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Journal Abstract Search

1449 related items for PubMed ID: 26683872

  • 1. Established Stem Cell Model of Spinal Muscular Atrophy Is Applicable in the Evaluation of the Efficacy of Thyrotropin-Releasing Hormone Analog.
    Ohuchi K, Funato M, Kato Z, Seki J, Kawase C, Tamai Y, Ono Y, Nagahara Y, Noda Y, Kameyama T, Ando S, Tsuruma K, Shimazawa M, Hara H, Kaneko H.
    Stem Cells Transl Med; 2016 Feb; 5(2):152-63. PubMed ID: 26683872
    [Abstract] [Full Text] [Related]

  • 2. Edaravone is a candidate agent for spinal muscular atrophy: In vitro analysis using a human induced pluripotent stem cells-derived disease model.
    Ando S, Funato M, Ohuchi K, Kameyama T, Inagaki S, Seki J, Kawase C, Tsuruma K, Shimazawa M, Kaneko H, Hara H.
    Eur J Pharmacol; 2017 Nov 05; 814():161-168. PubMed ID: 28826912
    [Abstract] [Full Text] [Related]

  • 3. Modeling the differential phenotypes of spinal muscular atrophy with high-yield generation of motor neurons from human induced pluripotent stem cells.
    Lin X, Li JJ, Qian WJ, Zhang QJ, Wang ZF, Lu YQ, Dong EL, He J, Wang N, Ma LX, Chen WJ.
    Oncotarget; 2017 Jun 27; 8(26):42030-42042. PubMed ID: 28159932
    [Abstract] [Full Text] [Related]

  • 4. Chronic treatment with lithium does not improve neuromuscular phenotype in a mouse model of severe spinal muscular atrophy.
    Dachs E, Piedrafita L, Hereu M, Esquerda JE, Calderó J.
    Neuroscience; 2013 Oct 10; 250():417-33. PubMed ID: 23876328
    [Abstract] [Full Text] [Related]

  • 5. Cell cycle inhibitors protect motor neurons in an organoid model of Spinal Muscular Atrophy.
    Hor JH, Soh ES, Tan LY, Lim VJW, Santosa MM, Winanto, Ho BX, Fan Y, Soh BS, Ng SY.
    Cell Death Dis; 2018 Oct 27; 9(11):1100. PubMed ID: 30368521
    [Abstract] [Full Text] [Related]

  • 6. Pharmacologically induced mouse model of adult spinal muscular atrophy to evaluate effectiveness of therapeutics after disease onset.
    Feng Z, Ling KK, Zhao X, Zhou C, Karp G, Welch EM, Naryshkin N, Ratni H, Chen KS, Metzger F, Paushkin S, Weetall M, Ko CP.
    Hum Mol Genet; 2016 Mar 01; 25(5):964-75. PubMed ID: 26758873
    [Abstract] [Full Text] [Related]

  • 7. Astrocyte-produced miR-146a as a mediator of motor neuron loss in spinal muscular atrophy.
    Sison SL, Patitucci TN, Seminary ER, Villalon E, Lorson CL, Ebert AD.
    Hum Mol Genet; 2017 Sep 01; 26(17):3409-3420. PubMed ID: 28637335
    [Abstract] [Full Text] [Related]

  • 8. Seamless Genetic Conversion of SMN2 to SMN1 via CRISPR/Cpf1 and Single-Stranded Oligodeoxynucleotides in Spinal Muscular Atrophy Patient-Specific Induced Pluripotent Stem Cells.
    Zhou M, Hu Z, Qiu L, Zhou T, Feng M, Hu Q, Zeng B, Li Z, Sun Q, Wu Y, Liu X, Wu L, Liang D.
    Hum Gene Ther; 2018 Nov 01; 29(11):1252-1263. PubMed ID: 29598153
    [Abstract] [Full Text] [Related]

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  • 11. Notch Signaling Mediates Astrocyte Abnormality in Spinal Muscular Atrophy Model Systems.
    Ohuchi K, Funato M, Yoshino Y, Ando S, Inagaki S, Sato A, Kawase C, Seki J, Saito T, Nishio H, Nakamura S, Shimazawa M, Kaneko H, Hara H.
    Sci Rep; 2019 Mar 06; 9(1):3701. PubMed ID: 30842449
    [Abstract] [Full Text] [Related]

  • 12. A screen for regulators of survival of motor neuron protein levels.
    Makhortova NR, Hayhurst M, Cerqueira A, Sinor-Anderson AD, Zhao WN, Heiser PW, Arvanites AC, Davidow LS, Waldon ZO, Steen JA, Lam K, Ngo HD, Rubin LL.
    Nat Chem Biol; 2011 Jun 19; 7(8):544-52. PubMed ID: 21685895
    [Abstract] [Full Text] [Related]

  • 13. A SMN2 Splicing Modifier Rescues the Disease Phenotypes in an In Vitro Human Spinal Muscular Atrophy Model.
    Son YS, Choi K, Lee H, Kwon O, Jung KB, Cho S, Baek J, Son B, Kang SM, Kang M, Yoon J, Shen H, Lee S, Oh JH, Lee HA, Lee MO, Cho HS, Jung CR, Kim J, Cho S, Son MY.
    Stem Cells Dev; 2019 Apr 01; 28(7):438-453. PubMed ID: 30667343
    [Abstract] [Full Text] [Related]

  • 14. Spinal muscular atrophy phenotype is ameliorated in human motor neurons by SMN increase via different novel RNA therapeutic approaches.
    Nizzardo M, Simone C, Dametti S, Salani S, Ulzi G, Pagliarani S, Rizzo F, Frattini E, Pagani F, Bresolin N, Comi G, Corti S.
    Sci Rep; 2015 Jun 30; 5():11746. PubMed ID: 26123042
    [Abstract] [Full Text] [Related]

  • 15. Abnormal mitochondrial transport and morphology as early pathological changes in human models of spinal muscular atrophy.
    Xu CC, Denton KR, Wang ZB, Zhang X, Li XJ.
    Dis Model Mech; 2016 Jan 30; 9(1):39-49. PubMed ID: 26586529
    [Abstract] [Full Text] [Related]

  • 16. SAHA ameliorates the SMA phenotype in two mouse models for spinal muscular atrophy.
    Riessland M, Ackermann B, Förster A, Jakubik M, Hauke J, Garbes L, Fritzsche I, Mende Y, Blumcke I, Hahnen E, Wirth B.
    Hum Mol Genet; 2010 Apr 15; 19(8):1492-506. PubMed ID: 20097677
    [Abstract] [Full Text] [Related]

  • 17. The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy.
    d'Ydewalle C, Ramos DM, Pyles NJ, Ng SY, Gorz M, Pilato CM, Ling K, Kong L, Ward AJ, Rubin LL, Rigo F, Bennett CF, Sumner CJ.
    Neuron; 2017 Jan 04; 93(1):66-79. PubMed ID: 28017471
    [Abstract] [Full Text] [Related]

  • 18. Normalization of Patient-Identified Plasma Biomarkers in SMNΔ7 Mice following Postnatal SMN Restoration.
    Arnold WD, Duque S, Iyer CC, Zaworski P, McGovern VL, Taylor SJ, von Herrmann KM, Kobayashi DT, Chen KS, Kolb SJ, Paushkin SV, Burghes AH.
    PLoS One; 2016 Jan 04; 11(12):e0167077. PubMed ID: 27907033
    [Abstract] [Full Text] [Related]

  • 19. ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy.
    Kannan A, Jiang X, He L, Ahmad S, Gangwani L.
    Brain; 2020 Jan 01; 143(1):69-93. PubMed ID: 31828288
    [Abstract] [Full Text] [Related]

  • 20. Astrocytes influence the severity of spinal muscular atrophy.
    Rindt H, Feng Z, Mazzasette C, Glascock JJ, Valdivia D, Pyles N, Crawford TO, Swoboda KJ, Patitucci TN, Ebert AD, Sumner CJ, Ko CP, Lorson CL.
    Hum Mol Genet; 2015 Jul 15; 24(14):4094-102. PubMed ID: 25911676
    [Abstract] [Full Text] [Related]

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