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Journal Abstract Search

95 related items for PubMed ID: 26728879

  • 1. Preclinical toxicity evaluation of a novel immunotoxin, D2C7-(scdsFv)-PE38KDEL, administered via intracerebral convection-enhanced delivery in rats.
    Bao X, Chandramohan V, Reynolds RP, Norton JN, Wetsel WC, Rodriguiz RM, Aryal DK, McLendon RE, Levin ED, Petry NA, Zalutsky MR, Burnett BK, Kuan CT, Pastan IH, Bigner DD.
    Invest New Drugs; 2016 Apr; 34(2):149-58. PubMed ID: 26728879
    [Abstract] [Full Text] [Related]

  • 2. Construction of an immunotoxin, D2C7-(scdsFv)-PE38KDEL, targeting EGFRwt and EGFRvIII for brain tumor therapy.
    Chandramohan V, Bao X, Keir ST, Pegram CN, Szafranski SE, Piao H, Wikstrand CJ, McLendon RE, Kuan CT, Pastan IH, Bigner DD.
    Clin Cancer Res; 2013 Sep 01; 19(17):4717-27. PubMed ID: 23857604
    [Abstract] [Full Text] [Related]

  • 3. EGFR/EGFRvIII-targeted immunotoxin therapy for the treatment of glioblastomas via convection-enhanced delivery.
    Bao X, Pastan I, Bigner DD, Chandramohan V.
    Receptors Clin Investig; 2016 Sep 01; 3(4):. PubMed ID: 28286803
    [Abstract] [Full Text] [Related]

  • 4. Production and quality control assessment of a GLP-grade immunotoxin, D2C7-(scdsFv)-PE38KDEL, for a phase I/II clinical trial.
    Chandramohan V, Pegram CN, Piao H, Szafranski SE, Kuan CT, Pastan IH, Bigner DD.
    Appl Microbiol Biotechnol; 2017 Apr 01; 101(7):2747-2766. PubMed ID: 28013405
    [Abstract] [Full Text] [Related]

  • 5. Improved efficacy against malignant brain tumors with EGFRwt/EGFRvIII targeting immunotoxin and checkpoint inhibitor combinations.
    Chandramohan V, Bao X, Yu X, Parker S, McDowall C, Yu YR, Healy P, Desjardins A, Gunn MD, Gromeier M, Nair SK, Pastan IH, Bigner DD.
    J Immunother Cancer; 2019 May 29; 7(1):142. PubMed ID: 31142380
    [Abstract] [Full Text] [Related]

  • 6. Convection-enhanced delivery of free gadolinium with the recombinant immunotoxin MR1-1.
    Ding D, Kanaly CW, Bigner DD, Cummings TJ, Herndon JE, Pastan I, Raghavan R, Sampson JH.
    J Neurooncol; 2010 May 29; 98(1):1-7. PubMed ID: 19898744
    [Abstract] [Full Text] [Related]

  • 7. A novel recombinant immunotoxin-based therapy targeting wild-type and mutant EGFR improves survival in murine models of glioblastoma.
    Chandramohan V, Bigner DD.
    Oncoimmunology; 2013 Dec 01; 2(12):e26852. PubMed ID: 24498557
    [Abstract] [Full Text] [Related]

  • 8. NTP Toxicology and Carcinogenesis Studies of Coumarin (CAS No. 91-64-5) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
    National Toxicology Program .
    Natl Toxicol Program Tech Rep Ser; 1993 Sep 01; 422():1-340. PubMed ID: 12616289
    [Abstract] [Full Text] [Related]

  • 9. NTP technical report on the toxicity studies of Dibutyl Phthalate (CAS No. 84-74-2) Administered in Feed to F344/N Rats and B6C3F1 Mice.
    Marsman D.
    Toxic Rep Ser; 1995 Apr 01; 30():1-G5. PubMed ID: 12209194
    [Abstract] [Full Text] [Related]

  • 10. NTP Toxicology and Carcinogenesis Studies of o-Benzyl-p-Chlorophenol (CAS No. 120-32-1) in F344/N Rats and B6C3F1 Mice (Gavage Studies).
    National Toxicology Program .
    Natl Toxicol Program Tech Rep Ser; 1994 Jan 01; 424():1-304. PubMed ID: 12616287
    [Abstract] [Full Text] [Related]

  • 11. Evaluation of safety of iridoids rich fraction from Valeriana jatamansi Jones: Acute and sub-chronic toxicity study in mice and rats.
    Xu K, Lin Y, Zhang R, Lan M, Chen C, Li S, Zuo C, Chen C, Zhang T, Yan Z.
    J Ethnopharmacol; 2015 Aug 22; 172():386-94. PubMed ID: 26164073
    [Abstract] [Full Text] [Related]

  • 12. Pharmacokinetics and toxicology of immunotoxins administered into the subarachnoid space in nonhuman primates and rodents.
    Muraszko K, Sung C, Walbridge S, Greenfield L, Dedrick RL, Oldfield EH, Youle RJ.
    Cancer Res; 1993 Aug 15; 53(16):3752-7. PubMed ID: 8339287
    [Abstract] [Full Text] [Related]

  • 13. Concentration rather than dose defines the local brain toxicity of agents that are effectively distributed by convection-enhanced delivery.
    Zhang R, Saito R, Mano Y, Kanamori M, Sonoda Y, Kumabe T, Tominaga T.
    J Neurosci Methods; 2014 Jan 30; 222():131-7. PubMed ID: 24269253
    [Abstract] [Full Text] [Related]

  • 14. Immunotoxin-αCD40 therapy activates innate and adaptive immunity and generates a durable antitumor response in glioblastoma models.
    Parker S, McDowall C, Sanchez-Perez L, Osorio C, Duncker PC, Briley A, Swartz AM, Herndon JE, Yu YA, McLendon RE, Tedder TF, Desjardins A, Ashley DM, Gunn MD, Enterline DS, Knorr DA, Pastan IH, Nair SK, Bigner DD, Chandramohan V.
    Sci Transl Med; 2023 Feb 08; 15(682):eabn5649. PubMed ID: 36753564
    [Abstract] [Full Text] [Related]

  • 15. Ultrasound-assisted convection-enhanced delivery to the brain in vivo with a novel transducer cannula assembly: laboratory investigation.
    Lewis GK, Schulz ZR, Pannullo SC, Southard TL, Olbricht WL.
    J Neurosurg; 2012 Dec 08; 117(6):1128-40. PubMed ID: 22998056
    [Abstract] [Full Text] [Related]

  • 16. Toxicologic evaluations of an immunotoxin, H65-RTA.
    Kung AH, Cavagnaro JA, Makin A, White MA, Kong KN.
    Fundam Appl Toxicol; 1995 Jun 08; 26(1):75-84. PubMed ID: 7657064
    [Abstract] [Full Text] [Related]

  • 17. NTP Toxicology and Carcinogenesis Studies of Pentachloroanisole (CAS No. 1825-21-4) in F344 Rats and B6C3F1 Mice (Feed Studies).
    National Toxicology Program .
    Natl Toxicol Program Tech Rep Ser; 1993 Apr 08; 414():1-284. PubMed ID: 12616284
    [Abstract] [Full Text] [Related]

  • 18. The effects of cyclophosphamide on the toxicity and immunogenicity of ricin A chain immunotoxin in rats.
    Stoudemire JB, Mischak R, Foxall C, Harkonen WS, Del Rio M, Spitler LE.
    Mol Biother; 1990 Sep 08; 2(3):179-84. PubMed ID: 2222902
    [Abstract] [Full Text] [Related]

  • 19. Radiotoxicity of h-R3 monoclonal antibody labeled with 188Re administered intracerebrally in rats.
    Gonzalez B, Casaco A, Alvarez P, Leon M, Arteaga M, Leon A, Santana E, Bada A, Figueredo R, Hernández R, Iznaga-Escobar N, González F, Perez R.
    Hum Exp Toxicol; 2000 Dec 08; 19(12):684-92. PubMed ID: 11291740
    [Abstract] [Full Text] [Related]

  • 20. Multigenerational reproductive study of genistein (Cas No. 446-72-0) in Sprague-Dawley rats (feed study).
    National Toxicology Program.
    Natl Toxicol Program Tech Rep Ser; 2008 Mar 08; (539):1-266. PubMed ID: 18685713
    [Abstract] [Full Text] [Related]

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