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Journal Abstract Search


293 related items for PubMed ID: 26721623

  • 1. AT-101 simultaneously triggers apoptosis and a cytoprotective type of autophagy irrespective of expression levels and the subcellular localization of Bcl-xL and Bcl-2 in MCF7 cells.
    Antonietti P, Gessler F, Düssmann H, Reimertz C, Mittelbronn M, Prehn JH, Kögel D.
    Biochim Biophys Acta; 2016 Apr; 1863(4):499-509. PubMed ID: 26721623
    [Abstract] [Full Text] [Related]

  • 2. Chemoresistance is associated with increased cytoprotective autophagy and diminished apoptosis in bladder cancer cells treated with the BH3 mimetic (-)-Gossypol (AT-101).
    Mani J, Vallo S, Rakel S, Antonietti P, Gessler F, Blaheta R, Bartsch G, Michaelis M, Cinatl J, Haferkamp A, Kögel D.
    BMC Cancer; 2015 Apr 07; 15():224. PubMed ID: 25885284
    [Abstract] [Full Text] [Related]

  • 3. Autophagy inhibition enhances pan-Bcl-2 inhibitor AT-101-induced apoptosis in non-small cell lung cancer.
    Mei H, Lin Z, Wang Y, Wu G, Song Y.
    Neoplasma; 2014 Apr 07; 61(2):186-92. PubMed ID: 24299314
    [Abstract] [Full Text] [Related]

  • 4. The pan-Bcl-2 inhibitor (-)-gossypol triggers autophagic cell death in malignant glioma.
    Voss V, Senft C, Lang V, Ronellenfitsch MW, Steinbach JP, Seifert V, Kögel D.
    Mol Cancer Res; 2010 Jul 07; 8(7):1002-16. PubMed ID: 20587533
    [Abstract] [Full Text] [Related]

  • 5. Bcl-XL is qualitatively different from and ten times more effective than Bcl-2 when expressed in a breast cancer cell line.
    Fiebig AA, Zhu W, Hollerbach C, Leber B, Andrews DW.
    BMC Cancer; 2006 Aug 23; 6():213. PubMed ID: 16928273
    [Abstract] [Full Text] [Related]

  • 6. NF-κB activation fails to protect cells to TNFα-induced apoptosis in the absence of Bcl-xL, but not Mcl-1, Bcl-2 or Bcl-w.
    Casanelles E, Gozzelino R, Marqués-Fernández F, Iglesias-Guimarais V, Garcia-Belinchón M, Sánchez-Osuna M, Solé C, Moubarak RS, Comella JX, Yuste VJ.
    Biochim Biophys Acta; 2013 May 23; 1833(5):1085-95. PubMed ID: 23369735
    [Abstract] [Full Text] [Related]

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  • 8. A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2-Beclin1 interaction at endoplasmic reticulum.
    Lian J, Wu X, He F, Karnak D, Tang W, Meng Y, Xiang D, Ji M, Lawrence TS, Xu L.
    Cell Death Differ; 2011 Jan 23; 18(1):60-71. PubMed ID: 20577262
    [Abstract] [Full Text] [Related]

  • 9. Differential effect of anti-apoptotic genes Bcl-xL and c-FLIP on sensitivity of MCF-7 breast cancer cells to paclitaxel and docetaxel.
    Wang Z, Goulet R, Stanton KJ, Sadaria M, Nakshatri H.
    Anticancer Res; 2005 Jan 23; 25(3c):2367-79. PubMed ID: 16080463
    [Abstract] [Full Text] [Related]

  • 10. Induction of apoptosis and antitumor effects of a small molecule inhibitor of Bcl-2 and Bcl-xl, gossypol acetate, in multiple myeloma in vitro and in vivo.
    Lin J, Wu Y, Yang D, Zhao Y.
    Oncol Rep; 2013 Aug 23; 30(2):731-8. PubMed ID: 23708869
    [Abstract] [Full Text] [Related]

  • 11. Bcl2L12 with a BH3-like domain in regulating apoptosis and TMZ-induced autophagy: a prospective combination of ABT-737 and TMZ for treating glioma.
    Yang MC, Loh JK, Li YY, Huang WS, Chou CH, Cheng JT, Wang YT, Lieu AS, Howng SL, Hong YR, Chou AK.
    Int J Oncol; 2015 Mar 23; 46(3):1304-16. PubMed ID: 25586056
    [Abstract] [Full Text] [Related]

  • 12. Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic Resistance.
    Pécot J, Maillet L, Le Pen J, Vuillier C, Trécesson SC, Fétiveau A, Sarosiek KA, Bock FJ, Braun F, Letai A, Tait SWG, Gautier F, Juin PP.
    Cell Rep; 2016 Dec 20; 17(12):3347-3358. PubMed ID: 28009301
    [Abstract] [Full Text] [Related]

  • 13. c-Myc overexpression sensitizes Bim-mediated Bax activation for apoptosis induced by histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) through regulating Bcl-2/Bcl-xL expression.
    Jiang X, Tsang YH, Yu Q.
    Int J Biochem Cell Biol; 2007 Dec 20; 39(5):1016-25. PubMed ID: 17331788
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  • 15. BP1 transcriptionally activates bcl-2 and inhibits TNFalpha-induced cell death in MCF7 breast cancer cells.
    Stevenson HS, Fu SW, Pinzone JJ, Rheey J, Simmens SJ, Berg PE.
    Breast Cancer Res; 2007 Dec 20; 9(5):R60. PubMed ID: 17854498
    [Abstract] [Full Text] [Related]

  • 16. Ectopic expression of Bcl-2 and Bcl-xL inhibits apoptosis induced by TNF-related apoptosis-inducing ligand (TRAIL) through suppression of caspases-8, 7, and 3 and BID cleavage in human acute myelogenous leukemia cell line HL-60.
    Lamothe B, Aggarwal BB.
    J Interferon Cytokine Res; 2002 Feb 20; 22(2):269-79. PubMed ID: 11911810
    [Abstract] [Full Text] [Related]

  • 17. Differences in the mechanisms of proapoptotic BH3 proteins binding to Bcl-XL and Bcl-2 quantified in live MCF-7 cells.
    Aranovich A, Liu Q, Collins T, Geng F, Dixit S, Leber B, Andrews DW.
    Mol Cell; 2012 Mar 30; 45(6):754-63. PubMed ID: 22464442
    [Abstract] [Full Text] [Related]

  • 18. Bcl-xS and Bax induce different apoptotic pathways in PC12 cells.
    Lindenboim L, Yuan J, Stein R.
    Oncogene; 2000 Mar 30; 19(14):1783-93. PubMed ID: 10777212
    [Abstract] [Full Text] [Related]

  • 19. Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis.
    Zhou F, Yang Y, Xing D.
    FEBS J; 2011 Feb 30; 278(3):403-13. PubMed ID: 21182587
    [Abstract] [Full Text] [Related]

  • 20. Apoptin-induced cell death is modulated by Bcl-2 family members and is Apaf-1 dependent.
    Burek M, Maddika S, Burek CJ, Daniel PT, Schulze-Osthoff K, Los M.
    Oncogene; 2006 Apr 06; 25(15):2213-22. PubMed ID: 16288204
    [Abstract] [Full Text] [Related]


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