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Journal Abstract Search


493 related items for PubMed ID: 26678016

  • 1. Attenuated presenilin-1 endoproteolysis enhances store-operated calcium currents in neuronal cells.
    Ryazantseva M, Skobeleva K, Glushankova L, Kaznacheyeva E.
    J Neurochem; 2016 Mar; 136(5):1085-95. PubMed ID: 26678016
    [Abstract] [Full Text] [Related]

  • 2. Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease.
    Honarnejad K, Jung CK, Lammich S, Arzberger T, Kretzschmar H, Herms J.
    J Cell Mol Med; 2013 Feb; 17(2):293-302. PubMed ID: 23379308
    [Abstract] [Full Text] [Related]

  • 3. G206D Mutation of Presenilin-1 Reduces Pen2 Interaction, Increases Aβ42/Aβ40 Ratio and Elevates ER Ca(2+) Accumulation.
    Chen WT, Hsieh YF, Huang YJ, Lin CC, Lin YT, Liu YC, Lien CC, Cheng IH.
    Mol Neurobiol; 2015 Dec; 52(3):1835-1849. PubMed ID: 25394380
    [Abstract] [Full Text] [Related]

  • 4. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels.
    Zatti G, Burgo A, Giacomello M, Barbiero L, Ghidoni R, Sinigaglia G, Florean C, Bagnoli S, Binetti G, Sorbi S, Pizzo P, Fasolato C.
    Cell Calcium; 2006 Jun; 39(6):539-50. PubMed ID: 16620965
    [Abstract] [Full Text] [Related]

  • 5. Familial Alzheimer's disease-associated presenilin 1 mutants promote γ-secretase cleavage of STIM1 to impair store-operated Ca2+ entry.
    Tong BC, Lee CS, Cheng WH, Lai KO, Foskett JK, Cheung KH.
    Sci Signal; 2016 Sep 06; 9(444):ra89. PubMed ID: 27601731
    [Abstract] [Full Text] [Related]

  • 6. Presenilin-1 Delta E9 Mutant Induces STIM1-Driven Store-Operated Calcium Channel Hyperactivation in Hippocampal Neurons.
    Ryazantseva M, Goncharova A, Skobeleva K, Erokhin M, Methner A, Georgiev P, Kaznacheyeva E.
    Mol Neurobiol; 2018 Jun 06; 55(6):4667-4680. PubMed ID: 28707074
    [Abstract] [Full Text] [Related]

  • 7. Three-amino acid spacing of presenilin endoproteolysis suggests a general stepwise cleavage of gamma-secretase-mediated intramembrane proteolysis.
    Fukumori A, Fluhrer R, Steiner H, Haass C.
    J Neurosci; 2010 Jun 09; 30(23):7853-62. PubMed ID: 20534834
    [Abstract] [Full Text] [Related]

  • 8. Thapsigargin affects presenilin-2 but not presenilin-1 regulation in SK-N-BE cells.
    Rivabene R, Visentin S, Piscopo P, De Nuccio C, Crestini A, Svetoni F, Rosa P, Confaloni A.
    Exp Biol Med (Maywood); 2014 Feb 09; 239(2):213-24. PubMed ID: 24363250
    [Abstract] [Full Text] [Related]

  • 9. Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations.
    Tu H, Nelson O, Bezprozvanny A, Wang Z, Lee SF, Hao YH, Serneels L, De Strooper B, Yu G, Bezprozvanny I.
    Cell; 2006 Sep 08; 126(5):981-93. PubMed ID: 16959576
    [Abstract] [Full Text] [Related]

  • 10. Presenilin Is Essential for ApoE Secretion, a Novel Role of Presenilin Involved in Alzheimer's Disease Pathogenesis.
    Islam S, Sun Y, Gao Y, Nakamura T, Noorani AA, Li T, Wong PC, Kimura N, Matsubara E, Kasuga K, Ikeuchi T, Tomita T, Zou K, Michikawa M.
    J Neurosci; 2022 Feb 23; 42(8):1574-1586. PubMed ID: 34987110
    [Abstract] [Full Text] [Related]

  • 11. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W, Zhang J, Ostaszewski BL, Kimberly WT, Seubert P, Koo EH, Shen J, Selkoe DJ.
    Biochemistry; 1998 Nov 24; 37(47):16465-71. PubMed ID: 9843412
    [Abstract] [Full Text] [Related]

  • 12. Familial Alzheimer's disease-linked presenilin-1 mutation M146V affects store-operated calcium entry: does gain look like loss?
    Ryazantseva M, Skobeleva K, Kaznacheyeva E.
    Biochimie; 2013 Jul 24; 95(7):1506-9. PubMed ID: 23624206
    [Abstract] [Full Text] [Related]

  • 13. Different transmembrane domains determine the specificity and efficiency of the cleavage activity of the γ-secretase subunit presenilin.
    Schmidt FC, Fitz K, Feilen LP, Okochi M, Steiner H, Langosch D.
    J Biol Chem; 2023 May 24; 299(5):104626. PubMed ID: 36944398
    [Abstract] [Full Text] [Related]

  • 14. Conformational Models of APP Processing by Gamma Secretase Based on Analysis of Pathogenic Mutations.
    Kim M, Bezprozvanny I.
    Int J Mol Sci; 2021 Dec 18; 22(24):. PubMed ID: 34948396
    [Abstract] [Full Text] [Related]

  • 15. Intracellular Calcium Dysregulation by the Alzheimer's Disease-Linked Protein Presenilin 2.
    Galla L, Redolfi N, Pozzan T, Pizzo P, Greotti E.
    Int J Mol Sci; 2020 Jan 24; 21(3):. PubMed ID: 31991578
    [Abstract] [Full Text] [Related]

  • 16. Repression of transcription of presenilin-1 inhibits γ-secretase independent ER Ca²⁺ leak that is impaired by FAD mutations.
    Das HK, Tchedre K, Mueller B.
    J Neurochem; 2012 Aug 24; 122(3):487-500. PubMed ID: 22607268
    [Abstract] [Full Text] [Related]

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  • 18. Pathological activity of familial Alzheimer's disease-associated mutant presenilin can be executed by six different gamma-secretase complexes.
    Shirotani K, Tomioka M, Kremmer E, Haass C, Steiner H.
    Neurobiol Dis; 2007 Jul 24; 27(1):102-7. PubMed ID: 17560791
    [Abstract] [Full Text] [Related]

  • 19. Is Alzheimer's disease a disorder of mitochondria-associated membranes?
    Schon EA, Area-Gomez E.
    J Alzheimers Dis; 2010 Jul 24; 20 Suppl 2():S281-92. PubMed ID: 20421691
    [Abstract] [Full Text] [Related]

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