747923
    [Abstract] [Full Text] [Related]

  • 7. The role of sulfation and/or acetylation in the metabolism of the cooked-food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Salmonella typhimurium and isolated rat hepatocytes.
    Malfatti MA, Buonarati MH, Turteltaub KW, Shen NH, Felton JS.
    Chem Res Toxicol; 1994 Dec; 7(2):139-47. PubMed ID: 8199301
    [Abstract] [Full Text] [Related]

  • 8. Differential rates of metabolic activation and detoxication of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by different cytochrome P450 enzymes.
    Wallin H, Mikalsen A, Guengerich FP, Ingelman-Sundberg M, Solberg KE, Rossland OJ, Alexander J.
    Carcinogenesis; 1990 Mar; 11(3):489-92. PubMed ID: 2311193
    [Abstract] [Full Text] [Related]

  • 9. Co-culture systems for assessing the stability and genotoxicity of reactive 1,2-dibromo-3-chloropropane (DBCP) metabolites.
    Søderlund EJ, Brunborg G, Holme JA, Hongslo JK, Nelson SD, Dybing E.
    Mutagenesis; 1991 Jan; 6(1):25-30. PubMed ID: 2038269
    [Abstract] [Full Text] [Related]

  • 10. Modulation of the mutagenic effects of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and 2-amino-3,4-dimethylimidazo[4,5-f]quinoline (MeIQ) in bacteria with rat-liver 9000 x g supernatant or monolayers of rat hepatocytes as an activation system.
    Holme JA, Brunborg G, Alexander J, Trygg B, Bjørnstad C.
    Mutat Res; 1988 Jan; 197(1):39-49. PubMed ID: 3275882
    [Abstract] [Full Text] [Related]

  • 11. Azido- and nitro-PhIP, relatives of the heterocyclic arylamine and food mutagen PhIP--mechanism of their mutagenicity in Salmonella.
    Wild D, Watkins BE, Vanderlaan M.
    Carcinogenesis; 1991 Jun; 12(6):1091-6. PubMed ID: 2044190
    [Abstract] [Full Text] [Related]

  • 12. The metabolism and DNA binding of the cooked-food mutagen, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in precision-cut rat liver slices.
    Connors MS, Malfatti MA, Felton JS.
    Chem Biol Interact; 1995 May 19; 96(2):185-202. PubMed ID: 7728907
    [Abstract] [Full Text] [Related]

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  • 17. Activation of the food mutagens IQ and MeIQ by hepatic S9 fractions derived from various species.
    Alldrick AJ, Rowland IR.
    Mutat Res; 1985 Oct 19; 144(2):59-62. PubMed ID: 3900706
    [Abstract] [Full Text] [Related]

  • 18. Activation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) to mutagenic metabolites.
    Buonarati MH, Felton JS.
    Carcinogenesis; 1990 Jul 19; 11(7):1133-8. PubMed ID: 2197012
    [Abstract] [Full Text] [Related]

  • 19. Mutagenic activation of 3-amino-1,4-dimethyl-5H-pyrido(4,3-b)indole(Trp-P-1) and 3-amino-1-methyl-5H-pyrido(4,3-b)indole (Trp-P-2) by primary cultures of adult rat hepatocytes: effect of Aroclor induction in vitro.
    Decloître F, Hamon G, Martin M, Thybaud-Lambay V.
    Mutat Res; 1984 Jul 19; 137(2-3):123-32. PubMed ID: 6433191
    [Abstract] [Full Text] [Related]

  • 20. Activation of amino-alpha-carboline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a copper phthalocyanine cellulose extract of cigarette smoke condensate by cytochrome P-450 enzymes in rat and human liver microsomes.
    Shimada T, Guengerich FP.
    Cancer Res; 1991 Oct 01; 51(19):5284-91. PubMed ID: 1913651
    [Abstract] [Full Text] [Related]

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